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Institution

International Centre for Diarrhoeal Disease Research, Bangladesh

FacilityDhaka, Bangladesh
About: International Centre for Diarrhoeal Disease Research, Bangladesh is a facility organization based out in Dhaka, Bangladesh. It is known for research contribution in the topics: Population & Vibrio cholerae. The organization has 3103 authors who have published 5238 publications receiving 226880 citations. The organization is also known as: SEATO Cholera Research Laboratory & Bangladesh International Centre for Diarrhoeal Disease Research.


Papers
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Journal ArticleDOI
TL;DR: Improvement of birth weight is likely to lead to significant gains in infant nutritional status in this population, although interventions in the first 3 mo are also likely to be beneficial.

115 citations

Journal ArticleDOI
TL;DR: Household air pollution exposure was associated with a higher prevalence of COPD, particularly among women, and it is likely a leading population‐attributable risk factor for COPD in resource‐poor settings.
Abstract: Rationale: Forty percent of households worldwide burn biomass fuels for energy, which may be the most important contributor to household air pollution.Objectives: To examine the association between...

115 citations

Journal ArticleDOI
TL;DR: Different species of Aeromonas and different clones of aeromonas species seem to be associated with hospitalized cases of diarrhoea in Kolkata, India.
Abstract: A comprehensive study was performed to examine incidence, species distribution, drugs sensitivity, virulence genes and molecular fingerprints of Aeromonas species isolated from patients with acute diarrhoea over a period of 2 years in Kolkata, India. Following the Aerokey II scheme, more than 95 % of strains were identified to species level. Seven different species were encountered in this study, with Aeromonas caviae being dominant, followed by Aeromonas hydrophila and Aeromonas veronii biovar sobria. Thirty different serotypes were encountered, with O16, O83 and O85 being dominant, but no serotype was associated specifically with a single species. The majority of Aeromonas strains exhibited multidrug resistance. The alt and act genes, which encode heat-labile cytotonic and cytotoxic enterotoxins, were respectively found in 71.9 and 20.1 % of strains examined. Only 2.4 % of strains carried the heat-stable cytotonic enterotoxin (ast) gene. The hlyA gene was found in 28 % of Aeromonas strains. With few exceptions, genomic diversity of Aeromonas strains belonging to the same serotype was observed by random amplification of polymorphic DNA PCR and ribotyping. Different species of Aeromonas and different clones of Aeromonas species seem to be associated with hospitalized cases of diarrhoea in Kolkata, India.

115 citations

Journal ArticleDOI
TL;DR: The results suggest that an integrated approach to environmental interventions can have a significant impact on diarrhoeal morbidity in children under 5 years old in Bangladesh.
Abstract: The impact of a water, sanitation and hygiene education intervention project on diarrhoeal morbidity in children under 5 years old was evaluated in a rural area of Bangladesh. Data were collected throughout 1984-1987, covering both pre- and post-intervention periods, from an intervention and a control area. The 2 areas were similar with respect to most socio-economic characteristics and baseline levels of diarrhoeal morbidity. The project showed a striking impact on the incidence of all cases of diarrhoea, including dysentery and persistent diarrhoea. By the end of the study period, children in the intervention area were experiencing 25% fewer episodes of diarrhoea than those in the control area. This impact was evident throughout the year, but particularly in the monsoon season, and in all age groups except those less than 6 months old. Within the intervention area, children from households living closer to handpumps or where better sanitation habits were practised experienced lower rates of diarrhoea. These results suggest that an integrated approach to environmental interventions can have a significant impact on diarrhoeal morbidity.

115 citations

Journal ArticleDOI
TL;DR: Colostrum from cows immunized with rotavirus antigen is clinically effective in reducing the duration and severity of childhood diarrhoea due to rotav virus.
Abstract: The therapeutic efficacy of hyperimmune bovine colostrum (HBC) from cows immunized with four serotypes of human rotavirus was evaluated in a double-blind, randomized trial in 75 boys, aged 6-24 months, infected with rotavirus diarrhoea. The treatment group received 100 ml of HBC three times a day for 3 consecutive days, while the controls received the same amount of bovine colostrum from significantly shorter duration of diarrhoea than the controls (median 56 versus 72 h (p<0.001); confidence interval of median difference (CI) 8-32 h). Total stool output (g/kg) between admission and cessation of diarrhoea was reduced by 29% in the HBC-treated group compared with controls (median 205 versus 290 g (p=0.04); CI = 1-154 g). In 50% of the children in the study group, diarrhoea stopped by 48 h, whereas 100% of the controls were still suffering from diarrhoea. No untoward effects were noted in either group. Colostrum from cows immunized with rotavirus antigen is clinically effective in reducing the duration and severity of childhood diarrhoea due to rotavirus.

114 citations


Authors

Showing all 3121 results

NameH-indexPapersCitations
Stanley Falkow13434962461
Myron M. Levine12378960865
Roger I. Glass11647449151
Robert F. Breiman10547343927
Harry B. Greenberg10043334941
Barbara J. Stoll10039042107
Andrew M. Prentice9955046628
Robert H. Gilman9690343750
Robert E. Black9220156887
Johan Ärnlöv9138690490
Juan Jesus Carrero8952266970
John D. Clemens8950628981
William A. Petri8550726906
Toshifumi Hibi8280828674
David A. Sack8043723320
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20235
202234
2021494
2020414
2019391
2018334