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Showing papers by "Instituto Politécnico Nacional published in 2014"


Journal ArticleDOI
Heike Rauer1, Heike Rauer2, C. Catala3, Conny Aerts4  +164 moreInstitutions (51)
TL;DR: The PLATO 2.0 mission as discussed by the authors has been selected for ESA's M3 launch opportunity (2022/24) to provide accurate key planet parameters (radius, mass, density and age) in statistical numbers.
Abstract: PLATO 2.0 has recently been selected for ESA’s M3 launch opportunity (2022/24). Providing accurate key planet parameters (radius, mass, density and age) in statistical numbers, it addresses fundamental questions such as: How do planetary systems form and evolve? Are there other systems with planets like ours, including potentially habitable planets? The PLATO 2.0 instrument consists of 34 small aperture telescopes (32 with 25 s readout cadence and 2 with 2.5 s candence) providing a wide field-of-view (2232 deg 2) and a large photometric magnitude range (4–16 mag). It focusses on bright (4–11 mag) stars in wide fields to detect and characterize planets down to Earth-size by photometric transits, whose masses can then be determined by ground-based radial-velocity follow-up measurements. Asteroseismology will be performed for these bright stars to obtain highly accurate stellar parameters, including masses and ages. The combination of bright targets and asteroseismology results in high accuracy for the bulk planet parameters: 2 %, 4–10 % and 10 % for planet radii, masses and ages, respectively. The planned baseline observing strategy includes two long pointings (2–3 years) to detect and bulk characterize planets reaching into the habitable zone (HZ) of solar-like stars and an additional step-and-stare phase to cover in total about 50 % of the sky. PLATO 2.0 will observe up to 1,000,000 stars and detect and characterize hundreds of small planets, and thousands of planets in the Neptune to gas giant regime out to the HZ. It will therefore provide the first large-scale catalogue of bulk characterized planets with accurate radii, masses, mean densities and ages. This catalogue will include terrestrial planets at intermediate orbital distances, where surface temperatures are moderate. Coverage of this parameter range with statistical numbers of bulk characterized planets is unique to PLATO 2.0. The PLATO 2.0 catalogue allows us to e.g.: - complete our knowledge of planet diversity for low-mass objects, - correlate the planet mean density-orbital distance distribution with predictions from planet formation theories,- constrain the influence of planet migration and scattering on the architecture of multiple systems, and - specify how planet and system parameters change with host star characteristics, such as type, metallicity and age. The catalogue will allow us to study planets and planetary systems at different evolutionary phases. It will further provide a census for small, low-mass planets. This will serve to identify objects which retained their primordial hydrogen atmosphere and in general the typical characteristics of planets in such low-mass, low-density range. Planets detected by PLATO 2.0 will orbit bright stars and many of them will be targets for future atmosphere spectroscopy exploring their atmosphere. Furthermore, the mission has the potential to detect exomoons, planetary rings, binary and Trojan planets. The planetary science possible with PLATO 2.0 is complemented by its impact on stellar and galactic science via asteroseismology as well as light curves of all kinds of variable stars, together with observations of stellar clusters of different ages. This will allow us to improve stellar models and study stellar activity. A large number of well-known ages from red giant stars will probe the structure and evolution of our Galaxy. Asteroseismic ages of bright stars for different phases of stellar evolution allow calibrating stellar age-rotation relationships. Together with the results of ESA’s Gaia mission, the results of PLATO 2.0 will provide a huge legacy to planetary, stellar and galactic science.

965 citations


Journal ArticleDOI
S. Chatrchyan, Khachatryan1, Albert M. Sirunyan, Armen Tumasyan  +2384 moreInstitutions (207)
26 May 2014
TL;DR: In this paper, a description of the software algorithms developed for the CMS tracker both for reconstructing charged-particle trajectories in proton-proton interactions and for using the resulting tracks to estimate the positions of the LHC luminous region and individual primary-interaction vertices is provided.
Abstract: A description is provided of the software algorithms developed for the CMS tracker both for reconstructing charged-particle trajectories in proton-proton interactions and for using the resulting tracks to estimate the positions of the LHC luminous region and individual primary-interaction vertices. Despite the very hostile environment at the LHC, the performance obtained with these algorithms is found to be excellent. For tt events under typical 2011 pileup conditions, the average track-reconstruction efficiency for promptly-produced charged particles with transverse momenta of p_T > 0.9GeV is 94% for pseudorapidities of |η| < 0.9 and 85% for 0.9 < |η| < 2.5. The inefficiency is caused mainly by hadrons that undergo nuclear interactions in the tracker material. For isolated muons, the corresponding efficiencies are essentially 100%. For isolated muons of p_T = 100GeV emitted at |η| < 1.4, the resolutions are approximately 2.8% in p_T, and respectively, 10μm and 30μm in the transverse and longitudinal impact parameters. The position resolution achieved for reconstructed primary vertices that correspond to interesting pp collisions is 10–12μm in each of the three spatial dimensions. The tracking and vertexing software is fast and flexible, and easily adaptable to other functions, such as fast tracking for the trigger, or dedicated tracking for electrons that takes into account bremsstrahlung.

