Harbin Engineering University

About: Harbin Engineering University is a education organization based out in Harbin, Heilongjiang, China. It is known for research contribution in the topics: Control theory & Microstructure. The organization has 31149 authors who have published 27940 publications receiving 276787 citations. The organization is also known as: HEU.

Intelligent Fe-Mn Layered Double Hydroxides Nanosheets Anchored with Upconversion Nanoparticles for Oxygen-Elevated Synergetic Therapy and Bioimaging.

Abstract: Multimodal synergistic therapy based on photodynamic therapy (PDT), photothermal therapy (PTT), and chemodynamic therapy (CDT) has attracted increasing attention in cancer therapy. However, the scant therapeutic efficiency is always a barrier for further application. Herein, a smart tumor microenvironment (TME) responsive nanocatalysts are developed by adopting Fe-Mn layered double hydroxides (FeMn-LDH) as an effective photothermal nanocarrier to load mesoporous silica and chlorin e6 (Ce6)-covalently coated upconversion nanoparticles (UCSP) for multimodal imaging for directed therapy. Under acidic TME, FeMn-LDH degrades into Fe3+ and Mn2+ ions to initiate a Fenton-like reaction inducing CDT and enhancing magnetic resonance imaging. Additionally, Fe3+ can decompose H2 O2 to oxygen (O2 ), enhancing PDT guided by UCSP. As a representative noninvasive imaging probe, the upconversion luminescence will recover after decomposition of FeMn-LDH, and provide high-resolution upconversion luminescent imaging guidance for pinpointed PDT. Moreover, the photothermal properties of FeMn-LDH can further enhance CDT effects. The synergistic therapy and multifunctional imaging can realize the integration of diagnosis and treatment.

Fog-Computing-Enabled Cognitive Network Function Virtualization for an Information-Centric Future Internet

Abstract: Information-centric networking (ICN) is an important trend that will impact the future of the Internet. ICN caters to large content consumption patterns while achieving high performance. New features in the information-centric future Internet, such as caching, name-based routing, and content-based security, bring novel challenges to a decentralized environment. On one hand, the processing capabilities on the edge in an information-centric future Internet need to implement smart analysis for large quantities of content. On the other hand, the computational and storage resources need to be configured and controlled on demand and based on cognition of the content from users. To address these challenges, this article proposes a fog-computing- enabled cognitive network functions virtualization approach for an information-centric future Internet. We first propose an on-demand caching function virtualization scheme and design a communication scheme between the fog nodes and the future Internet nodes for the forwarding process. Then, to attain smart control for related operations (i.e., routing, cache policy, and security), we propose a control function virtualization approach. Finally, a cognitive resource configuration mechanism is proposed. The simulation results show the advantages and efficiency of the proposed approach.