Institution
IBM
Company•Armonk, New York, United States•
About: IBM is a company organization based out in Armonk, New York, United States. It is known for research contribution in the topics: Layer (electronics) & Cache. The organization has 134567 authors who have published 253905 publications receiving 7458795 citations. The organization is also known as: International Business Machines Corporation & Big Blue.
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IBM1
TL;DR: In this article, two genuinely quantum models for an antiferromagnetic linear chain with nearest neighbor interactions are constructed and solved exactly, in the sense that the ground state, all the elementary excitations and the free energy are found.
3,382 citations
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TL;DR: It is shown that the tumour type is characterized by complex genomic alterations, with a mean of 360 exonic mutations, 165 genomic rearrangements, and 323 segments of copy number alteration per tumour.
Abstract: Lung squamous cell carcinoma is a common type of lung cancer, causing approximately 400,000 deaths per year worldwide. Genomic alterations in squamous cell lung cancers have not been comprehensively characterized, and no molecularly targeted agents have been specifically developed for its treatment. As part of The Cancer Genome Atlas, here we profile 178 lung squamous cell carcinomas to provide a comprehensive landscape of genomic and epigenomic alterations. We show that the tumour type is characterized by complex genomic alterations, with a mean of 360 exonic mutations, 165 genomic rearrangements, and 323 segments of copy number alteration per tumour. We find statistically recurrent mutations in 11 genes, including mutation of TP53 in nearly all specimens. Previously unreported loss-of-function mutations are seen in the HLA-A class I major histocompatibility gene. Significantly altered pathways included NFE2L2 and KEAP1 in 34%, squamous differentiation genes in 44%, phosphatidylinositol-3-OH kinase pathway genes in 47%, and CDKN2A and RB1 in 72% of tumours. We identified a potential therapeutic target in most tumours, offering new avenues of investigation for the treatment of squamous cell lung cancers.
3,356 citations
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IBM1
TL;DR: This work addresses the problem of predicting a word from previous words in a sample of text and discusses n-gram models based on classes of words, finding that these models are able to extract classes that have the flavor of either syntactically based groupings or semanticallybased groupings, depending on the nature of the underlying statistics.
Abstract: We address the problem of predicting a word from previous words in a sample of text. In particular, we discuss n-gram models based on classes of words. We also discuss several statistical algorithms for assigning words to classes based on the frequency of their co-occurrence with other words. We find that we are able to extract classes that have the flavor of either syntactically based groupings or semantically based groupings, depending on the nature of the underlying statistics.
3,336 citations
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TL;DR: Inspired by the brain’s structure, an efficient, scalable, and flexible non–von Neumann architecture is developed that leverages contemporary silicon technology and is well suited to many applications that use complex neural networks in real time, for example, multiobject detection and classification.
Abstract: Inspired by the brain’s structure, we have developed an efficient, scalable, and flexible non–von Neumann architecture that leverages contemporary silicon technology. To demonstrate, we built a 5.4-billion-transistor chip with 4096 neurosynaptic cores interconnected via an intrachip network that integrates 1 million programmable spiking neurons and 256 million configurable synapses. Chips can be tiled in two dimensions via an interchip communication interface, seamlessly scaling the architecture to a cortexlike sheet of arbitrary size. The architecture is well suited to many applications that use complex neural networks in real time, for example, multiobject detection and classification. With 400-pixel-by-240-pixel video input at 30 frames per second, the chip consumes 63 milliwatts.
3,253 citations
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IBM1
TL;DR: As-synthesized iron oxide nanoparticles have a cubic spinel structure as characterized by HRTEM, SAED, and XRD and can be transformed into hydrophilic ones by adding bipolar surfactants, and aqueous nanoparticle dispersion is readily made.
Abstract: High-temperature solution phase reaction of iron(III) acetylacetonate, Fe(acac)3, with 1,2-hexadecanediol in the presence of oleic acid and oleylamine leads to monodisperse magnetite (Fe3O4) nanoparticles. Similarly, reaction of Fe(acac)3 and Co(acac)2 or Mn(acac)2 with the same diol results in monodisperse CoFe2O4 or MnFe2O4 nanoparticles. Particle diameter can be tuned from 3 to 20 nm by varying reaction conditions or by seed-mediated growth. The as-synthesized iron oxide nanoparticles have a cubic spinel structure as characterized by HRTEM, SAED, and XRD. Further, Fe3O4 can be oxidized to Fe2O3, as evidenced by XRD, NEXAFS spectroscopy, and SQUID magnetometry. The hydrophobic nanoparticles can be transformed into hydrophilic ones by adding bipolar surfactants, and aqueous nanoparticle dispersion is readily made. These iron oxide nanoparticles and their dispersions in various media have great potential in magnetic nanodevice and biomagnetic applications.
3,244 citations
Authors
Showing all 134658 results
Name | H-index | Papers | Citations |
---|---|---|---|
Zhong Lin Wang | 245 | 2529 | 259003 |
Anil K. Jain | 183 | 1016 | 192151 |
Hyun-Chul Kim | 176 | 4076 | 183227 |
Rodney S. Ruoff | 164 | 666 | 194902 |
Tobin J. Marks | 159 | 1621 | 111604 |
Jean M. J. Fréchet | 154 | 726 | 90295 |
Albert-László Barabási | 152 | 438 | 200119 |
György Buzsáki | 150 | 446 | 96433 |
Stanislas Dehaene | 149 | 456 | 86539 |
Philip S. Yu | 148 | 1914 | 107374 |
James M. Tour | 143 | 859 | 91364 |
Thomas P. Russell | 141 | 1012 | 80055 |
Naomi J. Halas | 140 | 435 | 82040 |
Steven G. Louie | 137 | 777 | 88794 |
Daphne Koller | 135 | 367 | 71073 |