559 citations


Journal ArticleDOI
K. Abe1, J. Adam2, Hiroaki Aihara3, T. Akiri4  +335 moreInstitutions (52)
TL;DR: The T2K experiment has observed electron neutrino appearance in a muon neutrinos beam produced 295 km from the Super-Kamiokande detector with a peak energy of 0.6 GeV, corresponding to a significance of 7.3σ.
Abstract: The T2K experiment has observed electron neutrino appearance in a muon neutrino beam produced 295 km from the Super-Kamiokande detector with a peak energy of 0.6 GeV. A total of 28 electron neutrino events were detected with an energy distribution consistent with an appearance signal, corresponding to a significance of 7.3 sigma when compared to 4.92 +/- 0.55 expected background events. In the Pontecorvo-Maki-Nakagawa-Sakata mixing model, the electron neutrino appearance signal depends on several parameters including three mixing angles theta(12), theta(23), theta(13), a mass difference vertical bar Delta m(32)(2)vertical bar and a CP violating phase delta(CP). In this neutrino oscillation scenario, assuming vertical bar Delta m(32)(2)vertical bar = 2.4 x 10(-3) eV(2), sin theta(2)(23) = 0.5, and vertical bar Delta m(32)(2)vertical bar > 0 (vertical bar Delta m(32)(2)vertical bar <0), a best- fit value of sin2 theta(2)(13) = 0.140(- 0.032)(+0.038) (0.170(-0.037)(+0.045)) is obtained at delta(CP) = 0. When combining the result with the current best knowledge of oscillation parameters including the world average value of theta(13) from reactor experiments, some values of delta(CP) are disfavored at the 90% C. L.

515 citations


Journal ArticleDOI
M. Bicer1, H. Duran Yildiz1, I. Yildiz2, G. Coignet3, Marco Delmastro3, Theodoros Alexopoulos4, Christophe Grojean, Stefan Antusch5, Tanaji Sen6, Hong-Jian He7, K. Potamianos8, Sigve Haug9, Asunción Moreno, Arno Heister10, Veronica Sanz11, Guillelmo Gomez-Ceballos12, Markus Klute12, Marco Zanetti12, Lian-Tao Wang13, Mogens Dam14, Celine Boehm15, Nigel Glover15, Frank Krauss15, Alexander Lenz15, Michael Syphers16, Christos Leonidopoulos17, Vitaliano Ciulli, P. Lenzi, Giacomo Sguazzoni, Massimo Antonelli, Manuela Boscolo, Umberto Dosselli, O. Frasciello, C. Milardi, G. Venanzoni, Mikhail Zobov, J.J. van der Bij18, M. De Gruttola19, D. W. Kim20, Michail Bachtis21, A. Butterworth21, C. Bernet21, Cristina Botta21, Federico Carminati21, A. David21, L. Deniau21, David D'Enterria21, Gerardo Ganis21, Brennan Goddard21, Gian F. Giudice21, Patrick Janot21, John Jowett21, Carlos Lourenco21, L. Malgeri21, Emilio Meschi21, Filip Moortgat21, Pasquale Musella21, J. A. Osborne21, Luca Perrozzi21, Maurizio Pierini21, Louis Rinolfi21, A. De Roeck21, Juan Rojo21, G. Roy21, Andrea Sciabà21, A. Valassi21, C. S. Waaijer21, Jorg Wenninger21, H. K. Woehri21, Frank Zimmermann21, A. Blondel22, Michael Koratzinos22, Philippe Mermod22, Yasar Onel23, R. Talman24, E. Castaneda Miranda25, Eugene Bulyak, D. Porsuk, Dmytro Kovalskyi26, Sanjay Padhi26, Pietro Faccioli, John Ellis27, Mario Campanelli28, Yang Bai29, M. Chamizo, Robert Appleby30, Hywel Owen30, H. Maury Cuna31, C. Gracios32, German Ardul Munoz-Hernandez32, Luca Trentadue33, E. Torrente-Lujan34, S. Wang35, David Bertsche36, A. V. Gramolin37, Valery I. Telnov37, Marumi Kado38, P. Petroff38, Patrizia Azzi, Oreste Nicrosini, Fulvio Piccinini, Guido Montagna39, F. Kapusta38, S. Laplace38, W. Da Silva38, Nectaria A. B. Gizani40, Nathaniel Craig41, Tao Han42, Claudio Luci43, Barbara Mele43, Luca Silvestrini43, Marco Ciuchini, R. Cakir44, R. Aleksan, Fabrice Couderc, Serguei Ganjour, Eric Lancon, Elizabeth Locci, P. Schwemling, M. Spiro, C. Tanguy, Jean Zinn-Justin, Stefano Moretti45, M. Kikuchi46, Haruyo Koiso46, Kazuhito Ohmi46, Katsunobu Oide46, G. Pauletta47, Roberto Ruiz de Austri48, Maxime Gouzevitch38, Subhasis Chattopadhyay49 
TL;DR: In this article, the authors present a first appraisal of the salient features of the TLEP physics potential, to serve as a baseline for a more extensive design study, and present a combination of TLEp and the VHE-LHC offers, for a great cost effectiveness, the best precision and the best search reach of all options presently on the market.
Abstract: The discovery by the ATLAS and CMS experiments of a new boson with mass around 125 GeV and with measured properties compatible with those of a Standard-Model Higgs boson, coupled with the absence of discoveries of phenomena beyond the Standard Model at the TeV scale, has triggered interest in ideas for future Higgs factories. A new circular e+e- collider hosted in a 80 to 100 km tunnel, TLEP, is among the most attractive solutions proposed so far. It has a clean experimental environment, produces high luminosity for top-quark, Higgs boson, W and Z studies, accommodates multiple detectors, and can reach energies up to the t-tbar threshold and beyond. It will enable measurements of the Higgs boson properties and of Electroweak Symmetry-Breaking (EWSB) parameters with unequalled precision, offering exploration of physics beyond the Standard Model in the multi-TeV range. Moreover, being the natural precursor of the VHE-LHC, a 100 TeV hadron machine in the same tunnel, it builds up a long-term vision for particle physics. Altogether, the combination of TLEP and the VHE-LHC offers, for a great cost effectiveness, the best precision and the best search reach of all options presently on the market. This paper presents a first appraisal of the salient features of the TLEP physics potential, to serve as a baseline for a more extensive design study.

