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Institution

Indian Institute of Technology Kharagpur

EducationKharagpur, India
About: Indian Institute of Technology Kharagpur is a education organization based out in Kharagpur, India. It is known for research contribution in the topics: Natural rubber & Dielectric. The organization has 16887 authors who have published 38658 publications receiving 714526 citations.


Papers
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Journal ArticleDOI
TL;DR: In this article, an experimental investigation of fault diagnosis in a multistage gearbox under transient loads was carried out, where an induction motor drives the multi-stage gearbox, which is connected to a DC generator for loading purpose.

138 citations

Journal ArticleDOI
TL;DR: The current status of exosome as a delivery vehicle for therapeutics and the challenges that need to be overcome are covered, and the future perspectives of this exciting field of research are discussed to transform it from bench to clinical reality.
Abstract: The effective delivery of target-specific siRNA to the brain by exploiting the exosomes derived from dendritic cells renders the paradigm shift for the prospective use of nanosized exosomes as a delivery system. Although the in vivo targeting strategies by other nanovesicles like liposomes exist, still this novel exosome-based delivery approach holds an inclusive dominance of in vivo security and reduced immunogenicity. Achieving promising exosome-based delivery strategies warrants more desirable exploration of their biology. Over the years, the invention of novel production, characterization, targeting strategies, and cargo loading techniques of exosome improved its ability to reach clinics. Essentially, exosome-based delivery of therapeutics assures to conquer the major hurdles, like delivery of cargos across impermeable biological barriers, like the blood-brain barrier, biocompatibility, increased solubility, metabolic stability, improved circulation time, target specific delivery, and pharmacokinetics, and thereby enhanced the efficacy of loaded therapeutic agents. In this article, we cover the current status of exosome as a delivery vehicle for therapeutics and the challenges that need to be overcome, and we also discuss future perspectives of this exciting field of research to transform it from bench to clinical reality.

138 citations

Journal ArticleDOI
TL;DR: The average activity concentrations of radioactive elements such as 232 Th, 238 U and 40 K, measured by gamma-ray spectrometry using an HPGe detector, and found to be 2825±50, 350±20 and 180±25 Bq kg −1, respectively, for the bulk sand samples as discussed by the authors.

137 citations

Journal ArticleDOI
TL;DR: Fabricated n-MoS2/p-Si 0D/3D heterojunctions exhibiting excellent rectification behavior have been studied for light emission in the forward bias and photodetection in the reverse bias and are found to be superior to the reported results on large areaPhotodetector devices fabricated using two dimensional materials.
Abstract: Silicon compatible wafer scale MoS2 heterojunctions are reported for the first time using colloidal quantum dots. Size dependent direct band gap emission of MoS2 dots are presented at room temperature. The temporal stability and decay dynamics of excited charge carriers in MoS2 quantum dots have been studied using time correlated single photon counting spectroscopy technique. Fabricated n-MoS2/p-Si 0D/3D heterojunctions exhibiting excellent rectification behavior have been studied for light emission in the forward bias and photodetection in the reverse bias. The electroluminescences with white light emission spectra in the range of 450–800 nm are found to be stable in the temperature range of 10–350 K. Size dependent spectral responsivity and detectivity of the heterojunction devices have been studied. The peak responsivity and detectivity of the fabricated heterojunction detector are estimated to be ~0.85 A/W and ~8 × 1011 Jones, respectively at an applied bias of −2 V for MoS2 QDs of 2 nm mean diameter. The above values are found to be superior to the reported results on large area photodetector devices fabricated using two dimensional materials.

137 citations

Journal ArticleDOI
TL;DR: To study the intra- and intermolecular reactivities another related descriptor, namely, the nucleophilicity excess (Deltaomega(g)-/+) for a nucleophile over the electrophilicity in it, has been defined and tested on all-metal aromatic compounds.
Abstract: In line with the local philicity concept proposed by Chattaraj et al. (Chattaraj, P. K.; Maiti, B.; Sarkar, U. J. Phys. Chem. A. 2003, 107, 4973) and a dual descriptor derived by Morell, Grand and Toro-Labbe, (J. Phys. Chem. A 2005, 109, 205), we propose a multiphilic descriptor. It is defined as the difference between nucleophilic (omega(k)+) and electrophilic (omega(k)-) condensed philicity functions. This descriptor is capable of simultaneously explaining the nucleophilicity and electrophilicity of the given atomic sites in the molecule. Variation of these quantities along the path of a soft reaction is also analyzed. Predictive ability of this descriptor has been successfully tested on the selected systems and reactions. Corresponding force profiles are also analyzed in some representative cases. Also, to study the intra- and intermolecular reactivities another related descriptor, namely, the nucleophilicity excess (Deltaomega(g)-/+) for a nucleophile over the electrophilicity in it, has been defined and tested on all-metal aromatic compounds.

137 citations


Authors

Showing all 17290 results

NameH-indexPapersCitations
Rajdeep Mohan Chatterjee11099051407
Vijay P. Singh106169955831
Arun Majumdar10245952464
Sanjay Gupta9990235039
Biswajeet Pradhan9873532900
Sandeep Kumar94156338652
Jürgen Eckert92136842119
Praveen Kumar88133935718
Tuan Vo-Dinh8669824690
Lawrence Carin8494931928
Anindya Dutta8224833619
Aniruddha B. Pandit8042722552
Krishnendu Chakrabarty7999627583
Ramesh Jain7855637037
Thomas Thundat7862222684
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023284
2022849
20213,142
20202,907
20192,779
20182,489