Showing papers by "Instituto Politécnico Nacional published in 2015"
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TL;DR: The different metrics of urban smartness are reviewed to show the need for a shared definition of what constitutes a smart city, what are its features, and how it performs in comparison to traditional cities.
Abstract: As the term “smart city” gains wider and wider currency, there is still confusion about what a smart city is, especially since several similar terms are often used interchangeably. This paper aims to clarify the meaning of the word “smart” in the context of cities through an approach based on an in-depth literature review of relevant studies as well as official documents of international institutions. It also identifies the main dimensions and elements characterizing a smart city. The different metrics of urban smartness are reviewed to show the need for a shared definition of what constitutes a smart city, what are its features, and how it performs in comparison to traditional cities. Furthermore, performance measures and initiatives in a few smart cities are identified.
2,207 citations
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TL;DR: A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4ℓ decay channels.
Abstract: A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4l decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two experiments. The measured masses from the individual channels and the two experiments are found to be consistent among themselves. The combined measured mass of the Higgs boson is mH=125.09±0.21 (stat)±0.11 (syst) GeV.
1,567 citations
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TL;DR: In this article, the authors present the main research challenges and the existing solutions in the field of IoT security, identifying open issues and suggesting some hints for future research, and suggest some hints to future research.
1,258 citations
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SLAC National Accelerator Laboratory1, Stockholm University2, Santa Cruz Institute for Particle Physics3, Istituto Nazionale di Fisica Nucleare4, University of Wisconsin-Madison5, Goddard Space Flight Center6, University of Montpellier7, École Polytechnique8, INAF9, George Mason University10, University of Padua11, Instituto Politécnico Nacional12, Fermilab13, C. N. Yang Institute for Theoretical Physics14, Hiroshima University15, Paris Diderot University16, University of Göttingen17, University of North Florida18, University of Iceland19, Spanish National Research Council20, University of Maryland, College Park21, University of California, Irvine22, University of Denver23, Stony Brook University24, Texas A&M University25, Ohio State University26, United States Naval Research Laboratory27
TL;DR: In this article, the authors report on γ-ray observations of the Milky-Way satellite galaxies (dSphs) based on six years of Fermi Large Area Telescope data processed with the new Pass8 event-level analysis.
Abstract: The dwarf spheroidal satellite galaxies (dSphs) of the Milky Way are some of the most dark matter (DM) dominated objects known. We report on γ-ray observations of Milky Way dSphs based on six years of Fermi Large Area Telescope data processed with the new Pass8 event-level analysis. None of the dSphs are significantly detected in γ rays, and we present upper limits on the DM annihilation cross section from a combined analysis of 15 dSphs. These constraints are among the strongest and most robust to date and lie below the canonical thermal relic cross section for DM of mass ≲100 GeV annihilating via quark and τ-lepton channels.
1,166 citations
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TL;DR: It is found that the Néel skyrmion moved by the spin-Hall effect is a very promising strategy for technological implementation of the next generation of skyrMion racetrack memories (zero field, high thermal stability, and ultra-dense storage).
Abstract: Magnetic storage based on racetrack memory is very promising for the design of ultra-dense, low-cost and low-power storage technology. Information can be coded in a magnetic region between two domain walls or, as predicted recently, in topological magnetic objects known as skyrmions. Here, we show the technological advantages and limitations of using Bloch and Neel skyrmions manipulated by spin current generated within the ferromagnet or via the spin-Hall effect arising from a non-magnetic heavy metal underlayer. We found that the Neel skyrmion moved by the spin-Hall effect is a very promising strategy for technological implementation of the next generation of skyrmion racetrack memories (zero field, high thermal stability, and ultra-dense storage). We employed micromagnetics reinforced with an analytical formulation of skyrmion dynamics that we developed from the Thiele equation. We identified that the excitation, at high currents, of a breathing mode of the skyrmion limits the maximal velocity of the memory.
