Showing papers by "Jagiellonian University published in 1988"
TL;DR: Melanin altered these reactions by several different mechanisms and consequently, depending on conditions, can significantly increase or decrease the yield of reactive products, including hydroxyl radicals.
130 citations
TL;DR: The elastolytic activity of this S. aureus proteinase and its lack of control by human kininogens or cystatin C may explain some of the connective tissue destruction seen in bacterial infections due to this and related organisms such as may occur in septicemia, septic arthritis, and otitis.
113 citations
TL;DR: In this paper, the properties of the OH groups in NaHZSM-5 zeolite absorbing at 3609 cm −1 were studied with respect to their hydrogen bonding to weak electron donor molecules.
99 citations
TL;DR: The semi-empirical Atoms-in-a-Molecule (AIM) hardness matrix, η, is defined, using the usual finite difference formula, i = Ii-Ai, for the diagonal AIM hardness and the Ohno formula, ǫ = 1/(a2 + R)1/2, for off-diagonal AI hardness.
Abstract: The semiempirical Atoms-in-a-Molecule (AIM) hardness matrix, η, is defined, using the usual finite difference formula, ηii = Ii – Ai, for the diagonal AIM hardness and the Ohno formula, ηij = 1/(a2 + R)1/2, for the off-diagonal AIM hardness. The Ohno formula is shown to exhibit the correct asymptotic behavior and satisfies the relevant stability criterion. The normal displacements in the AIM electron populations are examined for pyrrole and N-methyl pyrrole, and their relation to the polarization channels is briefly discussed. The new AIM hardness matrix is also tested by comparing the predicted global hardnesses with the corresponding experimental finite difference data for selected diatomics and triatomics. Finally implications of the hardness combination rules are examined and the corresponding softness combination rules are used to calculate the regional and global softnesses of selected molecules. We examine how the regional softnesses reflect known trends in selectivity of protonation of five membered heterocycles, and comment on the signs of the AIM fukui function and the Hard-Soft-Acids-and-Bases principle.
88 citations
TL;DR: Astrocyte response to unilateral injury of the cerebral hemisphere in newborn rats was studied both autoradiographically and immunocytochemically to establish evidence of reactive astrocyte proliferation in the rat brain injured at birth.
81 citations
TL;DR: A naturally occurring plasma serine proteinase inhibitor can have multiple specificities through interactions at adjacent sites, and this work illustrates the potential flexibility of the reactive site loop in this class of inhibitors.
Abstract: Although the proteinase inhibitor alpha-2-antiplasmin (alpha 2AP) is known to control the activity of plasmin through rapid formation of stable complexes, it also efficiently inactivates chymotrypsin. These interactions are shown to occur at adjacent, overlapping sites so that plasmin attacks the inhibitor at an Arg364-Met365 peptide bond, while chymotrypsin interacts at a Met365-Ser366 sequence one residue downstream. Thus, a naturally occurring plasma serine proteinase inhibitor can have multiple specificities through interactions at adjacent sites. It also illustrates the potential flexibility of the reactive site loop in this class of inhibitors.
67 citations
TL;DR: Tadpoles of the fire-bellied toad reared in the laboratory in a high density of siblings grew better and developed faster than when they were reared with similar densities of nonrelatives, and had a much larger absolute body weight than the smallest tadpoles from mixed-sibship cohorts.
Abstract: This study provides an experimental test of the ecological significance of kinship in competitive interactions among individuals. Tadpoles of the fire-bellied toad, Bombina variegata (Anura, Discoglossidae) reared in the laboratory in a high density of siblings grew better and developed faster than when they were reared with similar densities of nonrelatives. Kinship-based genotypic uniformity may therefore be advantageous: it can lead to faster and more uniform growth. In nature it may well be kin recognition that permits such advantage to be realised. The largest tadpoles from pure-sibship cohorts accounted, on average, for the smaller fraction of the cohort total biomass than the largest tadpoles reared with cohorts of nonrelatives, although they attained the same absolute weight and developmental stage. The smallest individuals from pure-sibship cohorts had a much larger absolute body weight than the smallest tadpoles from mixed-sibship cohorts, and were also much more advanced developmentally. The results could be an effect of an altruistic restraint in growth rate on the part of the largest tadpoles in sibling cohorts and certainly not of the smallest ones. However, the results could also be due to the altruism-independent facilitation of living conditions in pure-sibship groups, resulting solely from potential advantages of homogeneous water conditioning.
49 citations
TL;DR: It is concluded that measurement of stomata length is a rapid technique for identifying ploidy level in kiwifruit.
