Henan University of Technology

About: Henan University of Technology is a education organization based out in Zhengzhou, China. It is known for research contribution in the topics: Catalysis & Chemistry. The organization has 7648 authors who have published 6503 publications receiving 73067 citations. The organization is also known as: Hénán Gōngyè Dàxué.

Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer.

Abstract: Currently, particular focus is placed on the implication of autophagy in a variety of human diseases, including cancer. Discovery of small-molecule modulators of autophagy as well as their ...

Application of Deep Eutectic Solvents in Food Analysis: A Review

Abstract: Deep eutectic solvents (DESs) have emerged recently as new and green solvents. DESs can be used for extraction and separation of both inorganic metallic components and organic compounds such as phenolic compounds, flavonoids, sugars, and aromatic amines from food samples. DESs possess a tunable property simply by adjusting the ratio of hydrogen bond acceptors to the hydrogen bond donors. As a green extraction medium, DESs have various applications in the pretreatment process and improve the efficiency of different food analyses. This review summarizes the findings of recent studies on the development, production, application, and efficacy of DESs in the pretreatment process of various food analyses.

Boundary integral based graded element for elastic analysis of 2D functionally graded plates

Abstract: A two-dimensional (2D) elastic analysis of functionally graded materials (FGMs) is conducted using the proposed boundary integral based graded element formulation. The graded element model is based on independent internal and frame field approximations. The elemental stiffness contains element boundary integrals only and is calculated using the exact expression of the graded material property. In the construction of the element model, the fundamental solutions of functionally graded plate with quadratic variation of elastic properties are employed to construct the internal approximation and then the graded element is constructed, in which the material definition entails naturally graded variation. Three numerical examples are considered: verification of fundamental solutions, a functionally graded cantilever beam, and a functionally graded link bar, to assess the performance of the hybrid graded model and to show the advantages of FGMs over homogeneous materials.

Genome comparison of two Magnaporthe oryzae field isolates reveals genome variations and potential virulence effectors

Abstract: Rice blast caused by the fungus Magnaporthe oryzae is an important disease in virtually every rice growing region of the world, which leads to significant annual decreases of grain quality and yield. To prevent disease, resistance genes in rice have been cloned and introduced into susceptible cultivars. However, introduced resistance can often be broken within few years of release, often due to mutation of cognate avirulence genes in fungal field populations. To better understand the pattern of mutation of M. oryzae field isolates under natural selection forces, we used a next generation sequencing approach to analyze the genomes of two field isolates FJ81278 and HN19311, as well as the transcriptome of FJ81278. By comparing the de novo genome assemblies of the two isolates against the finished reference strain 70–15, we identified extensive polymorphisms including unique genes, SNPs (single nucleotide polymorphism) and indels, structural variations, copy number variations, and loci under strong positive selection. The 1.75 MB of isolate-specific genome content carrying 118 novel genes from FJ81278, and 0.83 MB from HN19311 were also identified. By analyzing secreted proteins carrying polymorphisms, in total 256 candidate virulence effectors were found and 6 were chosen for functional characterization. We provide results from genome comparison analysis showing extensive genome variation, and generated a list of M. oryzae candidate virulence effectors for functional characterization.