832 citations
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TL;DR: Evidence indicates that motor competence is positively associated with perceived competence and multiple aspects of health, but questions related to the increased strength of associations across time and antecedent/consequent mechanisms remain.
Abstract: In 2008, Stodden and colleagues took a unique developmental approach toward addressing the potential role of motor competence in promoting positive or negative trajectories of physical activity, health-related fitness, and weight status. The conceptual model proposed synergistic relationships among physical activity, motor competence, perceived motor competence, health-related physical fitness, and obesity with associations hypothesized to strengthen over time. At the time the model was proposed, limited evidence was available to support or refute the model hypotheses. Over the past 6 years, the number of investigations exploring these relationships has increased significantly. Thus, it is an appropriate time to examine published data that directly or indirectly relate to specific pathways noted in the conceptual model. Evidence indicates that motor competence is positively associated with perceived competence and multiple aspects of health (i.e., physical activity, cardiorespiratory fitness, muscular strength, muscular endurance, and a healthy weight status). However, questions related to the increased strength of associations across time and antecedent/consequent mechanisms remain. An individual’s physical and psychological development is a complex and multifaceted process that synergistically evolves across time. Understanding the most salient factors that influence health and well-being and how relationships among these factors change across time is a critical need for future research in this area. This knowledge could aid in addressing the declining levels of physical activity and fitness along with the increasing rates of obesity across childhood and adolescence.
759 citations
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TL;DR: The first IGRB measurement with the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope (Fermi) used 10 months of sky-survey data and considered an energy range between 200 MeV and 100 GeV.
Abstract: The gamma-ray sky can be decomposed into individually detected sources, diffuse emission attributed to the interactions of Galactic cosmic rays with gas and radiation fields, and a residual all-sky emission component commonly called the isotropic diffuse gamma-ray background (IGRB). The IGRB comprises all extragalactic emissions too faint or too diffuse to be resolved in a given survey, as well as any residual Galactic foregrounds that are approximately isotropic. The first IGRB measurement with the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope (Fermi) used 10 months of sky-survey data and considered an energy range between 200 MeV and 100 GeV. Improvements in event selection and characterization of cosmic-ray backgrounds, better understanding of the diffuse Galactic emission, and a longer data accumulation of 50 months, allow for a refinement and extension of the IGRB measurement with the LAT, now covering the energy range from 100 MeV to 820 GeV. The IGRB spectrum shows a significant high-energy cutoff feature, and can be well described over nearly four decades in energy by a power law with exponential cutoff having a spectral index of 2.32 plus or minus 0.02 and a break energy of (279 plus or minus 52) GeV using our baseline diffuse Galactic emission model. The total intensity attributed to the IGRB is (7.2 plus or minus 0.6) x 10(exp -6) cm(exp -2) s(exp -1) sr(exp -1) above 100 MeV, with an additional +15%/-30% systematic uncertainty due to the Galactic diffuse foregrounds.
680 citations
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TL;DR: The third catalog of active galactic nuclei (AGNs) detected by the Fermi-LAT (3LAC) is presented in this paper, which is based on the 3FGL of sources detected between 100 MeV and 300 GeV.
Abstract: The third catalog of active galactic nuclei (AGNs) detected by the Fermi-LAT (3LAC) is presented. It is based on the third Fermi-LAT catalog (3FGL) of sources detected between 100 MeV and 300 GeV w ...
668 citations
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21 Oct 2015-Nuclear Instruments & Methods in Physics Research Section A-accelerators Spectrometers Detectors and Associated Equipment
TL;DR: The Pierre Auger Observatory as mentioned in this paper, the world's largest cosmic ray observatory, has been in successful operation since completion in 2008 and has recorded data from an exposure exceeding 40,000 km$^2$ sr yr.
