Jadavpur University

About: Jadavpur University is a education organization based out in Kolkata, India. It is known for research contribution in the topics: Population & Fuzzy logic. The organization has 10856 authors who have published 27678 publications receiving 422069 citations. The organization is also known as: JU & Jadabpur University.

An improved auto-tuning scheme for PI controllers.

Abstract: Ziegler-Nichols tuned PI and PID controllers are usually found to provide poor performances for high-order and nonlinear systems. In this study, an improved auto-tuning scheme is presented for Ziegler-Nichols tuned PI controllers (ZNPICs). With a view to improving the transient response, the proportional and integral gains of the proposed controller are continuously modified based on the current process trend. The proposed controller is tested for a number of high-order linear and nonlinear dead-time processes under both set-point change and load disturbance. It exhibits significantly improved performance compared to ZNPIC, and Refined Ziegler-Nichols tuned PI controller (RZNPIC). Robustness of the proposed scheme is established by varying the controller parameters as well as the dead-time of the process under control.

Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.

Abstract: Adaptogens comprise a category of herbal medicinal and nutritional products promoting adaptability, resilience, and survival of living organisms in stress. The aim of this review was to summarize the growing knowledge about common adaptogenic plants used in various traditional medical systems (TMS) and conventional medicine and to provide a modern rationale for their use in the treatment of stress-induced and aging-related disorders. Adaptogens have pharmacologically pleiotropic effects on the neuroendocrine-immune system, which explain their traditional use for the treatment of a wide range of conditions. They exhibit a biphasic dose-effect response: at low doses they function as mild stress-mimetics, which activate the adaptive stress-response signaling pathways to cope with severe stress. That is in line with their traditional use for preventing premature aging and to maintain good health and vitality. However, the potential of adaptogens remains poorly explored. Treatment of stress and aging-related diseases require novel approaches. Some combinations of adaptogenic plants provide unique effects due to their synergistic interactions in organisms not obtainable by any ingredient independently. Further progress in this field needs to focus on discovering new combinations of adaptogens based on traditional medical concepts. Robust and rigorous approaches including network pharmacology and systems pharmacology could help in analyzing potential synergistic effects and, more broadly, future uses of adaptogens. In conclusion, the evolution of the adaptogenic concept has led back to basics of TMS and a new level of understanding of holistic approach. It provides a rationale for their use in stress-induced and aging-related diseases.