445 citations


Journal ArticleDOI
TL;DR: This review pursues a twofold goal, to preserve and enhance the chronicles of recent educational data mining (EDM) advances development, and provides an analysis of the EDM strengths, weakness, opportunities, and threats, whose factors represent, in a sense, future work to be fulfilled.
Abstract: This review pursues a twofold goal, the first is to preserve and enhance the chronicles of recent educational data mining (EDM) advances development; the second is to organize, analyze, and discuss the content of the review based on the outcomes produced by a data mining (DM) approach. Thus, as result of the selection and analysis of 240 EDM works, an EDM work profile was compiled to describe 222 EDM approaches and 18 tools. A profile of the EDM works was organized as a raw data base, which was transformed into an ad-hoc data base suitable to be mined. As result of the execution of statistical and clustering processes, a set of educational functionalities was found, a realistic pattern of EDM approaches was discovered, and two patterns of value-instances to depict EDM approaches based on descriptive and predictive models were identified. One key finding is: most of the EDM approaches are ground on a basic set composed by three kinds of educational systems, disciplines, tasks, methods, and algorithms each. The review concludes with a snapshot of the surveyed EDM works, and provides an analysis of the EDM strengths, weakness, opportunities, and threats, whose factors represent, in a sense, future work to be fulfilled.

414 citations


Journal ArticleDOI
TL;DR: This study shows that, even in high-diversity systems, such as tropical reefs, functional diversity remains highly vulnerable to species loss.
Abstract: When tropical systems lose species, they are often assumed to be buffered against declines in functional diversity by the ability of the species-rich biota to display high functional redundancy: i.e., a high number of species performing similar functions. We tested this hypothesis using a ninefold richness gradient in global fish faunas on tropical reefs encompassing 6,316 species distributed among 646 functional entities (FEs): i.e., unique combinations of functional traits. We found that the highest functional redundancy is located in the Central Indo-Pacific with a mean of 7.9 species per FE. However, this overall level of redundancy is disproportionately packed into few FEs, a pattern termed functional over-redundancy (FOR). For instance, the most speciose FE in the Central Indo-Pacific contains 222 species (out of 3,689) whereas 38% of FEs (180 out of 468) have no functional insurance with only one species. Surprisingly, the level of FOR is consistent across the six fish faunas, meaning that, whatever the richness, over a third of the species may still be in overrepresented FEs whereas more than one third of the FEs are left without insurance, these levels all being significantly higher than expected by chance. Thus, our study shows that, even in high-diversity systems, such as tropical reefs, functional diversity remains highly vulnerable to species loss. Although further investigations are needed to specifically address the influence of redundant vs. vulnerable FEs on ecosystem functioning, our results suggest that the promised benefits from tropical biodiversity may not be as strong as previously thought.

371 citations


Journal ArticleDOI
TL;DR: The CCL2-CCR2 axis regulates macrophage polarization by influencing the expression of functionally relevant and polarization-associated genes and downmodulating proinflammatory cytokine production.
Abstract: The CCL2 chemokine mediates monocyte egress from bone marrow and recruitment into inflamed tissues through interaction with the CCR2 chemokine receptor, and its expression is upregulated by proinflammatory cytokines. Analysis of the gene expression profile in GM-CSF- and M-CSF-polarized macrophages revealed that a high CCL2 expression characterizes macrophages generated under the influence of M-CSF, whereas CCR2 is expressed only by GM-CSF-polarized macrophages. Analysis of the factors responsible for this differential expression identified activin A as a critical factor controlling the expression of the CCL2/CCR2 pair in macrophages, as activin A increased CCR2 expression but inhibited the acquisition of CCL2 expression by M-CSF-polarized macrophages. CCL2 and CCR2 were found to determine the extent of macrophage polarization because CCL2 enhances the LPS-induced production of IL-10, whereas CCL2 blockade leads to enhanced expression of M1 polarization-associated genes and cytokines, and diminished expression of M2-associated markers in human macrophages. Along the same line, Ccr2-deficient bone marrow-derived murine macrophages displayed an M1-skewed polarization profile at the transcriptomic level and exhibited a significantly higher expression of proinflammatory cytokines (TNF-α, IL-6) in response to LPS. Therefore, the CCL2-CCR2 axis regulates macrophage polarization by influencing the expression of functionally relevant and polarization-associated genes and downmodulating proinflammatory cytokine production.

