Harbin Engineering University

About: Harbin Engineering University is a education organization based out in Harbin, Heilongjiang, China. It is known for research contribution in the topics: Control theory & Microstructure. The organization has 31149 authors who have published 27940 publications receiving 276787 citations. The organization is also known as: HEU.

Enhanced Antitumor Efficacy by 808 nm Laser‐Induced Synergistic Photothermal and Photodynamic Therapy Based on a Indocyanine‐Green‐Attached W18O49 Nanostructure

Abstract: A novel nanoplatform based on tungsten oxide (W18O49, WO) and indocyanine green (ICG) for dual-modal photothermal therapy (PTT) and photodynamic therapy (PDT) has been successfully constructed. In this design, the hierarchical unique nanorod-bundled W18O49 nanostructures play roles in being not only as an efficient photothermal agent for PTT but also as a potential nanovehicle for ICG molecules via electrostatic adsorption after modified with trimethylammonium groups on their surface. It is found that the ability of ICG to produce cytotoxic reactive oxygen species for PDT is well maintained after being attached on the WO, thus the as-obtained WO@ICG can achieve a synergistic effect of combined PTT and PDT under single 808 nm near-infrared (NIR) laser excitation. Notably, compared with PTT or PDT alone, the enhanced HeLa cells lethality of the 808 nm laser triggered dual-modal therapy is observed. The in vivo animal experiments have shown that WO@ICG has effective solid tumor ablation effect with 808 nm NIR light irradiation, revealing the potential of these nanocomposites as a NIR-mediated dual-modal therapeutic platform for cancer treatment.

Tunable multicolor and bright white emission of one-dimensional NaLuF4:Yb3+,Ln3+ (Ln = Er, Tm, Ho, Er/Tm, Tm/Ho) microstructures

Abstract: Well-defined one-dimensional NaLuF4:Yb3+,Er3+/Tm3+/Ho3+ microtubes and microrods were successfully prepared by a surfactant-free molten salt method for the first time. It is found that with the prolonged time, the phase of NaLuF4 transforms from cubic to hexagonal, while the morphology changes from nanoparticles to microtubes then to microrods. Moreover, upon 980 nm laser diode (LD) excitation, white up-conversion (UC) light was successfully achieved by properly tuning the sensitizer (Yb3+) concentration in the host matrix. The relative emission intensities of different emission colors in Yb3+/Er3+, Yb3+/Tm3+, and Yb3+/Ho3+ doped β-NaLuF4 can be precisely adjusted in a broad range by tuning the Yb3+ doping concentration. Consequently, effective UC emissions with multicolors and a strong white light can be realized in β-NaLuF4:Yb3+/Er3+/Tm3+, and β-NaLuF4:Yb3+/Tm3+/Ho3+ structures by the appropriate control of the emission intensity balance for the three blue, green, and red basic colors. UC mechanisms in the co-doping and tri-doping β-NaLuF4 samples were analyzed in detail based on the emission spectra and the plot of luminescence intensity to pump power. The as-obtained abundant luminescence colors in a much wide region contribute themselves great potential applications in various fields. Furthermore, the paper also provides an effective and facile approach to gain a desired color by manipulating the sensitizer concentration.

On potential wells and applications to semilinear hyperbolic equations and parabolic equations

Abstract: In this paper we generalize the family of potential wells to the initial boundary value problem of semilinear hyperbolic equations and parabolic equations u tt - Δ u = f ( u ) , x ∈ Ω , t > 0 , u ( x , 0 ) = u 0 ( x ) , u t ( x , 0 ) = u 1 ( x ) , x ∈ Ω , u ( x , t ) = 0 , x ∈ ∂ Ω , t ⩾ 0 and u t - Δ u = f ( u ) , x ∈ Ω , t > 0 , u ( x , 0 ) = u 0 ( x ) , x ∈ Ω , u ( x , t ) = 0 , x ∈ ∂ Ω , t ⩾ 0 , not only give a threshold result of global existence and nonexistence of solutions, but also obtain the vacuum isolating of solutions Finally we prove the global existence of solutions for above problem with critical initial conditions I ( u 0 ) ⩾ 0 , E ( 0 ) = d or I ( u 0 ) ⩾ 0 , J ( u 0 ) = d So Payne and Sattinger's results are generalized and improved in essential