Institution
Indian Institute of Science Education and Research, Bhopal
Education•Bhopal, India•
About: Indian Institute of Science Education and Research, Bhopal is a education organization based out in Bhopal, India. It is known for research contribution in the topics: Catalysis & Enantioselective synthesis. The organization has 1100 authors who have published 1930 publications receiving 24749 citations. The organization is also known as: IISER & IISER-B.
Papers
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TL;DR: Results indicate that TRIM56 is an interferon-inducible E3 ubiquitin ligase that modulates STING to confer double-stranded DNA-mediated innate immune responses.
383 citations
Vardan Khachatryan1, Albert M. Sirunyan1, Armen Tumasyan1, Wolfgang Adam +2333 more•Institutions (195)
TL;DR: In this paper, the authors acknowledge the enduring support for the construction and operation of the LHC and the CMS detector provided by the following funding agencies:======BMWFW and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ,======And FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS======(Colombia); MSES and CSF (Croatia); RPF (
Abstract: we acknowledge the enduring support for the construction and
operation of the LHC and the CMS detector provided by the following funding agencies:
BMWFW and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ,
and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS
(Colombia); MSES and CSF (Croatia); RPF (Cyprus); SENESCYT (Ecuador);
MoER, ERC IUT and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland);
CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece);
OTKA and NIH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN
(Italy); MSIP and NRF (Republic of Korea); LAS (Lithuania); MOE and UM (Malaysia);
BUAP, CINVESTAV, CONACYT, LNS, SEP, and UASLP-FAI (Mexico); MBIE (New
Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna);
MON, RosAtom, RAS and RFBR (Russia); MESTD (Serbia); SEIDI and CPAN (Spain);
Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter, IPST, STAR and
NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU and SFFR (Ukraine); STFC
(United Kingdom); DOE and NSF (U.S.A.).
292 citations
TL;DR: This feature article has described reactions promoted by organocatalysts in a large excess of water, without any organic solvent or excess of any reactant.
268 citations
TL;DR: Current understanding of the biochemical and molecular properties, and pharmacological applications of ebselen and future directions in this area of research are summarized.
Abstract: Ebselen, an organoselenium compound, mimics glutathione peroxidase activity. It is a multifunctional compound, which catalyzes several essential reactions for the protection of cellular components from oxidative and free radical damage. Based on a number of in vitro and in vivo studies, various mechanisms are proposed to understand the biomedical actions of ebselen in health and diseases. It modulates metallo-proteins, enzymatic cofactors, gene expression, epigenetics, antioxidant defenses and immune systems. Owing to these properties, ebselen is currently under clinical trials for the prevention and treatment of various disorders such as cardiovascular diseases, arthritis, stroke, atherosclerosis, and cancer. A few ebselen-based pharmaceutical agents are under extensive investigation. As ebselen has been shown to have significant cellular toxicity, appropriate studies are needed to redesign the ebselen-based therapy for clinical trials. This review summarizes current understanding of the biochemical and molecular properties, and pharmacological applications of ebselen and future directions in this area of research.
249 citations
University of Tokyo1, Wellcome Trust Sanger Institute2, Liverpool School of Tropical Medicine3, University of Liverpool4, King Abdulaziz University5, Institut de recherche pour le développement6, Yale University7, Harvard University8, University of the Western Cape9, World Health Organization10, National Institute of Genetics11, Aberystwyth University12, Obihiro University of Agriculture and Veterinary Medicine13, Indian Institute of Technology Mandi14, Indian Institute of Science Education and Research, Bhopal15, Washington University in St. Louis16, International Centre of Insect Physiology and Ecology17, Egerton University18, New Mexico State University19, Institute of Tropical Medicine Antwerp20, University of Cincinnati21, International Atomic Energy Agency22, University of Patras23, Alexander Fleming Biomedical Sciences Research Center24, University of Illinois at Urbana–Champaign25, Wayne State University26, Rothamsted Research27, Jomo Kenyatta University of Agriculture and Technology28, National Institutes of Health29, Baylor University30, University of Wisconsin–Parkside31, Ohio State University32, University of Arizona33, Wellcome Trust34, University of Nairobi35, Slovak Academy of Sciences36, Howard Hughes Medical Institute37, University of Cape Town38, Katholieke Universiteit Leuven39, Virginia Tech40, Texas A&M University41, University of Pavia42, University of Pretoria43, University of Georgia44, North Carolina State University45, Kenyatta University46, West Virginia University47, St. Catharine College48, University of York49, California State Polytechnic University, Pomona50, Pasteur Institute51, Makerere University52, University of Notre Dame53, King Abdullah University of Science and Technology54, University of London55, French Alternative Energies and Atomic Energy Commission56, National Institute of Advanced Industrial Science and Technology57, Covenant University58, University of Tsukuba59
TL;DR: The sequence and annotation of the 366-megabase Glossina mors Titans morsitans genome are described, providing a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology.
Abstract: Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa.
Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission.
Notable differences between tsetse and other disease vectors include obligate microbial
symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation
of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the
12,308 predicted protein–encoding genes led to multiple discoveries, including chromosomal
integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins,
reduced complement of host pathogen recognition proteins, and reduced olfaction/chemosensory
associated genes. These genome data provide a foundation for research into trypanosomiasis
prevention and yield important insights with broad implications for multiple aspects of tsetse
biology.
242 citations
Authors
Showing all 1134 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Somnath Choudhury | 128 | 1264 | 80929 |
| Ashoke Sen | 108 | 517 | 40322 |
| Amit Kumar | 63 | 256 | 12509 |
| Manish Kumar | 61 | 1425 | 21762 |
| Pradeep K. Singh | 54 | 166 | 15002 |
| Kankan Bhattacharyya | 50 | 226 | 9752 |
| Pablo De Castro Manzano | 44 | 175 | 5704 |
| N. Mukunda | 43 | 205 | 6542 |
| Vinod K. Singh | 43 | 220 | 6404 |
| Sanjit Konar | 41 | 132 | 4721 |
| Nitin T. Patil | 41 | 162 | 5667 |
| Junho Kim | 39 | 110 | 3737 |
| Sampat K. Tandon | 36 | 105 | 3069 |
| Ayesha Begum | 33 | 83 | 4308 |
| Manish Kumar | 32 | 127 | 3815 |