345 citations


Journal ArticleDOI
S. Chatrchyan1, Vardan Khachatryan1, Albert M. Sirunyan1, Armen Tumasyan1  +2280 moreInstitutions (177)
TL;DR: In this paper, a search for a standard model Higgs boson decaying into a pair of tau leptons is performed using events recorded by the CMS experiment at the LHC in 2011 and 2012.
Abstract: A search for a standard model Higgs boson decaying into a pair of tau leptons is performed using events recorded by the CMS experiment at the LHC in 2011 and 2012. The dataset corresponds to an integrated luminosity of 4.9 inverse femtobarns at a centre-of-mass energy of 7 TeV and 19.7 inverse femtobarns at 8 TeV. Each tau lepton decays hadronically or leptonically to an electron or a muon, leading to six different final states for the tau-lepton pair, all considered in this analysis. An excess of events is observed over the expected background contributions, with a local significance larger than 3 standard deviations for m[H] values between 115 and 130 GeV. The best fit of the observed H to tau tau signal cross section for m[H] = 125 GeV is 0.78 +- 0.27 times the standard model expectation. These observations constitute evidence for the 125 GeV Higgs boson decaying to a pair of tau leptons.

345 citations


Journal ArticleDOI
TL;DR: This review will focus on the molecular mechanism by which ROS/RNS generation, redox signaling, and/or oxidative stress/damage alter autophagic flux rates, and the role of autophagy as a cell death process or survival mechanism in response to oxidative stress.
Abstract: Significance: The molecular machinery regulating autophagy has started becoming elucidated, and a number of studies have undertaken the task to determine the role of autophagy in cell fate determination within the context of human disease progression Oxidative stress and redox signaling are also largely involved in the etiology of human diseases, where both survival and cell death signaling cascades have been reported to be modulated by reactive oxygen species (ROS) and reactive nitrogen species (RNS) Recent Advances: To date, there is a good understanding of the signaling events regulating autophagy, as well as the signaling processes by which alterations in redox homeostasis are transduced to the activation/regulation of signaling cascades However, very little is known about the molecular events linking them to the regulation of autophagy This lack of information has hampered the understanding of the role of oxidative stress and autophagy in human disease progression Critical Issues: In th

321 citations


Journal ArticleDOI
Markus Ackermann, Andrea Albert1, W. B. Atwood2, Luca Baldini3  +159 moreInstitutions (39)
TL;DR: In this article, the authors analyzed 50 months of Fermi Large Area Telescope (LAT) data between 100 MeV and 500 GeV above 10 deg in Galactic latitude to derive the spectrum and morphology of two large structures in the gamma-ray sky extending to 55 deg below the Galactic center.
Abstract: The Fermi bubbles are two large structures in the gamma-ray sky extending to 55 deg above and below the Galactic center. We analyze 50 months of Fermi Large Area Telescope data between 100 MeV and 500 GeV above 10 deg in Galactic latitude to derive the spectrum and morphology of the Fermi bubbles. We thoroughly explore the systematic uncertainties that arise when modeling the Galactic diffuse emission through two separate approaches. The gamma-ray spectrum is well described by either a log parabola or a power law with an exponential cutoff. We exclude a simple power law with more than 7 sigma significance. The power law with an exponential cutoff has an index of 1.90+/-0.2 and a cutoff energy of 110+/- 50 GeV. We find that the gamma-ray luminosity of the bubbles is 4.4(+)2.4(-0.9 ) 10(exp 37) erg s-1. We confirm a significant enhancement of gamma-ray emission in the south-eastern part of the bubbles, but we do not find significant evidence for a jet. No significant variation of the spectrum across the bubbles is detected. The width of the boundary of the bubbles is estimated to be 3.4(+)3.7(-)2.6 deg. Both inverse Compton (IC) models and hadronic models including IC emission from secondary leptons t the gamma-ray data well. In the IC scenario, the synchrotron emission from the same population of electrons can also explain the WMAP and Planck microwave haze with a magnetic field between 5 and 20 micro-G.

318 citations


Journal ArticleDOI
TL;DR: In this article, the authors provide detailed documentation of the iron abundance determination of the 34 FGK-type benchmark stars that are selected to be the pillars for calibration of the one billion Gaia stars.
Abstract: Context. To calibrate automatic pipelines that determine atmospheric parameters of stars, one needs a sample of stars, or “benchmark stars”, with well-defined parameters to be used as a reference.Aims. We provide detailed documentation of the iron abundance determination of the 34 FGK-type benchmark stars that are selected to be the pillars for calibration of the one billion Gaia stars. They cover a wide range of temperatures, surface gravities, and metallicities.Methods. Up to seven different methods were used to analyze an observed spectral library of high resolutions and high signal-to-noise ratios. The metallicity was determined by assuming a value of effective temperature and surface gravity obtained from fundamental relations; that is, these parameters were known a priori and independently from the spectra.Results. We present a set of metallicity values obtained in a homogeneous way for our sample of benchmark stars. In addition to this value, we provide detailed documentation of the associated uncertainties. Finally, we report a value of the metallicity of the cool giant ψ Phe for the first time.

Journal ArticleDOI
Markus Ackermann, Marco Ajello1, Katsuaki Asano2, W. B. Atwood3  +215 moreInstitutions (45)
03 Jan 2014-Science
TL;DR: Temporal and spectral analyses of GRB 130427A challenge the widely accepted model that the nonthermal high-energy emission in the afterglow phase of GRBs is synchrotron emission radiated by electrons accelerated at an external shock.
Abstract: The observations of the exceptionally bright gamma-ray burst (GRB) 130427A by the Large Area Telescope aboard the Fermi Gamma-ray Space Telescope provide constraints on the nature of these unique astrophysical sources. GRB 130427A had the largest fluence, highest-energy photon (95 GeV), longest gamma-ray duration (20 hours), and one of the largest isotropic energy releases ever observed from a GRB. Temporal and spectral analyses of GRB 130427A challenge the widely accepted model that the nonthermal high-energy emission in the afterglow phase of GRBs is synchrotron emission radiated by electrons accelerated at an external shock.

