Istituto Italiano di Tecnologia

About: Istituto Italiano di Tecnologia is a facility organization based out in Genoa, Italy. It is known for research contribution in the topics: Robot & Humanoid robot. The organization has 4561 authors who have published 14595 publications receiving 437558 citations. The organization is also known as: Italian Institute of Technology & IIT.

Broadband, electrically tunable third-harmonic generation in graphene

Abstract: Optical harmonic generation occurs when high intensity light (>1010 W m–2) interacts with a nonlinear material. Electrical control of the nonlinear optical response enables applications such as gate-tunable switches and frequency converters. Graphene displays exceptionally strong light–matter interaction and electrically and broadband tunable third-order nonlinear susceptibility. Here, we show that the third-harmonic generation efficiency in graphene can be increased by almost two orders of magnitude by controlling the Fermi energy and the incident photon energy. This enhancement is due to logarithmic resonances in the imaginary part of the nonlinear conductivity arising from resonant multiphoton transitions. Thanks to the linear dispersion of the massless Dirac fermions, gate controllable third-harmonic enhancement can be achieved over an ultrabroad bandwidth, paving the way for electrically tunable broadband frequency converters for applications in optical communications and signal processing. Gate tunable and ultrabroadband third-harmonic generation can be achieved in graphene, paving the way for electrically tunable broadband frequency converters for applications in optical communications and signal processing.

Plug-and-Play CNN for Crowd Motion Analysis: An Application in Abnormal Event Detection

Abstract: Most of the crowd abnormal event detection methods rely on complex hand-crafted features to represent the crowd motion and appearance. Convolutional Neural Networks (CNN) have shown to be a powerful instrument with excellent representational capacities, which can leverage the need for hand-crafted features. In this paper, we show that keeping track of the changes in the CNN feature across time can be used to effectively detect local anomalies. Specifically, we propose to measure local abnormality by combining semantic information (inherited from existing CNN models) with low-level optical-flow. One of the advantages of this method is that it can be used without the fine-tuning phase. The proposed method is validated on challenging abnormality detection datasets and the results show the superiority of our approach compared with the state-of-theart methods.

TMEM16B induces chloride currents activated by calcium in mammalian cells.

Abstract: Ca(2+)-activated Cl(-) channels play important physiological roles in various cell types, but their molecular identity is still unclear. Recently, members of the protein family named transmembrane 16 (TMEM16) have been suggested to function as Ca(2+)-activated Cl(-) channels. Here, we report the functional properties of mouse TMEM16B (mTMEM16B) expressed in human embryonic kidney (HEK) 293T cells, measured both in the whole-cell configuration and in inside-out excised patches. In whole cell, a current induced by mTMEM16B was activated by intracellular Ca(2+) diffusing from the patch pipette, released from intracellular stores through activation of a G-protein-coupled receptor, or photoreleased from caged Ca(2+) inside the cell. In inside-out membrane patches, a current was rapidly activated by bath application of controlled Ca(2+) concentrations, indicating that mTMEM16B is directly gated by Ca(2+). Both in the whole-cell and in the inside-out configurations, the Ca(2+)-induced current was anion selective, blocked by the Cl(-) channel blocker niflumic acid, and displayed a Ca(2+)-dependent rectification. In inside-out patches, Ca(2+) concentration for half-maximal current activation decreased from 4.9 microM at -50 mV to 3.3 microM at +50 mV, while the Hill coefficient was >2. In inside-out patches, currents showed a reversible current decrease at -50 mV in the presence of a constant high Ca(2+) concentration and, moreover, an irreversible rundown, not observed in whole-cell recordings, indicating that some unknown modulator was lost upon patch excision. Our results demonstrate that mTMEM16B functions as a Ca(2+)-activated Cl(-) channel when expressed in HEK 293T cells.

A novel actuator with adjustable stiffness (AwAS)

Abstract: This paper describes the design and development of a new actuator with adjustable stiffness (AwAS) which can be used in robots which are necessary to work close to or physically interact with humans, e.g. humanoids and exoskeletons. The actuator presented in this work can independently control equilibrium position and stiffness by two motors. The first motor controls the equilibrium position while the second motor regulates the compliance. The novelty of the proposed design with respect to the existing systems is on the principle used to regulate the compliance. This is done not through the tuning of the pretension of the elastic element as in the majority of existing system but by controlling the fixation of the elastic elements (springs) using a linear drive. An important consequence of this approach is that the displacement needed to change the stiffness is perpendicular to the forces generated by the springs, thus this helps to minimize the energy/power required to change the stiffness. This permits the use of a small motor for the stiffness adjustment resulting in a lighter setup. Experimental results are presented to show the ability of AwAS to control position and regulate the stiffness independently.