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Institution

Hong Kong Baptist University

EducationHong Kong, China
About: Hong Kong Baptist University is a education organization based out in Hong Kong, China. It is known for research contribution in the topics: Population & China. The organization has 7811 authors who have published 18919 publications receiving 555274 citations. The organization is also known as: Hong Kong Baptist College & HKBU.


Papers
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Journal ArticleDOI
TL;DR: The rod-like tetragonal α-MnO 2, flower-like hexagonal ǫ nO 2 and dumbbell-like β-mnO2 were obtained using the hydrothermal or water-bathing method under different conditions as discussed by the authors.
Abstract: The rod-like tetragonal α-MnO 2 , flower-like hexagonal ɛ-MnO 2 , and dumbbell-like tetragonal β-MnO 2 were prepared using the hydrothermal or water-bathing method under different conditions. It is shown that the α-MnO 2 , ɛ-MnO 2 , and β-MnO 2 catalysts possessed a surface area of ca. 53, 30, and 114 m 2 /g, respectively. The oxygen adspecies concentration and low-temperature reducibility decreased in the order of α-MnO 2 > ɛ-MnO 2 > β-MnO 2 , coinciding with the sequence of their catalytic activities for toluene combustion. The well-defined morphological MnO 2 catalysts performed much better than the bulk counterpart. At a space velocity of 20,000 mL/(g h), the temperature for 90% toluene conversion was 238, 229, and 241 °C over α-MnO 2 , ɛ-MnO 2 , and β-MnO 2 , respectively. The apparent activation energies of α-MnO 2 , ɛ-MnO 2 , and β-MnO 2 were in the range of 20–26 kJ/mol. It is concluded that higher oxygen adspecies concentrations and better low-temperature reducibility were responsible for the good catalytic performance of the α-MnO 2 , ɛ-MnO 2 , and β-MnO 2 materials.

128 citations

Journal ArticleDOI
TL;DR: The effects of brief, intense exercise in comparison with traditional endurance exercise on both novel and traditional markers of cardiovascular disease (CVD) in youth are examined.
Abstract: This article was published in American Journal of Human Biology on 4 April 2011 (online), available at http://dx.doi.org/10.1002/ajhb.21166

128 citations

Journal ArticleDOI
06 Apr 2018-Science
TL;DR: Aspects of Acheulean technology in this region imply that, as early as 615,000 years ago, greater stone material selectivity and wider resource procurement coincided with an increased pace of land-lake fluctuation, potentially anticipating the adaptability of MSA hominins.
Abstract: Development of the African Middle Stone Age (MSA) before 300,000 years ago raises the question of how environmental change influenced the evolution of behaviors characteristic of early Homo sapiens . We used temporally well-constrained sedimentological and paleoenvironmental data to investigate environmental dynamics before and after the appearance of the early MSA in the Olorgesailie basin, Kenya. In contrast to the Acheulean archeological record in the same basin, MSA sites are associated with a markedly different faunal community, more pronounced erosion-deposition cycles, tectonic activity, and enhanced wet-dry variability. Aspects of Acheulean technology in this region imply that, as early as 615,000 years ago, greater stone material selectivity and wider resource procurement coincided with an increased pace of land-lake fluctuation, potentially anticipating the adaptability of MSA hominins.

128 citations

Journal ArticleDOI
TL;DR: This review will summarize recent advances regarding the roles of mTOR and autophagy in PD pathogenesis and treatment and suggest that characterizing the dysregulation of the mTOR pathway and the clinical translation of m TOR modulators in PD may offer exciting new avenues for future drug development.
Abstract: The mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in regulating cell growth, proliferation, and life span. mTOR signaling is a central regulator of autophagy by modulating multiple aspects of the autophagy process, such as initiation, process, and termination through controlling the activity of the unc51-like kinase 1 (ULK1) complex and vacuolar protein sorting 34 (VPS34) complex, and the intracellular distribution of TFEB/TFE3 and proto-lysosome tubule reformation. Parkinson’s disease (PD) is a serious, common neurodegenerative disease characterized by dopaminergic neuron loss in the substantia nigra pars compacta (SNpc) and the accumulation of Lewy bodies. An increasing amount of evidence indicates that mTOR and autophagy are critical for the pathogenesis of PD. In this review, we will summarize recent advances regarding the roles of mTOR and autophagy in PD pathogenesis and treatment. Further characterizing the dysregulation of mTOR pathway and the clinical translation of mTOR modulators in PD may offer exciting new avenues for future drug development.

128 citations

Journal ArticleDOI
TL;DR: This mini-review highlights recent examples of the use of molecular docking in virtual screening for the identification of bioactive molecules from natural product databases.
Abstract: Molecular docking enables the extraordinary structural diversity of natural products to be harnessed in an efficient manner. In this mini-review, we highlight recent examples of the use of molecular docking in virtual screening for the identification of bioactive molecules from natural product databases.

128 citations


Authors

Showing all 7946 results

NameH-indexPapersCitations
Weihong Tan14089267151
Bin Liu138218187085
Jun Lu135152699767
John P. Giesy114116262790
Qiang Yang112111771540
Ming Hung Wong10371039738
Wei Wang95354459660
Jianhua Zhang9241528085
Xiaojun Wu91108831687
Guibin Jiang8885034633
Shu Tao8763927304
Paul K.S. Lam8748525614
Cheng-Yong Su8758132322
Hai-Long Jiang8619830946
Baowen Li8347723080
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202346
2022246
20211,655
20201,479
20191,244
20181,093