Journal ArticleDOI
TL;DR: The proposed similarity measure soft similarity is a generalize of the well-known cosine similarity measure in VSM by introducing what it is called “soft cosine measure” and various formulas for exact or approximate calculation of the softcosine measure are proposed.
Abstract: We show how to consider similarity between features for calculation of similarity of objects in the Vector Space Model (VSM) for machine learning algorithms and other classes of methods that involve similarity between objects. Unlike LSA, we assume that similarity between features is known (say, from a synonym dictionary) and does not need to be learned from the data.We call the proposed similarity measure soft similarity. Similarity between features is common, for example, in natural language processing: words, n-grams, or syntactic n-grams can be somewhat different (which makes them different features) but still have much in common: for example, words “play” and “game” are different but related. When there is no similarity between features then our soft similarity measure is equal to the standard similarity. For this, we generalize the well-known cosine similarity measure in VSM by introducing what we call “soft cosine measure”. We propose various formulas for exact or approximate calculation of the soft cosine measure. For example, in one of them we consider for VSM a new feature space consisting of pairs of the original features weighted by their similarity. Again, for features that bear no similarity to each other, our formulas reduce to the standard cosine measure. Our experiments show that our soft cosine measure provides better performance in our case study: entrance exams question answering task at CLEF. In these experiments, we use syntactic n-grams as features and Levenshtein distance as the similarity between n-grams, measured either in characters or in elements of n-grams.

Journal ArticleDOI
TL;DR: This review summarises the use of essential oils in the control of postharvest diseases of horticultural commodities, their mode of actions, effects on the defence mechanism and quality of fresh fruit.

Journal ArticleDOI
TL;DR: An advanced information centric platform for supporting the typical ICT services of a Smart City that can easily embrace all available and upcoming wireless technologies, while enforcing, at the same time, ubiquitous and secure applications in many domains.

Journal ArticleDOI
TL;DR: Sn-grams can be applied in any natural language processing (NLP) task where traditional n- grams are used and described how sn-rams were applied to authorship attribution.
Abstract: In this paper we introduce and discuss a concept of syntactic n-grams (sn-grams). Sn-grams differ from traditional n-grams in the manner how we construct them, i.e., what elements are considered neighbors. In case of sn-grams, the neighbors are taken by following syntactic relations in syntactic trees, and not by taking words as they appear in a text, i.e., sn-grams are constructed by following paths in syntactic trees. In this manner, sn-grams allow bringing syntactic knowledge into machine learning methods; still, previous parsing is necessary for their construction. Sn-grams can be applied in any natural language processing (NLP) task where traditional n-grams are used. We describe how sn-grams were applied to authorship attribution. We used as baseline traditional n-grams of words, part of speech (POS) tags and characters; three classifiers were applied: support vector machines (SVM), naive Bayes (NB), and tree classifier J48. Sn-grams give better results with SVM classifier.

Journal ArticleDOI
TL;DR: In this paper, a comprehensive overview of the evolution of a specific type of eco-innovations that are playing a crucial role in the current socioeconomic agenda, namely low-carbon energy technologies is presented.

Journal ArticleDOI
TL;DR: The present review had as its objective the collecting of data based on research conducted into some fruits and plants, which are consumed frequently by humans and which have demonstrated hepatoprotective capacity, as well as an analysis of a resin and some phytochemicals extracted from fruits, plants, yeasts, and algae.
Abstract: The liver is one of the most important organs in the body, performing a fundamental role in the regulation of diverse processes, among which the metabolism, secretion, storage, and detoxification of endogenous and exogenous substances are prominent. Due to these functions, hepatic diseases continue to be among the main threats to public health, and they remain problems throughout the world. Despite enormous advances in modern medicine, there are no completely effective drugs that stimulate hepatic function, that offer complete protection of the organ, or that help to regenerate hepatic cells. Thus, it is necessary to identify pharmaceutical alternatives for the treatment of liver diseases, with the aim of these alternatives being more effective and less toxic. The use of some plants and the consumption of different fruits have played basic roles in human health care, and diverse scientific investigations have indicated that, in those plants and fruits so identified, their beneficial effects can be attributed to the presence of chemical compounds that are called phytochemicals. The present review had as its objective the collecting of data based on research conducted into some fruits (grapefruit, cranberries, and grapes) and plants [cactus pear (nopal) and cactus pear fruit, chamomile, silymarin, and spirulina], which are consumed frequently by humans and which have demonstrated hepatoprotective capacity, as well as an analysis of a resin (propolis) and some phytochemicals extracted from fruits, plants, yeasts, and algae, which have been evaluated in different models of hepatotoxicity.

Proceedings ArticleDOI
01 Aug 2014
TL;DR: This work aims to solve the problem of aspect extraction from product reviews by proposing a novel rule-based approach that exploits common-sense knowledge and sentence dependency trees to detect both explicit and implicit aspects.
Abstract: Sentiment analysis is a rapidly growing research field that has attracted both academia and industry because of the challenging research problems it poses and the potential benefits it can provide in many real life applications. Aspect-based opinion mining, in particular, is one of the fundamental challenges within this research field. In this work, we aim to solve the problem of aspect extraction from product reviews by proposing a novel rule-based approach that exploits common-sense knowledge and sentence dependency trees to detect both explicit and implicit aspects. Two popular review datasets were used for evaluating the system against state-of-the-art aspect extraction techniques, obtaining higher detection accuracy for both datasets.

