Institution
Icahn School of Medicine at Mount Sinai
Education•New York, New York, United States•
About: Icahn School of Medicine at Mount Sinai is a education organization based out in New York, New York, United States. It is known for research contribution in the topics: Population & Cancer. The organization has 37488 authors who have published 76057 publications receiving 3704104 citations. The organization is also known as: Mount Sinai School of Medicine.
Topics: Population, Cancer, Transplantation, Virus, Health care
Papers published on a yearly basis
Papers
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TL;DR: It is suggested that failure of the ubiquitin-proteasome system to adequately clear unwanted proteins may underlie vulnerability and degeneration of the SNc in both sporadic and familial PD.
586 citations
TL;DR: As of late March 2020, the global COVID-19 pandemic caused by the SARS-CoV-2 virus has battered the world and more than 40,000 people have died with over 800,000People confirmed infected.
Abstract: As of late March 2020, the global COVID-19 pandemic caused by the SARS-CoV-2 virus has battered the world. More than 40,000 people have died with over 800,000 people confirmed infected; financial m...
586 citations
Fredrick R. Schumacher1, Ali Amin Al Olama2, Sonja I. Berndt3, Sara Benlloch2 +204 more•Institutions (79)
TL;DR: A large meta-analysis combining genome-wide and custom high-density genotyping array data identifies 63 new susceptibility loci for prostate cancer, enhancing fine-mapping efforts and providing insights into the underlying biology of PrCa1.
Abstract: Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data from a custom high-density array of 46,939 PrCa cases and 27,910 controls of European ancestry with previously genotyped data of 32,255 PrCa cases and 33,202 controls of European ancestry. Our analysis identified 62 novel loci associated (P C, p.Pro1054Arg) in ATM and rs2066827 (OR = 1.06; P = 2.3 × 10−9; T>G, p.Val109Gly) in CDKN1B. The combination of all loci captured 28.4% of the PrCa familial relative risk, and a polygenic risk score conferred an elevated PrCa risk for men in the ninetieth to ninety-ninth percentiles (relative risk = 2.69; 95% confidence interval (CI): 2.55–2.82) and first percentile (relative risk = 5.71; 95% CI: 5.04–6.48) risk stratum compared with the population average. These findings improve risk prediction, enhance fine-mapping, and provide insight into the underlying biology of PrCa1. A large meta-analysis combining genome-wide and custom high-density genotyping array data identifies 63 new susceptibility loci for prostate cancer, enhancing fine-mapping efforts and providing insights into the underlying biology.
585 citations
TL;DR: The cognitive assessment protocol of the Alzheimer's Disease Cooperative Study (ADCS) was designed to evaluate the reliability and validity of cognitive assessment measures that might be valuable additions to the ADAS or other concise batteries used in a concise battery as discussed by the authors.
Abstract: SummaryThe cognitive assessment protocol of the Alzheimer's Disease Cooperative Study (ADCS) was designed to evaluate the reliability and validity of cognitive assessment measures that might be valuable additions to the Alzheimer's Disease Assessment Scale (ADAS) or other concise batteries used in a
585 citations
TL;DR: A factor analysis of the 90-item version of the Hopkins Symptom Checklist, performed on the pretreatment self-ratings of nonpsychotic outpatients with symptoms of depression and anxiety, revealed the presence of 8 clinically meaningful factors.
585 citations
Authors
Showing all 37948 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Robert Langer | 281 | 2324 | 326306 |
| Shizuo Akira | 261 | 1308 | 320561 |
| Gordon H. Guyatt | 231 | 1620 | 228631 |
| Eugene Braunwald | 230 | 1711 | 264576 |
| Bruce S. McEwen | 215 | 1163 | 200638 |
| Robert J. Lefkowitz | 214 | 860 | 147995 |
| Peter Libby | 211 | 932 | 182724 |
| Mark J. Daly | 204 | 763 | 304452 |
| Stuart H. Orkin | 186 | 715 | 112182 |
| Paul G. Richardson | 183 | 1533 | 155912 |
| Alan C. Evans | 183 | 866 | 134642 |
| John C. Morris | 183 | 1441 | 168413 |
| Paul M. Thompson | 183 | 2271 | 146736 |
| Tadamitsu Kishimoto | 181 | 1067 | 130860 |
| Bruce M. Psaty | 181 | 1205 | 138244 |