Abstract: The Pierre Auger Observatory, located on a vast, high plain in western Argentina, is the world's largest cosmic ray observatory. The objectives of the Observatory are to probe the origin and characteristics of cosmic rays above $10^{17}$ eV and to study the interactions of these, the most energetic particles observed in nature. The Auger design features an array of 1660 water-Cherenkov particle detector stations spread over 3000 km$^2$ overlooked by 24 air fluorescence telescopes. In addition, three high elevation fluorescence telescopes overlook a 23.5 km$^2$, 61 detector infill array. The Observatory has been in successful operation since completion in 2008 and has recorded data from an exposure exceeding 40,000 km$^2$ sr yr. This paper describes the design and performance of the detectors, related subsystems and infrastructure that make up the Auger Observatory.
615 citations
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Vardan Khachatryan1, Albert M. Sirunyan1, Armen Tumasyan1, Wolfgang Adam2 +2802 more•Institutions (215)
TL;DR: In this paper, the branching fractions of the B meson (B-s(0)) and the B-0 meson decaying into two oppositely charged muons (mu(+) and mu(-)) were observed.
Abstract: The standard model of particle physics describes the fundamental particles and their interactions via the strong, electromagnetic and weak forces. It provides precise predictions for measurable quantities that can be tested experimentally. The probabilities, or branching fractions, of the strange B meson (B-s(0)) and the B-0 meson decaying into two oppositely charged muons (mu(+) and mu(-)) are especially interesting because of their sensitivity to theories that extend the standard model. The standard model predicts that the B-s(0)->mu(+)mu(-) and B-0 ->mu(+)mu(-) decays are very rare, with about four of the former occurring for every billion B-s(0) mesons produced, and one of the latter occurring for every ten billion B-0 mesons(1). A difference in the observed branching fractions with respect to the predictions of the standard model would provide a direction in which the standard model should be extended. Before the Large Hadron Collider (LHC) at CERN2 started operating, no evidence for either decay mode had been found. Upper limits on the branching fractions were an order of magnitude above the standard model predictions. The CMS (Compact Muon Solenoid) and LHCb(Large Hadron Collider beauty) collaborations have performed a joint analysis of the data from proton-proton collisions that they collected in 2011 at a centre-of-mass energy of seven teraelectronvolts and in 2012 at eight teraelectronvolts. Here we report the first observation of the B-s(0)->mu(+)mu(-) decay, with a statistical significance exceeding six standard deviations, and the best measurement so far of its branching fraction. Furthermore, we obtained evidence for the B-0 ->mu(+)mu(-) decay with a statistical significance of three standard deviations. Both measurements are statistically compatible with standard model predictions and allow stringent constraints to be placed on theories beyond the standard model. The LHC experiments will resume taking data in 2015, recording proton-proton collisions at a centre-of-mass energy of 13 teraelectronvolts, which will approximately double the production rates of B-s(0) and B-0 mesons and lead to further improvements in the precision of these crucial tests of the standard model.
467 citations
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TL;DR: In this paper, the authors used the Hummers method to estimate the oxidation degree of graphene oxide (GO) powders through the relative intensity of the infrared absorption bands related to oxygen containing groups.
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TL;DR: A critical review on the processing and application of rice husks (RHs) for the production of various silicon-based materials and of active carbon is presented in this paper, which addresses the different processing methods, the effects of various process parameters on the pyrolysis stage, the influence of physical, chemical and thermal treatments, activating conditions and activated carbon consolidation mechanisms.
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TL;DR: The maintenance of a rich and diversified autochthonous soil microbiota and the use of treated wastewater with minimal levels of potential soil contaminants are proposed as sine qua non conditions to achieve a sustainable wastewater reuse for irrigation.
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TL;DR: This review highlights the broad range of science that has arisen from the synthesis of coumarin-linked and fused heterocycle derivatives and their synthesis and biological activity.
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J. W. Ferry Slik, Víctor Arroyo-Rodríguez1, Shin-ichiro Aiba2, Patricia Alvarez-Loayza3 +173 more•Institutions (74)
TL;DR: It is shown that most tree species are extremely rare, meaning that they may be under serious risk of extinction at current deforestation rates, and a methodological framework for estimating species richness in trees is provided that may help refine species richness estimates of tree-dependent taxa.