Journal ArticleDOI
S. Chatrchyan1, Vardan Khachatryan1, Albert M. Sirunyan1, Armen Tumasyan1  +2230 moreInstitutions (144)
TL;DR: The observed (expected) upper limit on the invisible branching fraction at 0.58 (0.44) is interpreted in terms of a Higgs-portal model of dark matter interactions.
Abstract: A search for invisible decays of Higgs bosons is performed using the vector boson fusion and associated ZH production modes. In the ZH mode, the Z boson is required to decay to a pair of charged leptons or a $b\bar{b}$ quark pair. The searches use the 8 TeV pp collision dataset collected by the CMS detector at the LHC, corresponding to an integrated luminosity of up to 19.7 inverse femtobarns. Certain channels include data from 7 TeV collisions corresponding to an integrated luminosity of 4.9 inverse femtobarns. The searches are sensitive to non-standard-model invisible decays of the recently observed Higgs boson, as well as additional Higgs bosons with similar production modes and large invisible branching fractions. In all channels, the observed data are consistent with the expected standard model backgrounds. Limits are set on the production cross section times invisible branching fraction, as a function of the Higgs boson mass, for the vector boson fusion and ZH production modes. By combining all channels, and assuming standard model Higgs boson cross sections and acceptances, the observed (expected) upper limit on the invisible branching fraction at $m_H$=125 GeV is found to be 0.58 (0.44) at 95% confidence level. We interpret this limit in terms of a Higgs-portal model of dark matter interactions.

Journal ArticleDOI
A. Aab1, P. Abreu2, Marco Aglietta3, E. J. Ahn4  +481 moreInstitutions (53)
TL;DR: In this article, the authors examined the implications of the distributions of the depths of atmospheric shower maximum (X-max) using a hybrid technique, for composition and hadronic interaction models, and found that their data are not well described by a mix of protons and iron nuclei over most of the energy range.
Abstract: Using the data taken at the Pierre Auger Observatory between December 2004 and December 2012, we have examined the implications of the distributions of depths of atmospheric shower maximum (X-max), using a hybrid technique, for composition and hadronic interaction models. We do this by fitting the distributions with predictions from a variety of hadronic interaction models for variations in the composition of the primary cosmic rays and examining the quality of the fit. Regardless of what interaction model is assumed, we find that our data are not well described by a mix of protons and iron nuclei over most of the energy range. Acceptable fits can be obtained when intermediate masses are included, and when this is done consistent results for the proton and iron-nuclei contributions can be found using the available models. We observe a strong energy dependence of the resulting proton fractions, and find no support from any of the models for a significant contribution from iron nuclei. However, we also observe a significant disagreement between the models with respect to the relative contributions of the intermediate components.

Journal ArticleDOI
TL;DR: This study provides important information on the identification and utilization of Mexican seaweed resources for agriculture and is the first study to report on the uses of these seaweeds as a source of liquid extracts as biostimulants in agriculture.
Abstract: Seaweed extracts are used as nutrient supplements, biostimulants, or biofertilizers in agriculture and horticulture to increase plant growth and yield. In this study, we examined the effect of liquid seaweed extracts (LSEs) made from Ulva lactuca, Caulerpa sertularioides, Padina gymnospora, and Sargassum liebmannii as biostimulants on the germination and growth of tomato (Solanum lycopersicum) under laboratory and greenhouse conditions using foliar and soil drench applications of LSEs. We assessed LSEs at different concentrations (0.2, 0.4, and 1.0 %) on germination parameters (percentage, index, mean time, energy, and seedling vigor index) and growth parameters (plumule length, radical length, shoot length, root length, fresh weight, and dry weight) of tomato seedlings. Our results indicate that seeds treated with LSEs of U. lactuca and P. gymnospora at lower concentrations (0.2 %) showed enhanced germination (better response in germination rate associated with lower mean germination time, high germination index and germination energy, and consequently greater seedling vigor and greater plumule and radicle length). Application as a soil drench was found to be more effective in influencing the height of the plant (up to 79 cm) than the foliar spray application (75 cm). Plants receiving LSEs of U. lactuca and P. gymnospora showed increased shoot length, root length, and weight. Furthermore, U. lactuca and P. gymnospora were found to be more successful and better candidates for developing effective biostimulants to improve the growth of tomato plants. This study provides important information on the identification and utilization of Mexican seaweed resources for agriculture and is the first study to report on the uses of these seaweeds as a source of liquid extracts as biostimulants in agriculture.

