Helsinki Institute for Information Technology

About: Helsinki Institute for Information Technology is a facility organization based out in Espoo, Finland. It is known for research contribution in the topics: Population & Bayesian network. The organization has 630 authors who have published 1962 publications receiving 63426 citations.

"Let Everything Turn Well in Your Wife": Generation of Adult Humor Using Lexical Constraints

Abstract: We propose a method for automated generation of adult humor by lexical replacement and present empirical evaluation results of the obtained humor. We propose three types of lexical constraints as building blocks of humorous word substitution: constraints concerning the similarity of sounds or spellings of the original word and the substitute, a constraint requiring the substitute to be a taboo word, and constraints concerning the position and context of the replacement. Empirical evidence from extensive user studies indicates that these constraints can increase the effectiveness of humor generation significantly.

Identification of drug candidates and repurposing opportunities through compound-target interaction networks.

Abstract: Introduction: System-wide identification of both on- and off-targets of chemical probes provides improved understanding of their therapeutic potential and possible adverse effects, thereby accelerating and de-risking drug discovery process. Given the high costs of experimental profiling of the complete target space of drug-like compounds, computational models offer systematic means for guiding these mapping efforts. These models suggest the most potent interactions for further experimental or pre-clinical evaluation both in cell line models and in patient-derived material.Areas covered: The authors focus here on network-based machine learning models and their use in the prediction of novel compound–target interactions both in target-based and phenotype-based drug discovery applications. While currently being used mainly in complementing the experimentally mapped compound–target networks for drug repurposing applications, such as extending the target space of already approved drugs, these network pharmacol...

Appropriation of a MMS-based comic creator: from system functionalities to resources for action

Abstract: Technologies can be used - or appropriated - in different ways by different users, but how do the use patterns evolve, and how can design facilitate such evolution? This paper approaches these questions in light of a case study in which a group of 8 high school students used Comeks, a mobile comic strip creator that enables users to exchange rich, expressive multimedia messages. A qualitative analysis of the use processes shows how users turned the functionalities embodied in Comeks into particular resources for communication during the 9-week trial period. The paper discusses the relationship of functionalities of the artifact and the development of resources by presenting how functionalities can be designed to support three ways to appropriate communication technologies: increasing technical mastery, re-channeling existing communication into the new medium and inventing new communicative acts between users.

Building social discourse around mobile photos: a systemic perspective

Abstract: Camera phones have been viewed simplistically as digital cameras with poor picture quality while neglecting the utility of the two key functionalities of mobile phones: network connection and access to personal information. This is the first HCI paper to examine mobile photos from a systemic perspective: how assignment of phases of mobile photo lifecycle to different platforms affects social discourse around shared photos. We conducted a 6-week user trial of MobShare, a tripartite system with dedicated functions and task couplings for a mobile phone, a server, and a PC browser. We analyze how MobShare's couplings and distribution of functionalities affected the observed types of social discourse that formed around mobile photos: in-group post-event discourse, self-documents and reports, greetings and thanks. Several central design issues arising from the systemic view are discussed: heterogeneity of environments, integration and distribution of functionalities, couplings and decouplings of interaction tasks, notification mechanisms, and provision of necessary UI resources for different tasks.