Indian Institute of Technology Indore

About: Indian Institute of Technology Indore is a education organization based out in Indore, Madhya Pradesh, India. It is known for research contribution in the topics: Fading & Support vector machine. The organization has 1606 authors who have published 4803 publications receiving 66500 citations.

Applicability of Transconductance-to-Current Ratio ( $g_{\mathrm {m}}/I_{\mathrm {ds}}$ ) as a Sensing Metric for Tunnel FET Biosensors

Abstract: In this paper, we propose and evaluate the feasibility of transconductance-to-current ratio ( $g_{\mathrm {{m}}}/I_{\mathrm {{ds}}}$ ) as a sensing metric for a tunnel field-effect transistor (TFET)-based dielectric modulated biosensor. Focusing on the enhancement of the values of $g_{\mathrm {{m}}}/I_{\mathrm {{ds}}}$ and current ratio at lower current levels to signify the presence of biomolecules in the dielectric cavity of TFET biosensor, the metric can be used not only for sensitivity but also for selectivity as the current ratio changes appreciably for the three different types of biomolecules, namely, Streptavidin, Biotin, and APTES. The $g_{\mathrm {{m}}}/I_{\mathrm {{ds}}}$ extraction takes into account the operation at low power consumption, i.e., in the subthreshold region, which is most sensitive for biomolecule detection. The sensing methodology is governed by the location of the biomolecules within the cavity, and is less dependent on the fill-in factor. This paper highlights new opportunities to identify the sensing metric in TFET-based dielectric modulated biosensors.

Impacts of G2V and V2G power on electricity demand profile

Abstract: Successful integration of growing number of energy-efficient electric vehicles (EV) into existing power grid necessitates the study of impacts posed by their adoption in larger numbers. However, their gradual adoption will give sufficient time to the utilities for planning the infrastructure upgrades to prevent destabilization of power network. The work presented in this paper investigates the proportion of energy that can be injected back into the grid by EVs through vehicle-to-grid (V2G) mechanism. The V2G energy profiles are obtained using constant power discharging approach for various power levels (as per charging standards) during the time vehicles are parked. For charging, constant power followed by constant time charging approach is used in succession complying with Li-ion battery charging characteristics together with a constraint of retaining reasonable battery lifetime. The simultaneous effect of V2G power and resulting G2V load on typical daily load curve is figured taking modified IEEE 30-bus as a test system.

Phenolate based metallomacrocyclic xanthate complexes of CoII/CuII and their exclusive deployment in [2 : 2] binuclear N,O-Schiff base macrocycle formation and in vitro anticancer studies

Abstract: Potassium salts of phenolate based polydentate xanthate ligands 4,4′-bis(2-dithiocarbonatobenzylideneamino)diphenyl ether (K2xan1) and 4,4′-bis(2-dithiocarbonatonaphthylmethylideneamino)diphenyl ether (K2xan2) have been synthesized and characterized, prior to use. The reaction of K2xan1 or K2xan2 with M(OAc)2 in Et3N affords access to a rare series of binuclear metallomacrocyclic xanthate complexes of the type [M2-μ2-bis-(κ2S,S-xan1/xan2)] (1–4) which quickly forms [2 : 2] binuclear N,O-bidentate Schiff base macrocyclic complexes of the type [M2-μ2-bis-(κ2N,O-L1/L2)] (L1 = 4,4′-bis(2-hydroxybenzylideneamino)diphenyl ether, L2 = 4,4′-bis(2-hydroxynaphthylmethylidene-amino)diphenyl ether) 5–8via evolution of CS2 in solution. The compounds were characterized by microanalysis, relevant spectroscopy (FT-IR, UV-visible), mass spectrometry (ESI-MS), and powder and single crystal XRD techniques. In vitro anticancer activity of all the compounds was evaluated against HEP 3B (hepatoma) and IMR 32 (neuroblastoma) by the MTT assay. Remarkably, the binuclear copper(II) xanthate complexes were found to be extremely active against both the cell lines (IC50: 8.1 ± 0.8 μM (3), 8.8 ± 1.7 μM (4) against HEP 3B and 1.9 ± 0.3 μM (3) and 7.3 ± 0.6 μM (4) against IMR 32) and this projects them as good candidates for potent antitumor agents and the IC50 values confirm their better potency than the reference drug cisplatin. The flow-cytometric density plot illustrates the induction of apoptosis in HEP 3B and IMR 32 cells after treatment with K2xan1, 1, 3, 6 and 7.

Doping-Induced Combined Fano and Phonon Confinement Effect in La-Doped CeO2: Raman Spectroscopy Analysis

Abstract: The effect of La-doping on the crystallographic structure and the Raman line-shape of CeO2 has been investigated. X-ray diffraction analysis suggests that the lattice parameter and the Ce/La–O bond...