Guy's and St Thomas' NHS Foundation Trust

About: Guy's and St Thomas' NHS Foundation Trust is a healthcare organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Randomized controlled trial. The organization has 7686 authors who have published 9631 publications receiving 399353 citations. The organization is also known as: Guy's and St Thomas' National Health Service Foundation Trust & Guy's and St Thomas' National Health Service Trust.

Management of cutaneous squamous cell carcinoma in patients with epidermolysis bullosa: best clinical practice guidelines.

Abstract: This article summarizes recommendations reached following a systematic literature review and expert consensus on the diagnosis and management of cutaneous squamous cell carcinomas in people with epidermolysis bullosa. The guidelines are intended to help inform decision making by clinicians dealing with this complex complication of a devastating disease.

Feasibility, acceptability and potential effectiveness of Dignity Therapy for older people in care homes: a phase II randomized controlled trial of a brief palliative care psychotherapy.

Abstract: Background:A pilot study of Dignity Therapy conducted with hospice patients reported high levels of self-reported benefits of the psychotherapy.Aim:To assess the feasibility, acceptability and potential effectiveness of Dignity Therapy to reduce distress in older people in care homes.Design:A randomized controlled open-label trial (ISRCTN37589515). Setting and participants: 60 residents aged 65+ with no major cognitive impairment living in care homes in London, UK.Intervention:Dignity Therapy, a brief palliative care psychotherapy.Outcomes:Potential effectiveness (dignity-related distress, depression, hopefulness, quality of life at baseline and 1 and 8-week follow-up); acceptability (residents’ views on self-reported benefits of Dignity Therapy/the Dignity Therapy study); and feasibility (time taken to deliver the intervention).Results:We randomized 60/755 (8%) residents: 29 – control, 31 – intervention. We found no significant differences between groups on measures of potential effectiveness at any time...

Social (pragmatic) communication disorder: a research review of this new DSM-5 diagnostic category

Abstract: Social (pragmatic) communication disorder (SCD) is a new diagnostic category in the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5). The purpose of this review is to describe and synthesize the relevant literature from language and autism spectrum disorder (ASD) research relating to pragmatic language impairment and other previously used terms that relate to SCD. The long-standing debate regarding how social communication/pragmatic impairments overlap and/or differ from language impairments, ASD, and other neurodevelopmental disorders is examined. The possible impact of the addition of SCD diagnostic category and directions for future research are also discussed.

Guidelines on the management of AL amyloidosis.

Abstract: National Amyloidosis Centre, Division of Medicine, UCL, London Department of Haematology, Bristol Haematology and Oncology Centre, Bristol Department of Haematology, St Bartholomew's Hospital, London Department of Haematology, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool Departments of Oncology and Haematology, Guy's & St Thomas' NHS Foundation Trust, London Department of Haematology, Birmingham Heartlands Hospital and School of Cancer Sciences, University of Birmingham, Birmingham