Journal ArticleDOI
TL;DR: In this paper, the authors used the atmospheric parameters, [alpha/Fe] abundances, and radial velocities, which were determined from the Gaia-ESO Survey GIRAFFE spectra of FGK-type stars, to provide a chemo-kinematical characterisation of the disc stellar populations.
Abstract: Aims. The nature of the thick disc and its relation to the thin disc is presently an important subject of debate. In fact, the structural and chemo-dynamical transition between disc populations can be used as a test of the proposed models of Galactic disc formation and evolution. Methods. We used the atmospheric parameters, [alpha/Fe] abundances, and radial velocities, which were determined from the Gaia-ESO Survey GIRAFFE spectra of FGK-type stars (first nine months of observations) to provide a chemo-kinematical characterisation of the disc stellar populations. We focussed on a subsample of 1016 stars with high-quality parameters, covering the volume vertical bar Z vertical bar < 4.5 kpc and R in the range 2-13 kpc. Results. We have identified a thin to thick disc separation in the [alpha/Fe] vs. [M/H] plane, thanks to the presence of a low-density region in the number density distribution. The thick disc stars seem to lie in progressively thinner layers above the Galactic plane, as metallicity increases and [alpha/Fe] decreases. In contrast, the thin disc population presents a constant value of the mean distance to the Galactic plane at all metallicities. In addition, our data confirm the already known correlations between V-phi and [M/H] for the two discs. For the thick disc sequence, a study of the possible contamination by thin disc stars suggests a gradient up to 64 +/- 9 km s(-1) dex(-1). The distributions of azimuthal velocity, vertical velocity, and orbital parameters are also analysed for the chemically separated samples. Concerning the gradients with galactocentric radius, we find, for the thin disc, a flat behaviour of the azimuthal velocity, a metallicity gradient equal to -0.058 +/- 0.008 dex kpc(-1) and a very small positive [alpha/Fe] gradient. For the thick disc, flat gradients in [M/H] and [alpha/Fe] are derived. Conclusions. Our chemo-kinematical analysis suggests a picture where the thick disc seems to have experienced a settling process, during which its rotation increased progressively and, possibly, the azimuthal velocity dispersion decreased. At [M/H] approximate to -0.25 dex and [alpha/Fe] approximate to 0.1 dex, the mean characteristics of the thick disc in vertical distance to the Galactic plane, rotation, rotational dispersion, and stellar orbits' eccentricity agree with that of the thin disc stars of the same metallicity, suggesting a possible connection between these two populations at a certain epoch of the disc evolution. Finally, the results presented here, based only on the first months of the Gaia-ESO Survey observations, confirm how crucial large high-resolution spectroscopic surveys outside the solar neighbourhood are today for our understanding of the Milky Way history.

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Rodolfo Smiljanic1, Andreas Korn2, Maria Bergemann3, Antonio Frasca4, Laura Magrini4, Thomas Masseron5, Elena Pancino6, Gregory R. Ruchti7, I. San Roman8, Luca Sbordone9, Luca Sbordone10, Luca Sbordone11, S. G. Sousa12, Hugo M. Tabernero13, Gražina Tautvaišienė14, Marica Valentini15, Michael Weber15, Clare Worley16, V. Zh. Adibekyan12, C. Allende Prieto17, C. Allende Prieto18, G. Barisevičius14, K. Biazzo4, S. Blanco-Cuaresma19, Piercarlo Bonifacio20, Angela Bragaglia4, Elisabetta Caffau11, Elisabetta Caffau20, Tristan Cantat-Gaudin21, Y. Chorniy14, P. de Laverny19, E. Delgado-Mena12, P. Donati22, S. Duffau11, S. Duffau9, S. Duffau10, E. Franciosini4, Eileen D. Friel23, Douglas Geisler8, J. I. González Hernández18, Pieter Gruyters2, Guillaume Guiglion19, Camilla Juul Hansen11, Ulrike Heiter2, Vanessa Hill19, Heather R. Jacobson24, Paula Jofre16, Henrik Jönsson7, A. C. Lanzafame25, Carmela Lardo4, Hans-Günter Ludwig11, Enrico Maiorca4, S. Mikolaitis14, S. Mikolaitis19, D. Montes13, Thierry Morel26, Alessio Mucciarelli22, C. Muñoz8, Thomas Nordlander2, L. Pasquini1, E. Puzeras14, Alejandra Recio-Blanco19, Nils Ryde7, G. G. Sacco4, Nuno C. Santos12, Aldo Serenelli18, R. Sordo4, Caroline Soubiran19, Lorenzo Spina4, Lorenzo Spina27, Matthias Steffen15, Antonella Vallenari4, S. Van Eck5, S. Villanova8, Gerard Gilmore16, Sofia Randich4, Martin Asplund28, James Binney, Janet E. Drew29, Sofia Feltzing7, Annette M. N. Ferguson30, R. D. Jeffries31, Giuseppina Micela4, Ignacio Negueruela32, T. Prusti33, H. W. Rix3, Emilio J. Alfaro18, C. Babusiaux20, Thomas Bensby7, R. Blomme34, Ettore Flaccomio4, P. Francois20, Mike Irwin16, Sergey E. Koposov16, N. A. Walton16, Amelia Bayo35, Amelia Bayo3, Giovanni Carraro1, M. T. Costado18, Francesco Damiani24, Bengt Edvardsson2, A. Hourihane16, R. J. Jackson31, Jack Lewis16, Karin Lind16, Gianni Marconi1, Christophe Martayan1, Lorenzo Monaco1, L. Morbidelli4, L. Prisinzano4, Simone Zaggia4 
TL;DR: In this article, the Gaia-ESO Public Spectroscopic Survey is using FLAMES at the VLT to obtain high-quality medium-resolution Giraffe spectra for about 10(5) stars and high-resolution UVES spectra of about 5000 stars.
Abstract: Context. The ongoing Gaia-ESO Public Spectroscopic Survey is using FLAMES at the VLT to obtain high-quality medium-resolution Giraffe spectra for about 10(5) stars and high-resolution UVES spectra for about 5000 stars. With UVES, the Survey has already observed 1447 FGK-type stars. Aims. These UVES spectra are analyzed in parallel by several state-of-the-art methodologies. Our aim is to present how these analyses were implemented, to discuss their results, and to describe how a final recommended parameter scale is defined. We also discuss the precision (method-to-method dispersion) and accuracy (biases with respect to the reference values) of the final parameters. These results are part of the Gaia-ESO second internal release and will be part of its first public release of advanced data products. Methods. The final parameter scale is tied to the scale defined by the Gaia benchmark stars, a set of stars with fundamental atmospheric parameters. In addition, a set of open and globular clusters is used to evaluate the physical soundness of the results. Each of the implemented methodologies is judged against the benchmark stars to define weights in three different regions of the parameter space. The final recommended results are the weighted medians of those from the individual methods. Results. The recommended results successfully reproduce the atmospheric parameters of the benchmark stars and the expected T-eff-log g relation of the calibrating clusters. Atmospheric parameters and abundances have been determined for 1301 FGK-type stars observed with UVES. The median of the method-to-method dispersion of the atmospheric parameters is 55K for T-eff, 0.13dex for log g and 0.07 dex for [Fe/H]. Systematic biases are estimated to be between 50-100 K for T-eff, 0.10-0.25 dex for log g and 0.05-0.10 dex for [Fe/H]. Abundances for 24 elements were derived: C, N, O, Na, Mg, Al, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Mo, Ba, Nd, and Eu. The typical method-to-method dispersion of the abundances varies between 0.10 and 0.20 dex. Conclusions. The Gaia-ESO sample of high-resolution spectra of FGK-type stars will be among the largest of its kind analyzed in a homogeneous way. The extensive list of elemental abundances derived in these stars will enable significant advances in the areas of stellar evolution and Milky Way formation and evolution.

