Hong Kong Baptist University

About: Hong Kong Baptist University is a education organization based out in Hong Kong, China. It is known for research contribution in the topics: Population & China. The organization has 7811 authors who have published 18919 publications receiving 555274 citations. The organization is also known as: Hong Kong Baptist College & HKBU.

Method of fundamental solutions with regularization techniques for Cauchy problems of elliptic operators

Abstract: In this paper we combine the method of fundamental solutions with various regularization techniques to solve Cauchy problems of elliptic differential operators. The main idea is to approximate the unknown solution by a linear combination of fundamental solutions whose singularities are located outside the solution domain. To solve effectively the discrete ill-posed resultant matrix, we use three regularization strategies under three different choices for the regularization parameter. Several examples on problems with smooth and non-smooth geometries in 2D and 3D spaces using under-, equally, and over-specified Cauchy data on an accessible boundary are given. Numerical results indicate that the generalized cross-validation and L -curve choice rulers for Tikhonov regularization and damped singular value decomposition strategy are most effective when using the same numbers of collocation and source points. It has also been observed that the use of more Cauchy data will greatly improve the accuracy of the approximate solution.

Endocrine disrupting chemicals: Multiple effects on testicular signaling and spermatogenesis.

Abstract: In the past 200 years, an enormous number of synthetic chemicals with diverse structural features have been produced for industrial, medical and domestic purposes These chemicals, originally thought to have little or no biological toxicity, are widely used in our daily lives as well as are commonly present in foods It was not until the first World Wildlife Federation Wingspread Conference held in 1994 were concerns about the endocrine disrupting (ED) effects of these chemicals articulated The potential hazardous effects of endocrine disrupting chemicals (EDCs) on human health and ecological well-being are one of the global concerns that affect the health and propagation of human beings Considerable numbers of studies indicated that endocrine disruption is linked to "the developmental basis of adult disease," highlighting the significant effects of EDC exposure on a developing organism, leading to the propensity of an individual to develop a disease or dysfunction in later life In this review, we intend to provide environmental, epidemiological and experimental data to associate pollutant exposure with reproductive disorders, in particular on the development and function of the male reproductive system Possible effects of pollutant exposure on the processes of embryonic development, like sex determination and masculinization are described In addition, the effects of pollutant exposure on hypothalamus-pituitary-gonadal axis, testicular signaling, steroidogenesis and spermatogenesis are also discussed