Institution
Hospital General Universitario Gregorio Marañón
Healthcare•Madrid, Spain•
About: Hospital General Universitario Gregorio Marañón is a healthcare organization based out in Madrid, Spain. It is known for research contribution in the topics: Population & Transplantation. The organization has 11975 authors who have published 12386 publications receiving 244847 citations.
Topics: Population, Transplantation, Myocardial infarction, Intensive care, COPD
Papers published on a yearly basis
Papers
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TL;DR: A moderate to high prevalence of potentially modifiable risk factors for UE is found, suggesting unsatisfactory ICU practices, and the highest rates of UE previously reported in orally intubated medical patients in the ICU or the association with mortality are not confirmed.
77 citations
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TL;DR: "Less aggressive" burst stimulation is more effective in terminating spontaneous monomorphic ventricular tachycardia with a lesser acceleration rate.
Abstract: "Less aggressive" burst stimulation is more effective in terminating spontaneous monomorphic ventricular tachycardia with a lesser acceleration rate. Higher ventricular tachycardia cycle length and use of 91% coupling interval were independent predictors for pacing termination.
77 citations
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TL;DR: The superiority of FEC-P over FEC was clearly more marked in HR−/HER2− patients (TN patients), particularly in the subset with basal phenotype (TN and either EGFR+ or cytokeratins 5/6+).
Abstract: Treatment with fluororacil, epirubicin, and cyclophosphamide followed by weekly paclitaxel (FEC-P) yielded superior disease-free survival than FEC in the adjuvant breast cancer trial GEICAM 9906. We evaluate molecular subtypes predictive of prognosis and paclitaxel response in this trial. Two molecular subtype classifications based on conventional immunohistochemical and fluorescent in situ hybridization determinations were used: #1: Four groups segregated according to the combination of hormone receptor (HR) and HER2 status; #2: Intrinsic subtype classification (Triple Negative (TN), HER2, Luminal B and Luminal A). Results: Both subtype classifications yielded prognostic and predictive information. HR +/HER2− patients (and Luminal A patients) had a significantly better outcome than the other subgroups of patients. The superiority of FEC-P over FEC was clearly more marked in HR−/HER2− patients (TN patients), particularly in the subset with basal phenotype (TN and either EGFR+ or cytokeratins 5/6+). The Luminal A subtype also achieved a significant benefit with FEC-P. The molecular-defined subgroup of TN was clearly predictive of better response to treatment with FEC-P. Luminal A patients had the best prognosis and also have a better outcome with weekly paclitaxel.
77 citations
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TL;DR: El nuevo modelo organizativo sanitario del PASI debe hacer hincapie en las caracteristicas de los diferentes niveles asistenciales con la potenciacion de Hospitales de Referencia, establecer nuevos criterios de activacion del Codigo Ictus menos restrictivos that contemplen las nuevas posibilidades terapeutic
Abstract: Resumen Introduccion El Grupo de Estudio de Enfermedades Cerebrovasculares de la Sociedad Espanola de Neurologia publico en el ano 2006 el Plan de Atencion Sanitaria del Ictus (PASI) con el objetivo de elaborar un sistema organizado de atencion al ictus que de respuesta a las necesidades de cada enfermo y optimice la utilizacion de los recursos sanitarios. Este plan pretendia garantizar la equidad en la atencion sanitaria del paciente con ictus. La Estrategia Nacional en Ictus del Sistema Nacional de Salud aprobada en el ano 2008 recogio en gran medida el tipo de modelo organizativo sanitario del PASI. Sin embargo, en el tiempo transcurrido desde su publicacion, han aparecido nuevos avances en el tratamiento de la fase aguda del infarto cerebral que obligan a realizar una revision del mismo. Fuentes Un comite de 19 neurologos especialistas en patologia neurovascular y representativos de las diferentes comunidades autonomas han revisado el PASI con el objetivo de incorporar los nuevos avances del tratamiento en la fase aguda del infarto cerebral. Esta revision se ha basado en una revision de la literatura cientifica y en la experiencia acumulada con el plan anterior. Desarrollo El nuevo modelo organizativo propuesto debe hacer hincapie en las caracteristicas de los diferentes niveles asistenciales con la potenciacion de Hospitales de Referencia, establecer nuevos criterios de activacion del Codigo Ictus menos restrictivos que contemplen las nuevas posibilidades terapeuticas, establecer medidas organizativas para la implantacion del intervencionismo neurovascular y permitir la utilizacion del recurso tecnico de la telemedicina.
77 citations
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TL;DR: The prognostic power of these factors in the published literature is too low to advocate their routine use in clinical practice and to drive the choice on adjuvant treatment in clinical stage I seminoma testis patients.
76 citations
Authors
Showing all 12014 results
Name | H-index | Papers | Citations |
---|---|---|---|
David H. Adams | 155 | 1613 | 117783 |
Stefanie Dimmeler | 147 | 574 | 81658 |
Stuart J. Pocock | 145 | 684 | 143547 |
M. I. Martínez | 134 | 1251 | 79885 |
Guy A. Rouleau | 129 | 884 | 65892 |
Jose L. Jimenez | 124 | 654 | 64226 |
Antoni Torres | 120 | 1238 | 65049 |
Paul P. Tak | 112 | 591 | 57689 |
Luis A. Diaz | 111 | 596 | 75036 |
Frans Van de Werf | 109 | 747 | 63537 |
José Luis Zamorano | 105 | 695 | 133396 |
Francisco Sánchez-Madrid | 102 | 527 | 43418 |
Francesco Locatelli | 99 | 820 | 42454 |
Roberto M. Lang | 96 | 823 | 56638 |
Carlos Simón | 95 | 589 | 31147 |