Indian Institute of Technology Bombay

About: Indian Institute of Technology Bombay is a education organization based out in Mumbai, India. It is known for research contribution in the topics: Catalysis & Computer science. The organization has 16756 authors who have published 33588 publications receiving 570559 citations.

Health justice: An argument from the capabilities approach

Abstract: Health Justice is able to compile and create linkages between various notions of health that help us understand the problem of ill-health and to locate it within the framework of social justice. He...

Graphene oxide for electrochemical sensing applications

Abstract: By exploiting the presence of abundant carboxylic groups (–COOH) on graphene oxide (GO) and using EDC–NHS (1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride–N-hydroxysuccinimide) chemistry to covalently conjugate protein molecules, we demonstrate a novel electrochemical immunosensor for detection of antibody–antigen (Rabbit IgG–AntiRabbit IgG) interactions. The interactions were verified using Electrochemical Impedance Spectroscopy (EIS). Although GO is known to be a poor conductor, the charge transfer resistance (RP) of a GO modified glassy carbon electrode (GCE) was found to be as low as 1.26 Ω cm2. This value is similar to that obtained for reduced graphene oxide (RGO) or graphene and an order of magnitude less than bare GCE. The EIS monitored antibody–antigen interactions showed a linear increase in RP and the overall impedance of the system with increase of antibody concentration. Rabbit IgG antibodies were detected over a wide range of concentrations from 3.3 nM to 683 nM with the limit of detection (LOD) estimated to be 0.67 nM. The sensor showed high selectivity towards Rabbit IgG antibody as compared to non-complementary myoglobin. RGO modified GCE showed no sensing properties due to the removal of carboxylic groups which prevented subsequent chemical functionalization and immobilization of antigen molecules. The sensitivity and selectivity achievable by this simple label free technique hint at the possibility of GO becoming the electrode material of choice for future electrochemical sensing protocols.

The IIT Bombay English-Hindi Parallel Corpus.

Abstract: We present the IIT Bombay English-Hindi Parallel Corpus. The corpus is a compilation of parallel corpora previously available in the public domain as well as new parallel corpora we collected. The corpus contains 1.49 million parallel segments, of which 694k segments were not previously available in the public domain. The corpus has been pre-processed for machine translation, and we report baseline phrase-based SMT and NMT translation results on this corpus. This corpus has been used in two editions of shared tasks at the Workshop on Asian Language Translation (2016 and 2017). The corpus is freely available for non-commercial research. To the best of our knowledge, this is the largest publicly available English-Hindi parallel corpus.