Institution
Hong Kong Baptist University
Education•Hong Kong, China•
About: Hong Kong Baptist University is a education organization based out in Hong Kong, China. It is known for research contribution in the topics: Population & China. The organization has 7811 authors who have published 18919 publications receiving 555274 citations. The organization is also known as: Hong Kong Baptist College & HKBU.
Topics: Population, China, Catalysis, Cluster analysis, Organic solar cell
Papers published on a yearly basis
Papers
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TL;DR: Generally, protein classification is a multi‐class classification problem and can be reduced to a set of binary classification problems, where one classifier is designed for each class, but in this case the number of proteins in one class is usually much smaller than that of the proteins outside the class.
Abstract: Generally, protein classification is a multi-class classification problem and can be reduced to a set of binary classification problems, where one classifier is designed for each class. The proteins in one class are seen as positive examples while those outside the class are seen as negative examples. However, the imbalanced problem will arise in this case because the number of proteins in one class is usually much smaller than that of the proteins outside the class. As a result, the imbalanced data cause classifiers to tend to overfit and to perform poorly in particular on the minority class. This article presents a new technique for protein classification with imbalanced data. First, we propose a new algorithm to overcome the imbalanced problem in protein classification with a new sampling technique and a committee of classifiers. Then, classifiers trained in different feature spaces are combined together to further improve the accuracy of protein classification. The numerical experiments on benchmark datasets show promising results, which confirms the effectiveness of the proposed method in terms of accuracy. The Matlab code and supplementary materials are available at http://eserver2.sat.iis.u-tokyo.ac.jp/ approximately xmzhao/proteins.html.
130 citations
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130 citations
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TL;DR: AnnoPred is introduced, a principled framework that leverages diverse types of genomic and epigenomic functional annotations in genetic risk prediction for complex diseases and achieves consistently improved prediction accuracy in both extensive simulations and real data.
Abstract: Genetic risk prediction is an important goal in human genetics research and precision medicine. Accurate prediction models will have great impacts on both disease prevention and early treatment strategies. Despite the identification of thousands of disease-associated genetic variants through genome wide association studies (GWAS), genetic risk prediction accuracy remains moderate for most diseases, which is largely due to the challenges in both identifying all the functionally relevant variants and accurately estimating their effect sizes in the presence of linkage disequilibrium. In this paper, we introduce AnnoPred, a principled framework that leverages diverse types of genomic and epigenomic functional annotations in genetic risk prediction for complex diseases. AnnoPred is trained using GWAS summary statistics in a Bayesian framework in which we explicitly model various functional annotations and allow for linkage disequilibrium estimated from reference genotype data. Compared with state-of-the-art risk prediction methods, AnnoPred achieves consistently improved prediction accuracy in both extensive simulations and real data.
130 citations
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TL;DR: The nutritional value of the fermented soy products gains much attention due to its increased levels compared to the non-fermented ones, and beneficial activities may help the future researchers to derive a conclusion on its beneficial effects on health.
130 citations
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TL;DR: This article investigated L2 writing teachers' perspectives, practices and problems regarding error feedback and found that although selective marking is recommended both in the local English syllabus and error correction literature, the majority of teachers tend to treat error feedback as a job with little longterm significance.
130 citations
Authors
Showing all 7946 results
Name | H-index | Papers | Citations |
---|---|---|---|
Weihong Tan | 140 | 892 | 67151 |
Bin Liu | 138 | 2181 | 87085 |
Jun Lu | 135 | 1526 | 99767 |
John P. Giesy | 114 | 1162 | 62790 |
Qiang Yang | 112 | 1117 | 71540 |
Ming Hung Wong | 103 | 710 | 39738 |
Wei Wang | 95 | 3544 | 59660 |
Jianhua Zhang | 92 | 415 | 28085 |
Xiaojun Wu | 91 | 1088 | 31687 |
Guibin Jiang | 88 | 850 | 34633 |
Shu Tao | 87 | 639 | 27304 |
Paul K.S. Lam | 87 | 485 | 25614 |
Cheng-Yong Su | 87 | 581 | 32322 |
Hai-Long Jiang | 86 | 198 | 30946 |
Baowen Li | 83 | 477 | 23080 |