Humboldt University of Berlin

About: Humboldt University of Berlin is a education organization based out in Berlin, Germany. It is known for research contribution in the topics: Population & Transplantation. The organization has 33671 authors who have published 61781 publications receiving 1908102 citations. The organization is also known as: Humboldt-Universität zu Berlin & Universitas Humboldtiana Berolinensis.

Measurement of the muon reconstruction performance of the ATLAS detector using 2011 and 2012 LHC proton-proton collision data

Abstract: This paper presents the performance of the ATLAS muon reconstruction during the LHC run with pp collisions at root s = 7-8 TeV in 2011-2012, focusing mainly on data collected in 2012. Measurements ...

Parameterized Complexity and Approximation Algorithms

Abstract: Approximation algorithms and parameterized complexity are usually considered to be two separate ways of dealing with hard algorithmic problems. In this paper, our aim is to investigate how these two fields can be combined to achieve better algorithms than what any of the two theories could offer. We discuss the different ways parameterized complexity can be extended to approximation algorithms, survey results of this type and propose directions for future research.

Persistent Differences Among Centers Over 3 Years in Glycemic Control and Hypoglycemia in a Study of 3,805 Children and Adolescents With Type 1 Diabetes From the Hvidøre Study Group

Abstract: OBJECTIVE —Twenty-one international pediatric diabetes centers from 17 countries investigated the effect of simple feedback about the grand mean HbA 1c level of all centers and the average value of each center on changes in metabolic control, rate of severe hypoglycemia, and insulin therapy over a 3-year period. RESEARCH DESIGN AND METHODS —Clinical data collection and determination of HbA 1c levels were conducted at a central location in 1995 ( n = 2,780, age 0–18 years) and 1998 ( n = 2,101, age 11–18 years). RESULTS —Striking differences in average HbA 1c concentrations were found among centers; these differences remained after adjustment for the significant confounders of sex, age, and diabetes duration. They were apparent even in patients with short diabetes duration and remained stable 3 years later (mean adjusted HbA 1c level: 8.62 ± 0.03 vs. 8.67 ± 0.04 [1995 vs. 1998, respectively]). Three centers had improved significantly, four centers had deteriorated significantly in their overall adjusted HbA 1c levels, and 14 centers had not changed in glycemic control. During the observation period, there were increases in the adjusted insulin dose by 0.076 U/kg, the adjusted number of injections by 0.23 injections per day, and the adjusted BMI by 0.95 kg/m 2 . The 1995 versus 1998 difference in glycemic control for the seven centers could not be explained by prevailing insulin regimens or rates of hypoglycemia. CONCLUSIONS —This study reveals significant outcome differences among large international pediatric diabetes centers. Feedback and comparison of HbA 1c levels led to an intensification of insulin therapy in most centers, but improved glycemic control in only a few.