IBM

About: IBM is a company organization based out in Armonk, New York, United States. It is known for research contribution in the topics: Layer (electronics) & Cache. The organization has 134567 authors who have published 253905 publications receiving 7458795 citations. The organization is also known as: International Business Machines Corporation & Big Blue.

Development of an improved four-site water model for biomolecular simulations: TIP4P-Ew

Abstract: A re-parameterization of the standard TIP4P water model for use with Ewald techniques is introduced, providing an overall global improvement in water properties relative to several popular nonpolarizable and polarizable water potentials. Using high precision simulations, and careful application of standard analytical corrections, we show that the new TIP4P-Ew potential has a density maximum at approximately 1 degrees C, and reproduces experimental bulk-densities and the enthalpy of vaporization, DeltaH(vap), from -37.5 to 127 degrees C at 1 atm with an absolute average error of less than 1%. Structural properties are in very good agreement with x-ray scattering intensities at temperatures between 0 and 77 degrees C and dynamical properties such as self-diffusion coefficient are in excellent agreement with experiment. The parameterization approach used can be easily generalized to rehabilitate any water force field using available experimental data over a range of thermodynamic points.

Translating biomolecular recognition into nanomechanics.

Abstract: We report the specific transduction, via surface stress changes, of DNA hybridization and receptor-ligand binding into a direct nanomechanical response of microfabricated cantilevers. Cantilevers in an array were functionalized with a selection of biomolecules. The differential deflection of the cantilevers was found to provide a true molecular recognition signal despite large nonspecific responses of individual cantilevers. Hybridization of complementary oligonucleotides shows that a single base mismatch between two 12-mer oligonucleotides is clearly detectable. Similar experiments on protein A-immunoglobulin interactions demonstrate the wide-ranging applicability of nanomechanical transduction to detect biomolecular recognition.

The Physical Implementation of Quantum Computation

Abstract: After a brief introduction to the principles and promise of quantum information processing, the requirements for the physical implementation of quantum computation are discussed. These five requirements, plus two relating to the communication of quantum information, are extensively ex- plored and related to the many schemes in atomic physics, quantum optics, nuclear and electron magnetic resonance spectroscopy, superconducting electronics, and quantum-dot physics, for achiev- ing quantum computing. I. INTRODUCTION � The advent of quantum information processing, as an abstract concept, has given birth to a great deal of new thinking, of a very concrete form, about how to create physical computing devices that operate in the hitherto unexplored quantum mechanical regime. The efforts now underway to produce working laboratory devices that perform this profoundly new form of information pro- cessing are the subject of this book. In this chapter I provide an overview of the common objectives of the investigations reported in the remain- der of this special issue. The scope of the approaches, proposed and underway, to the implementation of quan- tum hardware is remarkable, emerging from specialties in atomic physics (1), in quantum optics (2), in nuclear (3) and electron (4) magnetic resonance spectroscopy, in su- perconducting device physics (5), in electron physics (6), and in mesoscopic and quantum dot research (7). This amazing variety of approaches has arisen because, as we will see, the principles of quantum computing are posed using the most fundamental ideas of quantum mechanics, ones whose embodiment can be contemplated in virtually every branch of quantum physics. The interdisciplinary spirit which has been fostered as a result is one of the most pleasant and remarkable fea- tures of this field. The excitement and freshness that has been produced bodes well for the prospect for discovery, invention, and innovation in this endeavor.

What is "liquid"? Understanding the states of matter

Abstract: Liquids exist in a relatively small part of the enormous range of temperatures and pressures existing in the universe. Nevertheless, they are of vital importance for physics and chemistry, for technology, and for life itself. A century of effort since the pioneering work of van der Waals has led to a fairly complete basic understanding of the static and dynamic physicochemical properties of liquids. Advances in statistical mechanics (the fundamental formulations of Gibbs and Boltzmann, integral equations and perturbation theories, computer simulations), in knowledge of intermolecular forces, and in experimental techniques; have all contributed to this. Thirty years ago the very existence of liquids seemed a little mysterious; today one can make fairly precise predictions of the solid-liquid-gas phase diagram and of the microscopic and macroscopic static and dynamic properties of liquids. This paper is a survey, with particular emphasis on equilibrium properties, of the theory which underlies that basic understanding, which is now at least comparable with our understanding of the physics of solids.

Enhancing security and privacy in biometrics-based authentication systems

Abstract: Because biometrics-based authentication offers several advantages over other authentication methods, there has been a significant surge in the use of biometrics for user authentication in recent years. It is important that such biometrics-based authentication systems be designed to withstand attacks when employed in security-critical applications, especially in unattended remote applications such as e-commerce. In this paper we outline the inherent strengths of biometrics-based authentication, identify the weak links in systems employing biometrics-based authentication, and present new solutions for eliminating some of these weak links. Although, for illustration purposes, fingerprint authentication is used throughout, our analysis extends to other biometrics-based methods.