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Institution

Hokkaido University

EducationSapporo, Hokkaidô, Japan
About: Hokkaido University is a education organization based out in Sapporo, Hokkaidô, Japan. It is known for research contribution in the topics: Population & Catalysis. The organization has 53925 authors who have published 115403 publications receiving 2651647 citations. The organization is also known as: Hokudai & Hokkaidō daigaku.
Topics: Population, Catalysis, Gene, Transplantation, Virus


Papers
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Journal ArticleDOI
TL;DR: In vitro toxicity of Ag-NPs at noncytotoxic doses in human hepatoma cell line, HepG2, is evaluated and it is concluded that both "nanosized particle of Ag" as well as "ionic Ag+" contribute to the toxic effects of Ag.
Abstract: Although it has been reported that silver nanoparticles (Ag-NPs) have strong acute toxic effects to various cultured cells, the toxic effects at noncytotoxic doses are still unknown. We, therefore, evaluated in vitro toxicity of Ag-NPs at noncytotoxic doses in human hepatoma cell line, HepG2, based on cell viability assay, micronucleus test, and DNA microarray analysis. We also used polystyrene nanoparticles (PS-NPs) and silver carbonate (Ag2CO3) as test materials to compare the toxic effects with respect to different raw chemical composition and form of silver. The cell viability assay demonstrated that Ag-NPs accelerated cell proliferation at low doses ( 1.0 mg/L) and induced abnormal cellular morphology, displaying cellular shrinkage and acquisition of an irregular shape. In addit...

624 citations

Journal ArticleDOI
TL;DR: The apparent decrease in prevalence of H. pylori accompanying the Westernization of Japan may eventually be accompanied by a reduction in the frequency of atrophic gastritis, the precursor lesion of the epidemic form of gastric carcinoma, and ultimately result in a decrease in the incidence of gastRIC carcinoma in Japan.

622 citations

Journal ArticleDOI
TL;DR: In this article, a comprehensive review on membrane cleaning in MBRs is presented, and the existing challenges and future research efforts are discussed in order to ensure the development of membrane cleaning toward a more effective and sustainable way in MBR.

621 citations

Journal ArticleDOI
TL;DR: In this paper, the authors discuss the interpretation of what we know and what we do not know in a scientific sense, in alphabetical order from activity, band structure, and crystallinity to X-ray photoelectron spectroscopy.
Abstract: Topics, in alphabetical order from “Activity”, “Band structure” and “Crystallinity” to “X-ray photoelectron spectroscopy”, “Yield” and “Z-scheme photocatalysis”, related to photocatalysis and photoelectrochemical reaction are discussed with interpretation of what we know and what we do not know in a scientific sense.

620 citations

Journal ArticleDOI
TL;DR: Double‐network (DN) hydrogels with high mechanical strength have been synthesized using the natural polymers bacterial cellulose and gelatin, and an enhancement in the mechanical strength was also observed for the combination of BC with polysaccharides, such as sodium alginate, gellan gum, and ι‐carrageenan.
Abstract: Double-network (DN) hydrogels with high mechanical strength have been synthesized using the natural polymers bacterial cellulose (BC) and gelatin. As-prepared BC contains 90 % water that can easily be squeezed out, with no more recovery in its swelling property. Gelatin gel is brittle and is easily broken into fragments under a modest compression. In contrast, the fracture strength and elastic modulus of a BC–gelatin DN gel under compressive stress are on the order of megapascals, which are several orders of magnitude higher than those of gelatin gel, and almost equivalent to those of articular cartilage. A similar enhancement in the mechanical strength was also observed for the combination of BC with polysaccharides, such as sodium alginate, gellan gum, and ι-carrageenan.

619 citations


Authors

Showing all 54156 results

NameH-indexPapersCitations
Shizuo Akira2611308320561
Yi Cui2201015199725
John F. Hartwig14571466472
Yoshihiro Kawaoka13988375087
David Y. Graham138104780886
Takashi Kadowaki13787389729
Kazunari Domen13090877964
Susumu Kitagawa12580969594
Toshikazu Nakamura12173251374
Toshio Hirano12040155721
Li-Jun Wan11363952128
Wenbin Lin11347456786
Xiaoming Li113193272445
Jinhua Ye11265849496
Terence Tao11160694316
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023127
2022427
20214,743
20204,805
20194,363
20184,112