Hong Kong Baptist University

About: Hong Kong Baptist University is a education organization based out in Hong Kong, China. It is known for research contribution in the topics: Population & China. The organization has 7811 authors who have published 18919 publications receiving 555274 citations. The organization is also known as: Hong Kong Baptist College & HKBU.

Enhanced efficiency of polymer solar cells by adding a high-mobility conjugated polymer

Abstract: The performance of organic solar cells is substantially enhanced by introducing high-mobility conjugate polymers as additives for the first time. The most pronounced effect is observed in one type of device with the average power conversion efficiencies increased from 8.75% to 10.08% after the addition of a high-mobility polymer for only 0.5 weight percent in the active layers, which is mainly attributed to the increased hole mobility and carrier lifetime in the devices. Besides the hole mobility, the energy band structure of the additive is also found to be critical to the enhancement of the device performance. This work demonstrates a novel approach for improving the efficiencies of organic solar cells.

Large-Pore Mesoporous-Silica-Coated Upconversion Nanoparticles as Multifunctional Immunoadjuvants with Ultrahigh Photosensitizer and Antigen Loading Efficiency for Improved Cancer Photodynamic Immunotherapy

Abstract: Reported immunoadjuvants still have many limitations, such as inferior cellular uptake capacity and biocompatibility, overly large particle sizes, single function, and unsatisfactory therapeutic efficacy. Here, large-pore mesoporous-silica-coated upconversion nanoparticles (UCMSs) with a size of less than 100 nm are successfully prepared by a typical silica sol-gel reaction using mesitylene as a pore-swelling agent and are applied as a novel immunoadjuvant. The obtained UCMSs not only show significantly higher loadings for the photosensitizers merocyanine 540 (MC540), model proteins (chicken ovalbumin (OVA)), and tumor antigens (tumor cell fragment (TF)), but also are successfully employed for highly efficient in vivo vaccine delivery. The prepared UCMSs-MC540-OVA under 980 nm near-infrared irradiation shows the best synergistic immunopotentiation action, verified by the strongest Th1 and Th2 immune responses and the highest frequency of CD4+ , CD8+ , and effector-memory T cells. Additionally, nanovaccines UCMSs-MC540-TF can more effectively inhibit tumor growth and increase the survival of colon cancer (CT26)-tumor-bearing BALB/c mice compared with either photodynamic therapy or immunological therapy alone, suggesting the enhanced immunotherapy efficacy and clinical potential of UCMSs as immunoadjuvants for cancer immunotherapy.

A simultaneous redox, alkylation, self-assembly reaction under solvothermal conditions afforded a luminescent copper(I) chain polymer constructed of Cu3I4- and EtS-4-C5H4N+Et components (Et = CH3CH2).

Abstract: A simultaneous redox, alkylation, self-assembly reaction under solvothermal conditions afforded a novel copper(I) chain polymer constructed of luminescent Cu3I4- and unprecedented EtS-4-C5H4N+Et components (Et = CH3CH2).