Harbin Engineering University

About: Harbin Engineering University is a education organization based out in Harbin, Heilongjiang, China. It is known for research contribution in the topics: Control theory & Computer science. The organization has 31149 authors who have published 27940 publications receiving 276787 citations. The organization is also known as: HEU.

Robust NSV Fault-Tolerant Control System Design Against Actuator Faults and Control Surface Damage Under Actuator Dynamics

Abstract: In this paper, a decentralized fault-tolerant control (FTC) system is proposed for near-space vehicle (NSV) attitude dynamics. First, NSV reentry attitude dyna mic models with an uncertainty, actuator failure models, and a control surface damage model are described. Next, a new local fault identification algorithm is proposed to iden tify different types of actuator faults, which is based on multiobserver techniques. The local fault identification is constituted by a fault detection observer, fault parameter identification observers, and a decision-making mechanism. Then, a global adaptive sliding-mode observer is used to design the command filter backstepping fault- tolerant controller. Our focus is on the accommodation for actuator faults, control surface damage, uncertainties, and the resulting disturbances of the NSV. Finally, simulation results are given to demonstrate the effectiveness and poten tial of the proposed FTC scheme.

Hollow Structured Y2O3:Yb/Er–CuxS Nanospheres with Controllable Size for Simultaneous Chemo/Photothermal Therapy and Bioimaging

Abstract: To integrate photothermal therapy (PTT) with chemotherapy for improved antitumor efficiency, we designed a novel multifunctional composite by attaching CuxS nanoparticles onto the surface of Y2O3:Yb/Er hollow spheres through a combined coprecipitation and subsequent hydrothermal route. By altering the initial pH values for the synthesis of precursors, the size and structure properties of the final composites can controllably be tuned. The conjugated folic acid (FA) makes the composite recognize the targeted cancer cells and the attached CuxS nanoparticles endow the composite with photothermal function. It is found that the release of doxorubicin (DOX) from the functional carrier could be triggered by both pH value and near-infrared (NIR) radiation. In particular, both PTT and chemotherapy can be simultaneously driven by 980 nm laser irradiation. The synergistic therapeutic effect based on PTT and chemotherapy can lead to low in vitro viability of 12.9% and highly strong inhibition of animal H22 tumor in v...