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Institution

Hungarian Academy of Sciences

GovernmentBudapest, Hungary
About: Hungarian Academy of Sciences is a government organization based out in Budapest, Hungary. It is known for research contribution in the topics: Catalysis & Population. The organization has 21510 authors who have published 56712 publications receiving 1612286 citations. The organization is also known as: Magyar Tudományos Akadémia & MTA.
Topics: Catalysis, Population, Adsorption, Neutron, Ionization


Papers
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Journal ArticleDOI
TL;DR: The IUPred server presents a novel algorithm for predicting such regions from amino acid sequences by estimating their total pairwise interresidue interaction energy, based on the assumption that IUP sequences do not fold due to their inability to form sufficient stabilizing inter Residue interactions.
Abstract: Summary: Intrinsically unstructured/disordered proteins and domains (IUPs) lack a well-defined three-dimensional structure under native conditions. The IUPred server presents a novel algorithm for predicting such regions from amino acid sequences by estimating their total pairwise interresidue interaction energy, based on the assumption that IUP sequences do not fold due to their inability to form sufficient stabilizing interresidue interactions. Optional to the prediction are built-in parameter sets optimized for predicting short or long disordered regions and structured domains. Availability: The IUPred server is available for academic users at http://iupred.enzim.hu Contact: [email protected]

1,954 citations

Journal ArticleDOI
27 May 2011-Science
TL;DR: The differences across cultures in the enforcement of conformity may reflect their specific histories and advances knowledge that can foster cross-cultural understanding in a world of increasing global interdependence and has implications for modeling cultural change.
Abstract: With data from 33 nations, we illustrate the differences between cultures that are tight (have many strong norms and a low tolerance of deviant behavior) versus loose (have weak social norms and a high tolerance of deviant behavior). Tightness-looseness is part of a complex, loosely integrated multilevel system that comprises distal ecological and historical threats (e.g., high population density, resource scarcity, a history of territorial conflict, and disease and environmental threats), broad versus narrow socialization in societal institutions (e.g., autocracy, media regulations), the strength of everyday recurring situations, and micro-level psychological affordances (e.g., prevention self-guides, high regulatory strength, need for structure). This research advances knowledge that can foster cross-cultural understanding in a world of increasing global interdependence and has implications for modeling cultural change.

1,895 citations

Journal ArticleDOI
TL;DR: The user is allowed to submit additional information about segment localization to enhance the prediction power, which improves the prediction accuracy as well as helps the interpretation of experimental results, i.e. in epitope insertion experiments.
Abstract: Summary: The HMMTOP transmembrane topology prediction server predicts both the localization of helical transmembrane segments and the topology of transmembrane proteins. Recently, several improvements have been introduced to the original method. Now, the user is allowed to submit additional information about segment localization to enhance the prediction power. This option improves the prediction accuracy as well as helps the interpretation of experimental results, i.e. in epitope insertion experiments. Availability: HMMTOP 2.0 is freely available to noncommercial users at http://www.enzim.hu/hmmtop. Source code is also available upon request to academic users.

1,866 citations

Book ChapterDOI
TL;DR: This chapter is dedicated to describing citrate synthase, which can be followed by measuring the appearance of the free SH group of the released CoASH through three methods discussed in the chapter.
Abstract: Publisher Summary This chapter is dedicated to describing citrate synthase. The assay of citrate synthase is performed by coupling it to the transacetylase reaction. The disappearance of acetyl phosphate is followed by a hydroxamate method and the formation of citrate by the pentabromoacetone method. The malate dehydrogenase catalyzed reaction is used to generate the oxaloacetate for the citrate synthase reaction. Another method for assaying citrate synthase uses 14 C-acetyl-CoA and measures its incorporation in 14 C-citrate, which is isolated as a silver salt. Citrate synthase can be followed by measuring the appearance of the free SH group of the released CoASH; three such methods are discussed in the chapter. One method is to measure the oxidation of the CoASH by dichlorophenol- indophenol, which is accompanied by a decrease in absorbancy at 578 mμ. Another method measures the CoASH polarographically. The third method measures SH by the use of 5, 5’-dithiobis-(2-nitrobenzoate) (DTNB) (Ellman's reagent).

1,848 citations


Authors

Showing all 21526 results

NameH-indexPapersCitations
Jasvinder A. Singh1762382223370
Alexander S. Szalay166936145745
Ashok Kumar1515654164086
György Buzsáki15044696433
Daniel Bloch1451819119556
Brajesh C Choudhary1431618108058
Geoffrey Burnstock141148899525
Suman Bala Beri1371608104798
Vipin Bhatnagar1371756104163
Paul Slovic136506126658
Manjit Kaur135154097378
Gabor Istvan Veres135134996104
Dimitri Bourilkov134148996884
Georges Azuelos134129490690
Michael Tytgat134144994133
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20238
202247
2021584
20201,033
20192,029
20182,015