Abstract: The high species richness of tropical forests has long been recognized, yet there remains substantial uncertainty regarding the actual number of tropical tree species. Using a pantropical tree inventory database from closed canopy forests, consisting of 657,630 trees belonging to 11,371 species, we use a fitted value of Fisher's alpha and an approximate pantropical stem total to estimate the minimum number of tropical forest tree species to fall between similar to 40,000 and similar to 53,000, i.e., at the high end of previous estimates. Contrary to common assumption, the Indo-Pacific region was found to be as species-rich as the Neotropics, with both regions having a minimum of similar to 19,000-25,000 tree species. Continental Africa is relatively depauperate with a minimum of similar to 4,500-6,000 tree species. Very few species are shared among the African, American, and the Indo-Pacific regions. We provide a methodological framework for estimating species richness in trees that may help refine species richness estimates of tree-dependent taxa.
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TL;DR: In this article, the physics potential of a long baseline neutrino experiment using the Hyper-Kamiokande detector and neutrinos from the J-PARC proton synchrotron is presented.
Abstract: Hyper-Kamiokande will be a next generation underground water Cherenkov detector with a total (fiducial) mass of 0.99 (0.56) million metric tons, approximately 20 (25) times larger than that of Super-Kamiokande. One of the main goals of Hyper-Kamiokande is the study of $CP$ asymmetry in the lepton sector using accelerator neutrino and anti-neutrino beams. In this paper, the physics potential of a long baseline neutrino experiment using the Hyper-Kamiokande detector and a neutrino beam from the J-PARC proton synchrotron is presented. The analysis uses the framework and systematic uncertainties derived from the ongoing T2K experiment. With a total exposure of 7.5 MW $\times$ 10$^7$ sec integrated proton beam power (corresponding to $1.56\times10^{22}$ protons on target with a 30 GeV proton beam) to a $2.5$-degree off-axis neutrino beam, it is expected that the leptonic $CP$ phase $\delta_{CP}$ can be determined to better than 19 degrees for all possible values of $\delta_{CP}$, and $CP$ violation can be established with a statistical significance of more than $3\,\sigma$ ($5\,\sigma$) for $76\%$ ($58\%$) of the $\delta_{CP}$ parameter space. Using both $
u_e$ appearance and $
u_\mu$ disappearance data, the expected 1$\sigma$ uncertainty of $\sin^2\theta_{23}$ is 0.015(0.006) for $\sin^2\theta_{23}=0.5(0.45)$.
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TL;DR: In this paper, the authors presented the best sensitivity and angular resolution maps of the molecular disk and outflow of Mrk 231, as traced by CO(2−1) and (3−2) observations obtained with the IRAM/PdBI.
