Jadavpur University

About: Jadavpur University is a education organization based out in Kolkata, India. It is known for research contribution in the topics: Population & Schiff base. The organization has 10856 authors who have published 27678 publications receiving 422069 citations. The organization is also known as: JU & Jadabpur University.

Particle swarm optimization technique based short-term hydrothermal scheduling

Abstract: Particle swarm optimization is applied to determine the optimal hourly schedule of power generation in a hydrothermal power system. A multi-reservoir cascaded hydroelectric system with a nonlinear relationship between water discharge rate, net head and power generation is considered. The water transport delay between connected reservoirs is taken into account. In the present work, the effects of valve point loading in the fuel cost function of the thermal plants are also taken into consideration. The developed algorithm is illustrated for a test system consisting of four hydro plants and three thermal plants. Cost characteristics of individual thermal units are considered. The test results are compared with those obtained using evolutionary programming and simulated annealing technique. It is found that the convergence characteristic is excellent and the results obtained by the proposed method are superior in terms of fuel cost and computation time.

N6-methyladenosine modification in mRNA: machinery, function and implications for health and diseases.

Abstract: N6-methyladenosine (m(6) A) modification in mRNA is extremely widespread, and functionally modulates the eukaryotic transcriptome to influence mRNA splicing, export, localization, translation, and stability. Methylated adenines are present in a large subset of mRNAs and long noncoding RNAs (lncRNAs). Methylation is reversible, and this is accomplished by the orchestrated action of highly conserved methyltransferase (m(6) A writer) and demethylase (m(6) A eraser) enzymes to shape the cellular 'epitranscriptome'. The engraved 'methyl code' is subsequently decoded and executed by a group of m(6) A reader/effector components, which, in turn, govern the fate of the modified transcripts, thereby dictating their potential for translation. Reversible mRNA methylation thus adds another layer of regulation at the post-transcriptional level in the gene expression programme of eukaryotes that finely sculpts a highly dynamic proteome in order to respond to diverse cues during cellular differentiation, immune tolerance, and neuronal signalling.