International Agency for Research on Cancer

About: International Agency for Research on Cancer is a government organization based out in Lyon, France. It is known for research contribution in the topics: Cancer & Population. The organization has 2989 authors who have published 9010 publications receiving 929752 citations. The organization is also known as: IARC.

Sunscreen use and increased duration of intentional sun exposure: Still a burning issue

Abstract: Sunscreen use is often proposed for sun protection because of their ability to block UV-induced sunburns (the sun protection factor--SPF) Among suntan seekers, however, risk of cutaneous melanoma may be increased because of extended sun exposure duration We made a systematic review of the evidence linking sunscreen use to sun exposure duration Five observational studies found that when sun exposure was associated with willingness to get a tan or to stay longer in the sun (ie, intentional sun exposure), sunscreen use was associated with duration of sun exposure 13-39% longer Paradoxically, sunburns tend to be more frequent among sunscreen users, probably because of greater natural sun sensitivity When sun exposure was not intentional, sunscreen use did not increase time spent in the sun Two European double-blind randomized trials conducted among young sun seekers found daily sun exposure duration, especially sunbathing, 19-25% longer with use of SPF 30 than with use of SPF 10 sunscreens One randomized trial in a holiday resort in France found a 3-13% increase in sun exposure duration with use of SPF 12 versus SPF 40 sunscreen But, the SPF 12 groups used 36-42 more sunscreen than the SPF 40 group, and thus the actual SPF in the SPF 12 group was higher than in the SPF 40 groups In conclusion, sunscreen use leads to longer duration of sun exposure when sun exposure is intentional, but not when sun exposure is non intentional

Report on consensus conference on cervical cancer screening and management.

Abstract: Anthony B. MILLER*, Saloney NAZEER, Sharon FONN, Assia BRANDUP-LUKANOW, Rakshanda REHMAN, Hennie CRONJE, Rengaswamy SANKARANARAYANAN, Valentin KOROLTCHOUK, Kari SYRJANEN, Albert SINGER and Mathias ONSRUD on behalf of the participants Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany Department of Gynecology and Obstetrics, Hopitaux Universitaires de Geneve, Geneva, Switzerland Women’s Health Project, Johannesburg, South Africa WHO Regional Office for European Region, Copenhagen, Denmark Department of Gynecology and Obstetrics, Fatimah Jinnah Medical College, Lahore, Pakistan Department of Obstetrics and Gynecology, The University of the Orange Free State, Bloemfontein, South Africa Unit of Descriptive Epidemiology, International Agency for Research on Cancer, Lyon, France Geneva, Switzerland Department of Pathology, Central Hospital, Kuopio, Finland Department of Women’s and Children’s Health, The Whittington Hospital, London, England Department of Gynecology and Obstetrics, University Hospital of Trondheim, Norway

Genotyping by mass spectrometric analysis of short dna fragments

Abstract: Genotyping can be accomplished by analysis of short, defined DNA segments using electrospray ionization mass spectrometry. The DNA segments are produced using specially designed primers to amplify a cDNA or genomic DNA template. The primers contain a recognition site for a restriction endonuclease. The amplification products are digested with the restriction endonuclease. Single nucleotide polymorphisms can be detected rapidly and reliably.