Abstract: Mrk 231 is a nearby ultra-luminous IR galaxy exhibiting a kpc-scale, multi-phase AGN-driven outflow. This galaxy represents the best target to investigate in detail the morphology and energetics of powerful outflows, as well as their still poorly-understood expansion mechanism and impact on the host galaxy. In this work, we present the best sensitivity and angular resolution maps of the molecular disk and outflow of Mrk 231, as traced by CO(2−1) and (3−2) observations obtained with the IRAM/PdBI. In addition, we analyze archival deep Chandra and NuSTAR X-ray observations. We use this unprecedented combination of multi-wavelength data sets to constrain the physical properties of both the molecular disk and outflow, the presence of a highly-ionized ultra-fast nuclear wind, and their connection. The molecular CO(2−1) outflow has a size of ~1 kpc, and extends in all directions around the nucleus, being more prominent along the south-west to north-east direction, suggesting a wide-angle biconical geometry. The maximum projected velocity of the outflow is nearly constant out to ~1 kpc, thus implying that the density of the outflowing material must decrease from the nucleus outwards as ~r-2. This suggests that either a large part of the gas leaves the flow during its expansion or that the bulk of the outflow has not yet reached out to ~1 kpc, thus implying a limit on its age of ~1 Myr. Mapping the mass and energy rates of the molecular outflow yields OF = [500−1000] M⊙ yr-1 and Ėkin,OF = [7−10] × 10^(43) erg s^(-1). The total kinetic energy of the outflow is Ekin,OF is of the same order of the total energy of the molecular disk, Edisk. Remarkably, our analysis of the X-ray data reveals a nuclear ultra-fast outflow (UFO) with velocity −20 000 km s^(-1), UFO = [0.3−2.1] M_⊙ yr^(-1), and momentum load UFO/ rad = [0.2−1.6]. We find Ėkin,UFO ~ Ėkin,OF as predicted for outflows undergoing an energy conserving expansion. This suggests that most of the UFO kinetic energy is transferred to mechanical energy of the kpc-scale outflow, strongly supporting that the energy released during accretion of matter onto super-massive black holes is the ultimate driver of giant massive outflows. The momentum flux OF derived for the large scale outflows in Mrk 231 enables us to estimate a momentum boost OF/ UFO ≈ [30−60]. The ratios Ėkin,UFO/Lbol,AGN = [1−5] % and Ėkin,OF/Lbol,AGN = [1−3] % agree with the requirements of the most popular models of AGN feedback.
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Federal University of Rio de Janeiro1, Simon Fraser University2, National University of La Plata3, Oswaldo Cruz Foundation4, Washington University in St. Louis5, University of the Republic6, European Bioinformatics Institute7, National Institutes of Health8, Federal University of Uberlandia9, Universidade Federal de Minas Gerais10, Sao Paulo State University11, State University of Norte Fluminense12, Johns Hopkins University13, University of Notre Dame14, Universidade Federal Rural do Rio de Janeiro15, Pompeu Fabra University16, Centre national de la recherche scientifique17, University of Toronto18, Centers for Disease Control and Prevention19, Instituto Politécnico Nacional20, Florida International University21, Universidade Federal do Espírito Santo22, University of Illinois at Urbana–Champaign23, University of Santiago de Compostela24, Virginia Tech25, University of Cambridge26, University of Manitoba27
TL;DR: The first genome sequence of a nondipteran insect vector of an important human parasitic disease is described, which provides critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.
Abstract: Rhodnius prolixus not only has served as a model organism for the study of insect physiology, but also is a major vector of Chagas disease, an illness that affects approximately seven million people worldwide. We sequenced the genome of R. prolixus, generated assembled sequences covering 95% of the genome (∼ 702 Mb), including 15,456 putative protein-coding genes, and completed comprehensive genomic analyses of this obligate blood-feeding insect. Although immune-deficiency (IMD)-mediated immune responses were observed, R. prolixus putatively lacks key components of the IMD pathway, suggesting a reorganization of the canonical immune signaling network. Although both Toll and IMD effectors controlled intestinal microbiota, neither affected Trypanosoma cruzi, the causal agent of Chagas disease, implying the existence of evasion or tolerance mechanisms. R. prolixus has experienced an extensive loss of selenoprotein genes, with its repertoire reduced to only two proteins, one of which is a selenocysteine-based glutathione peroxidase, the first found in insects. The genome contained actively transcribed, horizontally transferred genes from Wolbachia sp., which showed evidence of codon use evolution toward the insect use pattern. Comparative protein analyses revealed many lineage-specific expansions and putative gene absences in R. prolixus, including tandem expansions of genes related to chemoreception, feeding, and digestion that possibly contributed to the evolution of a blood-feeding lifestyle. The genome assembly and these associated analyses provide critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.
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Vardan Khachatryan1, Robin Erbacher2, C. A. Carrillo Montoya3, Chang-Seong Moon +2154 more•Institutions (149)
TL;DR: The first direct search for lepton-flavour-violating decays of the recently discovered Higgs boson (H) is described in this paper, where the search is performed in the H→μτ_e and H→mτ_h channels, where τeτe and τ_h are tau leptons reconstructed in the electronic and hadronic decay channels, respectively.
