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TL;DR: In this article, a micro-capacitive sensor-based bio-impedance classification system for identification of malignant cells in a known volume (400 $\mu \text{L}$ ) of biological tissue sample is presented.
Abstract: This article presents development of a microcapacitive sensor-based bio-impedance classification system for identification of malignant cells in a known volume (400 $\mu \text{L}$ ) of biological tissue sample Malignancy induces various physical changes in an affected cell, among which increased intracellular water and sodium ion content are a couple of prominent ones In this work, the change in electrical properties of a cell [here white blood cell (WBC)] that is membrane and cytoplasm permittivity due to afore-mentioned reasons is used for distinguishing malignant from normal cells based on their deviation in bio-impedance signature This change in bio-impedance signature of the WBC is measured by exciting the mentioned microcapacitive sensor by a 2 V p-p signal The developed system consists of an on-board impedance analyzer to carry out bio-impedance spectroscopy over a frequency range of 1–100 kHz The bio-impedance data are then obtained from the sensor for different concentrations of cultured human malignant and normal white blood cells The difference in impedance values between concentrations is then used as a discerning factor for identification the degree of malignancy, for which an artificial neural network (ANN) is employed A detailed study considering detection efficiency for this ANN revealed classification accuracy up to 950%, upon which this ANN model is transferred to a portable single board computer (SBC) along with other associated circuitry that could carry out the same classification at a nominal power consumption of 51645 mW
15 citations
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TL;DR: In this paper, a sonochemical synthetic approach was used in fabricating PdCo/MnO2 catalyst for the study of ethanol oxidation reaction in alkali medium. But, the performance of Pd61Co39/mnO2 was not evaluated.
Abstract: The present study deals with sonochemical synthetic approach in fabricating PdCo/MnO2 catalyst for the study of ethanol oxidation reaction in alkali medium. SEM and TEM images reveal that MnO2 morphology is changed from nanowire to nanorod during intercalation of Pd, Co NPs in the support materials. Charge transfer across the electrode–electrolyte interface becomes facile due to (2 × 2) pore tunnels of α MnO2. Lowering of Pd loading around 40% in the catalyst matrix by Co not only makes the catalyst cheaper but also enhances the ethanol oxidation current by 66.3% compared to Pd/C. Extensive electrolysis on Pd61Co39/MnO2 over a considerable span of potential is reflected in the voltammetric features, typically demonstrating the synergistic effect of the Pd–Co ad atoms ingrained on α MnO2 structure. Chrono-amperometric analysis for an extended period indicates excellent sustainability of Pd61Co39/MnO2 in the oxidation environment. The yield of oxidation products on Pd61Co39/MnO2, derived from ion chromatogr...
15 citations
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TL;DR: A multi-objective inventory model under both stock-dependent demand rate and holding cost rate with fuzzy random coefficients is investigated to determine optimal order quantity and inventory level such that the total profit and wastage cost are maximized and minimize for the retailer respectively.
Abstract: In this paper, we investigated a multi-objective inventory model under both stock-dependent demand rate and holding cost rate with fuzzy random coefficients. Chance constrained fuzzy random multi-objective model and a traditional solution procedure based on an interactive fuzzy satisfying method are discussed. In addition, the technique of fuzzy random simulation is applied to deal with general fuzzy random objective functions and fuzzy random constraints which are usually difficult to converted into their crisp equivalents. The purposed of this study is to determine optimal order quantity and inventory level such that the total profit and wastage cost are maximized and minimize for the retailer respectively. Finally, illustrate example is given in order to show the application of the proposed model.
15 citations
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TL;DR: The competitive binding study in the presence of ethidium bromide suggests that the complex interacts with calf thymus DNA (CT DNA) through partial intercalation through partialintercalation of the copper complex within DNA.
Abstract: Photoinduced intramolecular electron transfer occurs in the triplet state within the complex [Htyr-Cu-phen](+) (Htyr = l-tyrosinato; phen = 1,10-phenanthroline) from tyrosine to phenanthroline. For this linked donor-acceptor system, a prominent magnetic field effect (MFE) is observed for the triplet-born radicals. The competitive binding study in the presence of ethidium bromide suggests that the complex interacts with calf thymus DNA (CT DNA) through partial intercalation. The photoexcited copper complex can oxidize DNA in a deoxygenated environment. Though the oxidation of tyrosine is thermodynamically more favorable than the oxidation of guanine, the primary electron transfer occurs from the DNA base to the phen ligand. A prominent MFE is observed for this noncovalently bound triplet-born guanine radical and phen radical anion. The process of partial intercalation of the copper complex within DNA is responsible for this rare observation.
15 citations
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TL;DR: It is hypothesized that the Ligand 6 may form a potential drug candidate for RdRpC inhibition in the clinical treatment of ZIKV infection and show a remarkable docking profile against the strictly conserved aspartate residues of the RdRPC active site.
15 citations
Authors
Showing all 581 results
Name | H-index | Papers | Citations |
---|---|---|---|
Debnath Bhattacharyya | 39 | 578 | 6867 |
Samiran Mitra | 38 | 198 | 5108 |
Dipankar Chakravorty | 35 | 369 | 5288 |
S. Saha Ray | 34 | 217 | 3888 |
Tai-hoon Kim | 33 | 526 | 4974 |
Anindya Sen | 29 | 109 | 3472 |
Ujjal Debnath | 29 | 335 | 3828 |
Anirban Mukhopadhyay | 29 | 169 | 3200 |
Avijit Ghosh | 28 | 121 | 2639 |
Mrinal K. Ghosh | 26 | 64 | 2243 |
Biswanath Bhunia | 23 | 75 | 1466 |
Jayati Datta | 23 | 55 | 1520 |
Nabarun Bhattacharyya | 23 | 136 | 1960 |
Pinaki Bhattacharya | 19 | 114 | 1193 |
Dwaipayan Sen | 18 | 71 | 1086 |