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TL;DR: In this article, the authors provide an overview of the main catalytic studies of H2 production by ethanol steam reforming (ESR) in terms of selectivity and selectivity to H2.

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TL;DR: In this article, the relationship between age, metallicity, and alpha enhancement of FGK stars in the Galactic disk was studied based on the analysis of high-resolution UVES spectra from the Gaia-ESO large stellar survey.
Abstract: We study the relationship between age, metallicity, and alpha-enhancement of FGK stars in the Galactic disk. The results are based upon the analysis of high-resolution UVES spectra from the Gaia-ESO large stellar survey. We explore the limitations of the observed dataset, i.e. the accuracy of stellar parameters and the selection effects that are caused by the photometric target preselection. We find that the colour and magnitude cuts in the survey suppress old metal-rich stars and young metal-poor stars. This suppression may be as high as 97% in some regions of the age-metallicity relationship. The dataset consists of 144 stars with a wide range of ages from 0.5 Gyr to 13.5 Gyr, Galactocentric distances from 6 kpc to 9.5 kpc, and vertical distances from the plane 0 9 Gyr is not as small as advocated by some other studies. In agreement with earlier work, we find that radial abundance gradients change as a function of vertical distance from the plane. The [Mg/Fe] gradient steepens and becomes negative. In addition, we show that the inner disk is not only more alpha-rich compared to the outer disk, but also older, as traced independently by the ages and Mg abundances of stars.

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TL;DR: A review of the field of cationic UV-curing can be found in this paper, where a large number of papers and patents are reviewed and critically discussed specifically with respect to the application of CVD technology in the fields of coatings, composites, adhesives, and inks.
Abstract: This paper reviews the field of cationic UV-curing and reports recent progress made in understanding the fundamental chemistry and in technology applications. Radiation curing technologies are expanding rapidly on an industrial scale and interest in cationic photopolymerizations has advanced rapidly. In particular, the cationic UV-curing process presents additional benefits, including: the absence of air inhibition, a “dark-curing” reaction, low levels of toxicity and irritation, and a lower volume shrinkage during photopolymerization. In this review, a large number of papers and patents are reviewed and critically discussed specifically with respect to the application of cationic UV-curing technology in the field of coatings, composites, adhesives, and inks.

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TL;DR: A search for neutral Higgs bosons in the minimal supersymmetric extension of the standard model (MSSM) decaying to tau-lepton pairs in pp collisions is performed, using events recorded by the CMS experiment at the LHC.
Abstract: A search for neutral Higgs bosons in the minimal supersymmetric extension of the standard model (MSSM) decaying to tau-lepton pairs in pp collisions is performed, using events recorded by the CMS experiment at the LHC. The dataset corresponds to an integrated luminosity of 24.6 fb^(−1), with 4.9 fb^(−1) at 7 TeV and 19.7 fb^(−1) at 8 TeV. To enhance the sensitivity to neutral MSSM Higgs bosons, the search includes the case where the Higgs boson is produced in association with a b-quark jet. No excess is observed in the tau-lepton-pair invariant mass spectrum. Exclusion limits are presented in the MSSM parameter space for different benchmark scenarios, m_h^(max), m_h^(mod)_ +, m_h^(mod)_ -, light-stop, light-stau, τ-phobic, and low-m_H. Upper limits on the cross section times branching fraction for gluon fusion and b-quark associated Higgs boson production are also given.

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TL;DR: In this article, the current knowledge of methanogenesis and methanotrophy in soils, anaerobic CH 4 oxidation, in extreme environments is also discussed, as well as the current state of the art in the CH 4 cycle.

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TL;DR: In this paper, a review of the literature covering the various types of interfaces developed for electrochemical energy storage systems is presented, including standard, multilevel and multiport technology.