Institution
Jadavpur University
Education•Kolkata, India•
About: Jadavpur University is a education organization based out in Kolkata, India. It is known for research contribution in the topics: Population & Fuzzy logic. The organization has 10856 authors who have published 27678 publications receiving 422069 citations. The organization is also known as: JU & Jadabpur University.
Papers published on a yearly basis
Papers
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TL;DR: This review's main objective is to explore the capability to specifically manipulate MT levels in cells and in animals to provide answers regarding how MT could impact those complex disease scenarios.
Abstract: The Metallothionein (MT) is a protein which has several interesting biological effects and has been demonstrated increase focus on the role of MT in various biological systems in the past three decades. The studies on the role of MT were limited with few areas like apoptosis and antioxidants in selected organs even fifty years after its discovery. Now acknowledge the exploration of various isoforms of MT such as MT-I, MT-II, MT-III and MT-IV and other isoforms in various biological systems. Strong evidence exists that MT modulates complex diseases and the immune system in the body but the primary function of MT still remains unknown. This review's main objective is to explore the capability to specifically manipulate MT levels in cells and in animals to provide answers regarding how MT could impact those complex disease scenarios. The experimental result mentioned in this review related among MT, zinc, cadmium, diabetic, heart disease, bone retardation, neuro toxicity, kidney dysfunction, cancer, and brain suggest novel method for exploration and contribute significantly to the growing scientist to research further in this field.
216 citations
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TL;DR: The results indicate that MECB exhibited significant antitumor and antioxidant activity in EAC-bearing mice.
216 citations
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TL;DR: In this article, the authors have successfully fabricated hybrid nanocomposite film consisting of chitosan, gelatin, polyethylene glycol and silver nanoparticles (AgNPs) by solution casting method.
216 citations
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TL;DR: The Mesoproterozoic Sausar Mobile Belt (SMB), the Chhotanagpur Granite Gneiss Complex (CGGC), and the gneissic complex of Northeast India represent the wider southern belt.
215 citations
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TL;DR: In vitro acetylcholinesterase inhibitory activity is tested based on Ellman's method in 96‐well microplates using AChE obtained from bovine erythrocytes using herbs used in Indian systems of medicine in an attempt to reduce the cognitive decline caused by cholinergic deficits.
Abstract: The cholinergic hypothesis of Alzheimer's disease (AD) has provided the rationale for the current pharmaco-therapy of this disease, in an attempt to reduce the cognitive decline caused by cholinergic deficits. Nevertheless, the search for potent and long-acting acetylcholinesterase (AChE) inhibitors that exert minimal side effects in AD patients is still ongoing. AChE inhibitors are currently the only approved therapy for the treatment of Alzheimer's disease; only a limited number of drugs are commercially available. Hydroalcohol extracts of six herbs, Andrographis paniculata, Centella asiatica, Evalvulus alsinoides, Nardostachys jatamansi, Nelumbo nucifera, Myristica fragrans used in Indian systems of medicine, were tested for in vitro acetylcholinesterase inhibitory activity based on Ellman's method in 96-well microplates using AChE obtained from bovine erythrocytes. The results showed that the hydroalcohol extract from Centella asiatica, Nardostachys jatamansi, Myristica fragrans, Evalvulus alsinoides inhibited 50% of AChE activity at concentrations of 100-150 microg/mL. Andrographis paniculata and Nelumbo nucifera extracts showed a weak inhibition of acetylcholinesterase with IC(50) values of 222.41 +/- 19.87 microg/mL and 185.55 +/- 21.24 microg/mL, respectively. Physostigmine was used as a standard and showed inhibition of acetylcholinesterase with an IC(50) value of 0.076 +/- 0.0042 microg/mL.
214 citations
Authors
Showing all 10999 results
Name | H-index | Papers | Citations |
---|---|---|---|
Subir Sarkar | 149 | 1542 | 144614 |
Amartya Sen | 149 | 689 | 141907 |
Susumu Kitagawa | 125 | 809 | 69594 |
Praveen Kumar | 88 | 1339 | 35718 |
Rodolphe Clérac | 78 | 506 | 22604 |
Rajesh Gupta | 78 | 936 | 24158 |
Santanu Bhattacharya | 67 | 400 | 14039 |
Swagatam Das | 64 | 370 | 19153 |
Anupam Bishayee | 62 | 237 | 11589 |
Michael G. B. Drew | 61 | 1315 | 24747 |
Soujanya Poria | 57 | 175 | 13352 |
Madeleine Helliwell | 54 | 370 | 9898 |
Tapas Kumar Maji | 54 | 253 | 9804 |
Pulok K. Mukherjee | 54 | 296 | 10873 |
Dipankar Chakraborti | 54 | 115 | 12078 |