Institution
Hannam University
Education•Daejeon, South Korea•
About: Hannam University is a education organization based out in Daejeon, South Korea. It is known for research contribution in the topics: The Internet & Membrane. The organization has 1667 authors who have published 3149 publications receiving 52184 citations.
Papers published on a yearly basis
Papers
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Daniel J. Klionsky1, Amal Kamal Abdel-Aziz2, Sara Abdelfatah3, Mahmoud Abdellatif4 +2980 more•Institutions (777)
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Abstract: In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
1,129 citations
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TL;DR: PCL cylindrical scaffolds fabricated by the centrifugation method can be a good tool for the systematic studies of the interactions between cells or tissues and scaffolds with different pore size.
618 citations
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TL;DR: The studies illustrated the potential use of SMEDDS for the delivery of hydrophobic compounds, such as simvastatin by the oral route, and its potential use for in vitro dissolution and bioavailability assessment.
518 citations
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TL;DR: Specific medicinal plants, herbs and spices from Latin America have potential for hyperglycemia and hypertension prevention associated with Type 2 diabetes.
498 citations
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TL;DR: Ordered uniform porous carbon frameworks showing interesting morphology variations were synthesized against removable colloidal silica crystalline templates through simply altering acid catalyst sites for acid-catalyzed polymerization.
Abstract: Ordered uniform porous carbon frameworks showing interesting morphology variations were synthesized against removable colloidal silica crystalline templates through simply altering acid catalyst sites for acid-catalyzed polymerization. These highly ordered uniform porous carbons as a catalyst supporter resulted in much improved catalytic activity for methanol oxidation in a fuel cell.
488 citations
Authors
Showing all 1673 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jong-Sung Yu | 124 | 1051 | 72637 |
Baizeng Fang | 53 | 133 | 8265 |
Seong-Ho Choi | 52 | 659 | 11577 |
Anantha Iyengar Gopalan | 50 | 288 | 8570 |
Han Young Woo | 49 | 348 | 10380 |
Kwang-Pill Lee | 49 | 233 | 7623 |
Jin Ho Lee | 48 | 166 | 9592 |
Sang Jin Lee | 48 | 195 | 10282 |
Dong-Yol Yang | 42 | 348 | 6808 |
Sung-Ho Jin | 42 | 460 | 8261 |
Chulhee Kim | 42 | 129 | 6106 |
Debnath Bhattacharyya | 39 | 578 | 6867 |
Jong K. Keum | 39 | 131 | 4893 |
Sung Joo Hwang | 37 | 192 | 5413 |
Soon Hong Yuk | 37 | 109 | 4438 |