Istituto Italiano di Tecnologia

About: Istituto Italiano di Tecnologia is a facility organization based out in Genoa, Italy. It is known for research contribution in the topics: Humanoid robot & Robot. The organization has 4561 authors who have published 14595 publications receiving 437558 citations. The organization is also known as: Italian Institute of Technology & IIT.

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

Abstract: Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

A High-performance Redundantly Actuated Parallel Mechanism for Ankle Rehabilitation

Abstract: In this paper we present a redundantly actuated parallel mechanism for ankle rehabilitation. The proposed device has the advantage of mechanical and kinematic simplicity when compared with the state-of-the-art multi-degree-of-freedom parallel mechanism prototypes while at the same time it is fully capable of carrying out the exercises required by the ankle rehabilitation protocols. Optimization of the device workspace, dexterity, torque output and size was carried out during the design phase of the device. The development of the system involved the realization of a new customized linear actuator able to meet the speed and force requirements of the device functionality. We also discuss the impedance-based control scheme used for the redundantly actuated device, which allows the execution of both assistive and resistive strengthening rehabilitation regimes. Results from the control of a single linear actuator and further experimental tests including the position tracking of the fully actuated platform are presented. It is believed that the performance and the simplicity of the proposed mechanism will allow the widespread use of the system as a new aid tool for ankle rehabilitation.

Toward Dexterous Manipulation With Augmented Adaptive Synergies: The Pisa/IIT SoftHand 2

Abstract: In recent years, a clear trend toward simplification emerged in the development of robotic hands. The use of soft robotic approaches has been a useful tool in this prospective, enabling complexity reduction by embodying part of grasping intelligence in the hand mechanical structure. Several hand prototypes designed according to such principles have accomplished good results in terms of grasping simplicity, robustness, and reliability. Among them, the Pisa/IIT SoftHand demonstrated the feasibility of a large variety of grasping tasks, by means of only one actuator and an opportunely designed tendon-driven differential mechanism. However, the use of a single degree of actuation prevents the execution of more complex tasks, like fine preshaping of fingers and in-hand manipulation. While possible in theory, simply doubling the Pisa/IIT SoftHand actuation system has several disadvantages, e.g., in terms of space and mechanical complexity. To overcome these limitations, we propose a novel design framework for tendon-driven mechanisms, in which the main idea is to turn transmission friction from a disturbance into a design tool. In this way, the degrees of actuation (DoAs) can be doubled with little additional complexity. By leveraging on this idea, we design a novel robotic hand, the Pisa/IIT SoftHand 2. We present here its design, modeling, control, and experimental validation. The hand demonstrates that by opportunely combining only two DoAs with hand softness, a large variety of grasping and manipulation tasks can be performed, only relying on the intelligence embodied in the mechanism. Examples include rotating objects with different shapes, opening a jar, and pouring coffee from a glass.