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TL;DR: In this review the State of the Art will be presented, which includes a summary of the progress made over the past years in the knowledge of the structure and mechanism of the quinoxaline and quInoxaline derivatives, associated medical and biomedical value as well as industrial value.
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TL;DR: It was demonstrated that the BPF outperforms the APF, GPF, and the PBPF methods by reducing the computational time to find the optimal path at least by a factor of 1.59.
Abstract: The BPF proposal ensures a feasible, optimal and safe path for robot navigation.The results of BPF overcomes APF and other EAPF methods like those based in GAs.The BPF is quite faster in optimization leading to reduction in computation burden.The BPF running in parallel mode is the most suitable to fulfill local and global controllability.The BPF is capable to work in offline and online mode with static and dynamic obstacles. In this paper, optimal paths in environments with static and dynamic obstacles for a mobile robot (MR) are computed using a new method for path planning. The proposed method called Bacterial Potential Field (BPF) ensures a feasible, optimal and safe path. This novel proposal makes use of the Artificial Potential Field (APF) method with a Bacterial Evolutionary Algorithm (BEA) to obtain an enhanced flexible path planner method taking all the advantages of using the APF method, strongly reducing its disadvantages. Comparative experiments for sequential and parallel implementations of the BPF method against the classic APF method, as well as with the Pseudo-Bacterial Potential Field (PBPF) method, and with the Genetic Potential Field (GPF) method, all of them based on evolutionary computation to optimize the APF parameters, were achieved. A simulation platform that uses an MR realistic model was designed to test the path planning algorithms. In general terms, it was demonstrated that the BPF outperforms the APF, GPF, and the PBPF methods by reducing the computational time to find the optimal path at least by a factor of 1.59. These results have a positive impact in the ability of the BPF path planning method to satisfy local and global controllability in dynamic complex environments, avoiding collisions with objects that will interfere the navigation of the MR.
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Vardan Khachatryan1, Albert M. Sirunyan1, Armen Tumasyan1, Wolfgang Adam +2353 more•Institutions (181)
TL;DR: In this paper, a search for a heavy Higgs boson in the H to WW and H to ZZ decay channels is reported, based upon proton-proton collision data samples corresponding to an integrated luminosity of up to 5.1 inverse femtobarns at sqrt(s)=7 TeV and up to 19.7 inverse femto-bars at square root of 8 TeV, recorded by the CMS experiment at the CERN LHC.
Abstract: A search for a heavy Higgs boson in the H to WW and H to ZZ decay channels is reported. The search is based upon proton-proton collision data samples corresponding to an integrated luminosity of up to 5.1 inverse femtobarns at sqrt(s)=7 TeV and up to 19.7 inverse femtobarns at sqrt(s)=8 TeV, recorded by the CMS experiment at the CERN LHC. Several final states of the H to WW and H to ZZ decays are analyzed. The combined upper limit at the 95% confidence level on the product of the cross section and branching fraction exclude a Higgs boson with standard model-like couplings and decays in the range 145 < m[H] < 1000 GeV. We also interpret the results in the context of an electroweak singlet extension of the standard model.
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TL;DR: In this paper, the authors study the effect of different environmental management capabilities on a firm's market and image performance, and find that market performance is positively affected by the capabilities to implement environmental actions with a focus on energy and pollution and to develop environmental collaborations both with business and with non-business actors.
