Institution
Humboldt University of Berlin
Education•Berlin, Germany•
About: Humboldt University of Berlin is a education organization based out in Berlin, Germany. It is known for research contribution in the topics: Population & Transplantation. The organization has 33671 authors who have published 61781 publications receiving 1908102 citations. The organization is also known as: Humboldt-Universität zu Berlin & Universitas Humboldtiana Berolinensis.
Papers published on a yearly basis
Papers
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TL;DR: The sensitivity of MALDI-TOF MS is demonstrated regarding the adaption of the chemical composition of three Poaceae (grass) pollen for different populations of parent plants by analyzing the mass spectra with partial least squares discriminant analysis (PLS-DA) and principal component analysis (PCA).
Abstract: MALDI time-of-flight mass spectrometry (MALDI-TOF MS) has become a widely used tool for the classification of biological samples. The complex chemical composition of pollen grains leads to highly specific, fingerprint-like mass spectra, with respect to the pollen species. Beyond the species-specific composition, the variances in pollen chemistry can be hierarchically structured, including the level of different populations, of environmental conditions or different genotypes. We demonstrate here the sensitivity of MALDI-TOF MS regarding the adaption of the chemical composition of three Poaceae (grass) pollen for different populations of parent plants by analyzing the mass spectra with partial least squares discriminant analysis (PLS-DA) and principal component analysis (PCA). Thereby, variances in species, population and specific growth conditions of the plants were observed simultaneously. In particular, the chemical pattern revealed by the MALDI spectra enabled discrimination of the different populations of one species. Specifically, the role of environmental changes and their effect on the pollen chemistry of three different grass species is discussed. Analysis of the group formation within the respective populations showed a varying influence of plant genotype on the classification, depending on the species, and permits conclusions regarding the respective rigidity or plasticity towards environmental changes.
360 citations
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TL;DR: An unusual intronless gene on chromosome 5q23.1 is reported that encodes a 242-amino acid precursor of a ferritin H-like protein that accumulates in high amounts in iron-loaded mitochondria of erythroblasts of subjects with impaired heme synthesis and may play an important role in the regulation of mitochondrial iron homeostasis andHeme synthesis.
360 citations
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TL;DR: In this article, the authors investigate the effect of digitalization on energy consumption using an analytical model, and investigate four effects: (1) direct effects from the production, usage and disposal of information and communication technologies (ICT), (2) energy efficiency increases from digitalization, (3) economic growth from increases in labor and energy productivities and (4) sectoral change/tertiarization from the rise of ICT services.
360 citations
01 Dec 2011
TL;DR: In this article, the convergence of molecular engineering and genomic discovery for the utilization and understanding of light-activated ion channels and pumps has been explored, and a group of microbial opsins bridging prior categories is described.
Abstract: The capture and utilization of light is an exquisitely evolved process. The single-component microbial opsins, although more limited than multicomponent cascades in processing, display unparalleled compactness and speed. Recent advances in understanding microbial opsins have been driven by molecular engineering for optogenetics and by comparative genomics. Here we provide a Primer on these light-activated ion channels and pumps, describe a group of opsins bridging prior categories, and explore the convergence of molecular engineering and genomic discovery for the utilization and understanding of these remarkable molecular machines.
360 citations
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TL;DR: This paper looks for strategies which minimize the shortfall risk defined as the expectation of the shortfall weighted by some loss function, and determined quantile hedges which succeed with maximal probability, given a capital constraint.
Abstract: An investor faced with a contingent claim may eliminate risk by (super-) hedging in a financial market. As this is often quite expensive, we study partial hedges which require less capital and reduce the risk. In a previous paper we determined quantile hedges which succeed with maximal probability, given a capital constraint. Here we look for strategies which minimize the shortfall risk defined as the expectation of the shortfall weighted by some loss function. The resulting efficient hedges allow the investor to interpolate in a systematic way between the extremes of no hedge and a perfect (super-) hedge, depending on the accepted level of shortfall risk.
360 citations
Authors
Showing all 34115 results
Name | H-index | Papers | Citations |
---|---|---|---|
Karl J. Friston | 217 | 1267 | 217169 |
Peer Bork | 206 | 697 | 245427 |
Raymond J. Dolan | 196 | 919 | 138540 |
Stefan Schreiber | 178 | 1233 | 138528 |
Andreas Pfeiffer | 149 | 1756 | 131080 |
Thomas Hebbeker | 148 | 1984 | 114004 |
Thomas Lohse | 148 | 1237 | 101631 |
Jean Bousquet | 145 | 1288 | 96769 |
Hermann Kolanoski | 145 | 1279 | 96152 |
Josh Moss | 139 | 1019 | 89255 |
R. D. Kass | 138 | 1920 | 107907 |
W. Kozanecki | 138 | 1498 | 99758 |
U. Mallik | 137 | 1625 | 97439 |
C. Haber | 135 | 1507 | 98014 |
Christophe Royon | 134 | 1453 | 90249 |