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Institution

Indian Institute of Technology Indore

EducationIndore, Madhya Pradesh, India
About: Indian Institute of Technology Indore is a education organization based out in Indore, Madhya Pradesh, India. It is known for research contribution in the topics: Fading & Support vector machine. The organization has 1606 authors who have published 4803 publications receiving 66500 citations.


Papers
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Proceedings ArticleDOI
15 Apr 2018
TL;DR: A three-node wireless communications system, where two source nodes communicate to each other via a half-duplex battery-enabled relay node, and a hybrid decode-amplify-forward (HDAF) based relaying scheme is proposed to make the communication links more reliable.
Abstract: In this paper, we examine the performance of simultaneous wireless information and power transfer (SWIPT) in the two-way relay networks under Nakagami-m fading. We consider a three-node wireless communications system, where two source nodes communicate to each other via a half-duplex battery-enabled relay node. A hybrid decode-amplify-forward (HDAF) based relaying scheme is proposed to make the communication links more reliable. With this scheme, the relay node can harvest energy from the radio-frequency (RF) signals, and destination nodes can exploit the direct link. For harvesting energy from RF signals, we adopt time switching (TS) approach, whereby relay node first harvests energy from the received signals in the first phase (energy harvesting phase), and then utilizes the harvested energy to process and broadcast the received signals in next three consecutive (information processing) phases. At the destination nodes, selection combining (SC) technique is employed to make use of two intended signals received via direct and relay links. For this setup, we derive the closed-form expressions for user outage probability (OP) and achievable system throughput under Nakagami-m fading. Numerical and simulation results are provided to highlight the impact of various system and channel parameters on the SWIPT-enabled wireless system and to verify the accuracy of derived expressions.

36 citations

Journal ArticleDOI
TL;DR: It is reported for the first time, that HGQs in Nipah virus genome are targets for G-quadruplex specific ligands; therefore, could serve as potential targets for anti-viral therapy.
Abstract: The G-quadruplex (GQ) motifs are considered as potential drug-target sites for several human pathogenic viruses such as Zika, Hepatitis, Ebola, and Human Herpesviruses. The recent outbreaks of Nipah virus (NiV) in India, the highly fatal emerging zoonotic virus is a potential threat to global health security as no anti-viral drug or vaccine in currently available. Therefore, here in the present study, we sought to assess the ability of the putative G-quadruplex forming sequences in the NiV genome to form G-quadruplex structures and act as targets for anti-viral compounds. Bioinformatics analysis underpinned by various biophysical and biochemical techniques (such as NMR, CD, EMSA, DMS footprinting assay) confirmed the presence of two highly conserved G-quadruplex forming sequences (HGQs) in the G and L genes of NiV. These genes encode the cell attachment glycoprotein and RNA-dependent RNA polymerase, respectively and are essential for the virus entry and replication within the host cell. It remains possible that stabilization of these HGQs by the known G-quadruplex binding ligands like TMPyP4 and Braco-19 represents a promising strategy to inhibit the expression of the HGQ harboring genes and thereby stop the viral entry and replication inside the host cell. Accordingly, we report for the first time, that HGQs in Nipah virus genome are targets for G-quadruplex specific ligands; therefore, could serve as potential targets for anti-viral therapy.

36 citations

Journal ArticleDOI
TL;DR: In this article, a review article covers the recent developments in direct C-H functionalization of quinoxalin-2(1H)-one derivatives via radical additions at the C3 position.
Abstract: This review article covers the recent developments in direct C–H functionalization of quinoxalin-2(1H)-one derivatives via radical additions at the C3 position. Reaction types have been categorized depending on the kind of radical used, with representative examples and insightful mechanistic details provided. 1 Introduction 2 Reactions with Alkyl Radicals 3 Reactions with Acyl Radicals 4 Reactions with Aryl Radicals 5 Reactions with Perfluoroalkyl Radicals 6 Reactions with Alkoxycarbonyl Radicals 7 Reactions with Nitrogen Radicals 8 Reactions with Oxygen Radicals 9 Reactions with Phosphorus Radicals 10 Conclusion

36 citations

Journal ArticleDOI
TL;DR: In this paper, the authors proposed two DC-DC converters, namely semi-tapped and fully tapped quadratic boost converter, for high step-up applications such as micro-inverter.

36 citations

Journal ArticleDOI
25 Jan 2020-Langmuir
TL;DR: The formation of G-quadruplex hydrogel via the multi-component self-assembly and reversible bond formation between guanosine (G) and 1-naphthaleneboronic acid (NapBA) in presence of monovalent cation K+.
Abstract: Injectable, self-healable, and biocompatible dynamic hydrogels prepared from the molecular self-assembly and reversible covalent bond formation of low-molecular-weight hydrogelators are increasing in the field of drug delivery. Herein, we report the formation of G-quadruplex hydrogels via the multicomponent self-assembly and reversible bond formation between guanosine (G) and 1-naphthaleneboronic acid in the presence of the monovalent cation K+. The cation-templated stacking interaction of G4 quartets and the formation of dynamic cyclic boronate esters are responsible for the construction of dynamic G-quadruplex assembly. The in situ-synthesized dynamic cyclic boronate esters are well characterized by 11B nuclear magnetic resonance and Fourier transform infrared spectroscopy methods. The formation and morphology of the G-quadruplex hydrogel are well supported by several spectroscopic and microscopic techniques. The injectability and self-healing ability of the G-quadruplex hydrogel are also investigated. The in vivo cytotoxicity of the G-quadruplex hydrogel is extensively evaluated over different cell lines (HeLa, MCF-7, and HEK293) to observe the biostability and broad-spectrum biocompatibility of the hydrogel. Further, this injectable, biocompatible G-quadruplex hydrogel has been used for encapsulation and sustained release of two important vitamins (B2 and B12) over 40 h at physiological pH (7.46) and temperature (37 °C) without the influence of any external stimuli.

36 citations


Authors

Showing all 1738 results

NameH-indexPapersCitations
Raghunath Sahoo10655637588
Biswajeet Pradhan9873532900
A. Kumar9650533973
Franco Meddi8447624084
Manish Sharma82140733361
Anindya Roy5930114306
Krishna R. Reddy5840011076
Sudipan De549910774
Sudip Chakraborty513439319
Shaikh M. Mobin5151511467
Ashok Kumar5040510001
Ankhi Roy492598634
Aditya Nath Mishra491397607
Ram Bilas Pachori481828140
Pragati Sahoo471336535
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202365
2022253
2021914
2020801
2019677
2018614