Indiana University

About: Indiana University is a education organization based out in Bloomington, Indiana, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 64480 authors who have published 150058 publications receiving 6392902 citations. The organization is also known as: Indiana University system & indiana.edu.

A New Look at Dissonance Theory

Abstract: Publisher Summary Cognitive dissonance occurs when a cognition that a person holds follows from the obverse of another. This chapter examines those relationships and proposes a new definition of cognitive dissonance. The state of the empirical findings to move toward a more comprehensive view of dissonance is reviewed in the chapter. When one understands what produces dissonance, it still needs further elaboration of the process to understand adequately the cognitive changes that ensue. The concept of dissonance must be differentiated into the concepts of dissonance arousal and dissonance motivation. It leads to the cognitive changes that are generally associated with cognitive dissonance. The integrative review of dissonance research is provided in the chapter. This survey narrows the scope of the theory, because it identifies the limited conditions under which dissonance effects are most likely to arise; cognitive dissonance is not the product of opposing cognitions. Dissonance theory concepts are applied to a broad range of phenomena so that the formulation remains exceedingly important.

Organizational dissidence: The case of whistle-blowing

Abstract: Research on whistle-blowing has been hampered by a lack of a sound theoretical base. In this paper, we draw upon existing theories of motivation and power relationships to propose a model of the whistle-blowing process. This model focuses on decisions made by organization members who believe they have evidence of organizational wrongdoing, and the reactions of organization authorities. Based on a review of the sparse empirical literature, we suggest variables that may affect both the members' decisions and the organization's responses.

Negative plant–soil feedback predicts tree-species relative abundance in a tropical forest

Abstract: One potential mechanism for maintaining biodiversity is negative feedback between a species and its specific enemies, allowing rival species to thrive in the vicinity in preference to individuals of the species in question. The effect of soil biota has often been overlooked in the past, with more attention being paid to factors such as above-ground herbivory and resource partitioning. But a series of shade-house and field experiments now shows that in a tropical forest, it is the soil biota that is the main cause of this feedback, and that this effect is sufficient to explain the diversity. One potential mechanism for maintaining biodiversity is negative feedback between a species and its specific enemies, meaning that other species can grow in its vicinity better than further individuals of the species in question. These authors show that in a tropical forest it is the soil biota that is the main cause of this feedback, and that this effect can explain the diversity. The accumulation of species-specific enemies around adults is hypothesized to maintain plant diversity by limiting the recruitment of conspecific seedlings relative to heterospecific seedlings1,2,3,4,5,6. Although previous studies in forested ecosystems have documented patterns consistent with the process of negative feedback7,8,9,10,11,12,13,14,15,16, these studies are unable to address which classes of enemies (for example, pathogens, invertebrates, mammals) exhibit species-specific effects strong enough to generate negative feedback17, and whether negative feedback at the level of the individual tree is sufficient to influence community-wide forest composition. Here we use fully reciprocal shade-house and field experiments to test whether the performance of conspecific tree seedlings (relative to heterospecific seedlings) is reduced when grown in the presence of enemies associated with adult trees. Both experiments provide strong evidence for negative plant–soil feedback mediated by soil biota. In contrast, above-ground enemies (mammals, foliar herbivores and foliar pathogens) contributed little to negative feedback observed in the field. In both experiments, we found that tree species that showed stronger negative feedback were less common as adults in the forest community, indicating that susceptibility to soil biota may determine species relative abundance in these tropical forests. Finally, our simulation models confirm that the strength of local negative feedback that we measured is sufficient to produce the observed community-wide patterns in tree-species relative abundance. Our findings indicate that plant–soil feedback is an important mechanism that can maintain species diversity and explain patterns of tree-species relative abundance in tropical forests.

Bridging the gap: a genre analysis of Weblogs

Abstract: Weblogs (blogs) - frequently modified Web pages in which dated entries are listed in reverse chronological sequence - are the latest genre of Internet communication to attain widespread popularity, yet their characteristics have not been systematically described. This paper presents the results of a content analysis of 203 randomly-selected Weblogs, comparing the empirically observable features of the corpus with popular claims about the nature of Weblogs, and finding them to differ in a number of respects. Notably, blog authors, journalists and scholars alike exaggerate the extent to which blogs are interlinked, interactive, and oriented towards external events, and underestimate the importance of blogs as individualistic, intimate forms of self-expression. Based on the profile generated by the empirical analysis, we consider the likely antecedents of the blog genre, situate it with respect to the dominant forms of digital communication on the Internet today, and advance predictions about its long-term impacts.

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

Abstract: BackgroundThe immunopathogenesis of type 1 diabetes mellitus is associated with T-lymphocyte autoimmunity. However, there is growing evidence that B lymphocytes play a role in many T-lymphocyte–mediated diseases. It is possible to achieve selective depletion of B lymphocytes with rituximab, an anti-CD20 monoclonal antibody. This phase 2 study evaluated the role of B-lymphocyte depletion in patients with type 1 diabetes. MethodsWe conducted a randomized, double-blind study in which 87 patients between 8 and 40 years of age who had newly diagnosed type 1 diabetes were assigned to receive infusions of rituximab or placebo on days 1, 8, 15, and 22 of the study. The primary outcome, assessed 1 year after the first infusion, was the geometric mean area under the curve (AUC) for the serum C-peptide level during the first 2 hours of a mixed-meal tolerance test. Secondary outcomes included safety and changes in the glycated hemoglobin level and insulin dose. ResultsAt 1 year, the mean AUC for the level of C peptid...