Abstract: In this paper, we seek to enhance the understanding of the link between environmental management and firm performance, so contributing to the debate of being “green and competitive”. Relying on the resource-based view, we study the effect of different environmental management capabilities on a firm's market and image performance. In particular, we analyze the capabilities to implement product and process-related environmental actions with different types of environmental focus (materials, energy, pollution) and the capabilities to develop environmental collaborations with different types of actors (both business actors and non-business actors). To this aim we conducted a survey on 122 Italian companies. Results show that market performance and image performance have partially different antecedents. Specifically, a firm's market performance is positively affected by the capabilities to implement environmental actions with a focus on energy and pollution and to develop environmental collaborations both with business and with non-business actors. On the other hand, a firm's image performance is positively affected by the capabilities to implement environmental actions with a focus on materials and to develop environmental collaborations with non-business actors. Copyright © 2013 John Wiley & Sons, Ltd and ERP Environment
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TL;DR: It is shown that NETs formation is strictly dependent on glucose and to a lesser extent on glutamine, that Glut‐1, glucose uptake, and glycolysis rate increase upon PMA stimulation, and that NET formation is inhibited by the gly colysis inhibitor, 2‐deoxy‐glucose, and to an lesser extent by the ATP synthase inhibitor oligomycin.
Abstract: As part of the innate immune response, neutrophils are at the forefront of defence against infection, resolution of inflammation and wound healing. They are the most abundant leucocytes in the peripheral blood, have a short lifespan and an estimated turnover of 1010 to 1011 cells per day. Neutrophils efficiently clear microbial infections by phagocytosis and by oxygen-dependent and oxygen-independent mechanisms. In 2004, a new neutrophil anti-microbial mechanism was described, the release of neutrophil extracellular traps (NETs) composed of DNA, histones and anti-microbial peptides. Several microorganisms, bacterial products, as well as pharmacological stimuli such as PMA, were shown to induce NETs. Neutrophils contain relatively few mitochondria, and derive most of their energy from glycolysis. In this scenario we aimed to analyse some of the metabolic requirements for NET formation. Here it is shown that NETs formation is strictly dependent on glucose and to a lesser extent on glutamine, that Glut-1, glucose uptake, and glycolysis rate increase upon PMA stimulation, and that NET formation is inhibited by the glycolysis inhibitor, 2-deoxy-glucose, and to a lesser extent by the ATP synthase inhibitor oligomycin. Moreover, when neutrophils were exposed to PMA in glucose-free medium for 3 hr, they lost their characteristic polymorphic nuclei but did not release NETs. However, if glucose (but not pyruvate) was added at this time, NET release took place within minutes, suggesting that NET formation could be metabolically divided into two phases; the first, independent from exogenous glucose (chromatin decondensation) and, the second (NET release), strictly dependent on exogenous glucose and glycolysis.
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TL;DR: In this paper, the authors investigated the antioxidant and anticholinergic properties of Galanga (Alpinia officinarum Hance) rhizome, which is a member of the ginger family (Zingiberaceae).
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TL;DR: The FTIR-ATR showed to be a good methodology to quantify the main sugar content in honey and easily adapted to routine analysis.
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TL;DR: The strain YG-24 was demonstrated as a suitable candidate to simultaneously remove both nitrogen and phosphate in wastewater treatment as well as heterotrophic ammonium nitrification coupled with fast nitrite denitrification directly.
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British Antarctic Survey1, University of Aberdeen2, Rhodes University3, Queen's University Belfast4, Hokkaido University5, National Taiwan Ocean University6, Shanghai Ocean University7, Instituto Politécnico Nacional8, Spanish National Research Council9, Department of Environment and Primary Industries10, National Marine Fisheries Service11, University of Chile12, Suffolk University13, University of Aveiro14, University of Newcastle15, National Oceanic and Atmospheric Administration16, Prince of Songkla University17, University of Tasmania18, Leibniz Institute of Marine Sciences19, South Australian Research and Development Institute20, Saga Group21, California Department of Fish and Wildlife22
TL;DR: The present overview describes all substantial squid fisheries around the globe, with special attention paid to interactions between squid fisheries and marine ecosystems including the effects of fishing gear, the role of squid in ecosystem change induced by overfishing on groundfish, and ecosystem-based fishery management.
