Helsinki Institute for Information Technology

About: Helsinki Institute for Information Technology is a facility organization based out in Espoo, Finland. It is known for research contribution in the topics: Population & Bayesian network. The organization has 630 authors who have published 1962 publications receiving 63426 citations.

Bayesian meta-analysis across genome-wide association studies of diverse phenotypes.

Abstract: Genome-wide association studies (GWAS) are a powerful tool for understanding the genetic basis of diseases and traits, but most studies have been conducted in isolation, with a focus on either a single or a set of closely related phenotypes. We describe MetABF, a simple Bayesian framework for performing integrative meta-analysis across multiple GWAS using summary statistics. The approach is applicable across a wide range of study designs and can increase the power by 50% compared with standard frequentist tests when only a subset of studies have a true effect. We demonstrate its utility in a meta-analysis of 20 diverse GWAS which were part of the Wellcome Trust Case Control Consortium 2. The novelty of the approach is its ability to explore, and assess the evidence for a range of possible true patterns of association across studies in a computationally efficient framework.

A simple approach for finding the globally optimal Bayesian network structure

Abstract: We study the problem of learning the best Bayesian network structure with respect to a decomposable score such as BDe, BIC or AIC. This problem is known to be NP-hard, which means that solving it becomes quickly infeasible as the number of variables increases. Nevertheless, in this paper we show that it is possible to learn the best Bayesian network structure with over 30 variables, which covers many practically interesting cases. Our algorithm is less complicated and more efficient than the techniques presented earlier. It can be easily parallelized, and offers a possibility for efficient exploration of the best networks consistent with different variable orderings. In the experimental part of the paper we compare the performance of the algorithm to the previous state-of-the-art algorithm. Free source-code and an online-demo can be found at this http URL.

Design ideas for everyday mobile and ubiquitous computing based on qualitative user data

Abstract: Academic research in mobile and ubiquitous computing has been mainly technology-driven There is not enough understanding on what everyday needs are related to future mobile and ubiqitous computing In this paper we will demonstrate that qualitative user data can be successfully utilized in designing for everyday activities of largely neglected user groups like the elderly We will show how ethnographically based research can benefit the innovation of product concepts

Using viewing statistics to control energy and traffic overhead in mobile video streaming

Abstract: Video streaming can drain a smartphone battery quickly. A large part of the energy consumed goes to wireless communication. In this article, we first study the energy efficiency of different video content delivery strategies used by service providers and identify a number of sources of energy inefficiency. Specifically, we find a fundamental tradeoff in energy waste between prefetching small and large chunks of video content: small chunks are bad because each download causes a fixed tail energy to be spent regardless of the amount of content downloaded, whereas large chunks increase the risk of downloading data that user will never view because of abandoning the video. Hence, the key to optimal strategy lies in the ability to predict when the user might abandon viewing prematurely. We then propose an algorithm called eSchedule that uses viewing statistics to predict viewer behavior and computes an energy optimal download strategy for a given mobile client. The algorithm also includes a mechanism for explicit control of traffic overhead, i.e., unnecessary download of content that the user will never watch. Our evaluation results suggest that the algorithm can cut the energy waste down to less than half compared to other strategies. We also present and experiment with an Android prototype that integrates eSchedule into a YouTube downloader.