Abstract: Some 290 species of squids comprise the order Teuthida that belongs to the molluscan Class Cephalopoda Of these, about 30-40 squid species have substantial commercial importance around the world Squid fisheries make a rather small contribution to world landings from capture fisheries relative to that of fish, but the proportion has increased steadily over the last decade, with some signs of recent leveling off The present overview describes all substantial squid fisheries around the globe The main ecological and biological features of exploited stocks, and key aspects of fisheries management are presented for each commercial species of squid worldwide The history and fishing methods used in squid fisheries are also described Special attention has been paid to interactions between squid fisheries and marine ecosystems including the effects of fishing gear, the role of squid in ecosystem change induced by overfishing on groundfish, and ecosystem-based fishery management
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University of Tokyo1, SLAC National Accelerator Laboratory2, Hiroshima University3, Clemson University4, Istituto Nazionale di Fisica Nucleare5, University of Padua6, Yale University7, California Institute of Technology8, Durham University9, University of Toulouse10, Hoffmann-La Roche11, University of California, Berkeley12, Technical University of Denmark13, Lawrence Livermore National Laboratory14, Instituto Politécnico Nacional15, Columbia University16, INAF17, Harvard University18, Aryabhatta Research Institute of Observational Sciences19
TL;DR: The results of a multiband observing campaign on the famous blazar 3C 279 conducted during a phase of increased activity from 2013 December to 2014 April, including first observations of it with NuSTAR were reported in this paper.
Abstract: We report the results of a multiband observing campaign on the famous blazar 3C 279 conducted during a phase of increased activity from 2013 December to 2014 April, including first observations of it with NuSTAR. The gamma-ray emission of the source measured by Fermi-LAT showed multiple distinct flares reaching the highest flux level measured in this object since the beginning of the Fermi mission, with F(E > 100 MeV) of 10^(-5) photons cm^(-2) s^(-1), and with a flux-doubling time scale as short as 2 hr. The gamma-ray spectrum during one of the flares was very hard, with an index of Gamma(gamma) = 1.7 +/- 0.1, which is rarely seen in flat-spectrum radio quasars. The lack of concurrent optical variability implies a very high Compton dominance parameter L-gamma/L-syn > 300. Two 1 day NuSTAR observations with accompanying Swift pointings were separated by 2 weeks, probing different levels of source activity. While the 0.5 - 70 keV X-ray spectrum obtained during the first pointing, and fitted jointly with Swift-XRT is well-described by a simple power law, the second joint observation showed an unusual spectral structure: the spectrum softens by Delta Gamma(X) similar or equal to 0.4 at similar to 4 keV. Modeling the broadband spectral energy distribution during this flare with the standard synchrotron plus inverse-Compton model requires: (1) the location of the gamma-ray emitting region is comparable with the broad-line region radius, (2) a very hard electron energy distribution index p similar or equal to 1, (3) total jet power significantly exceeding the accretion-disk luminosity L-j/L-d greater than or similar to 10, and (4) extremely low jet magnetization with L-B/L-j less than or similar to 10^(-4). We also find that single-zone models that match the observed gamma-ray and optical spectra cannot satisfactorily explain the production of X-ray emission.
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Abstract: Many authorities have reached the conclusion that using fossil fuels, as the main source of energy to satisfy the increasing global energy demand, is ultimately unsustainable. This is because of depleting resources, and also because, if this approach is followed, emissions of carbon dioxide would continue to build up. Consequently, research on biofuel, that is fuel made from biomass, derived from materials that were recently living, has attracted attention. In this context, the generation of biofuels from algae shows promise for the following reasons. The algae can be grown quickly, all the materials produced are non-toxic and biodegradable, and during this growth there is an opportunity to cause greenhouse gas fixation. Also, since growing algae does not need arable land, it can be grown without competing with food or feed crops, the fuel derived from it being a “third generation” biofuel.
This paper describes different types of algae (microalgae and seaweeds), and presents different technologies employed in making biofuels (biogas and biodiesel) from them.