Abstract: The suitability of stomatal length as a criterion in the distinction between haploid (2n=85) and diploid (2n=170) plants of Actinidia deliciosa (A. Chev.) C.-F. Liang et A.R. Ferguson (kiwifruit); was tested. Seedlings and mature plants for this study were grown in a glasshouse. Mean stomatal lengths were 26.4±2.4 μm for haploids and 37.9±3.8 μm for diploids in the seedlings, and 24±1.7 μm and 33±2.4 μm, respectively, in mature plants. The means from haploid plants did not overlap with the means from diploid plants (significance at less than 0.001%) in 374 plants evaluated. It is concluded that measurement of stomata length is a rapid technique for identifying ploidy level in kiwifruit.
48 citations
TL;DR: Comparison of the amino acid sequence at or near the reactive site of the horse inhibitor (P2-P18') with members of the serpin superfamily of proteinase inhibitors indicates that it not only belongs in this class but also represents the first example of a functionally active intracellular serpin.
46 citations
45 citations
TL;DR: In this paper, it was shown that plastoquinone (PQ) and α-tocopherol quinone (α-TQ) can form quinhydrone-type charge transfer complexes on PQH2 and TQH 2, respectively, both in the crystalline state and in solutions of organic solvents.
TL;DR: The method was used to decompose emission fluorescence spectra in two-tryptophan-containing proteins; horse liver dehydrogenase, sperm whale apomyoglobin and metalloprotease from Staphylococcus aureus and is technically simple and does not require expensive instrumentation.
Abstract: A new procedure is described for using fluorescence-quenching data of tryptophan residues in proteins to resolve their fluorescence emission spectra. In this concept the Stern-Volmer quenching plot is determined at each particular emission wavelength and itterative non-linear least-squares fitting procedure allowed to resolve the steady-state emission spectra into components. The resolved components, attributed to each of tryptophan residue, can be characterized by different accessibility to the quencher. The ability to resolve fluorescence emission spectra can be improved by using different kinds of efficient quenchers, which can selectively quench the emission of exposed or both exposed and buried fluorophores. The method was used to decompose emission fluorescence spectra in two-tryptophan-containing proteins; horse liver dehydrogenase, sperm whale apomyoglobin and metalloprotease from Staphylococcus aureus. The resolved spectra of alcohol dehydrogenase and metalloprotease are in excellent agreement with those previously obtained by single-photon counting or phase methods. The method presented here is technically simple and does not require expensive instrumentation.
TL;DR: An algorithm is provided to determine the age at which energy allocation to reproduction should start, and theAge at which vegetative growth should cease altogether, and in the case of a gradual switch, the seed yield is only slightly lower then it would have been if an instantaneous switch-over had been possible.
TL;DR: Using pulse radiolysis and electron spin resonance spectroscopy, the rates of reaction of various ortho-semiquinones with molecular oxygen are measured and it is shown that catechol(amine)s which form noncyclizable quinones are more cytotoxic toward melanogenic cells than those forming cyclizableQuinones.
TL;DR: The notions introduced in the paper are useful for researches in less restricted edNLC-graph Grammars, for example grammars analogical to context-free string grammARS.
Journal Article•
TL;DR: It is concluded that the cascades of inflammatory cytokines in different tissues represent amplification and regulatory pathways controlling the development of acute phase response in vivo.
Abstract: The acute phase cytokines: interleukin 1, tumor necrosis factor alpha (cachectin) and beta (lymphotoxin), hepatocyte stimulating factor and several interferons, all belong to the family of endotoxin-inducible, low molecular weight proteins. Their synthesis in macrophages, fibroblasts, lymphocytes, epithelial and some tumor cells is enhanced by the same cytokines, often in the autocrine manner, and suppressed by dexamethasone. The principal hepatocyte stimulating factor (HSF) regulating synthesis of acute phase proteins is probably identical with IFN-beta 2/BSF-2/IL-6, but other inflammatory cytokines (IL-1, TNF alpha, IFN-gamma) are able to induce distinct sets of acute phase proteins, or to modulate the final response pattern. The effect of hrIFN-gamma on production of acute phase proteins by human hepatoma Hep G2 cells is discussed in detail. It is concluded that the cascades of inflammatory cytokines in different tissues represent amplification and regulatory pathways controlling the development of acute phase response in vivo.
TL;DR: In this paper, the authors investigated the catalytic performance of benzene over V2O5, V6O13 and V4O7 at 300-400 °C and showed that the selectivity with respect to maleic anhydride in the case of pure oxides was generally low.
TL;DR: A high MP concentration decreases the production of Ig in culture after stimulation with PWM whereas lower concentrations of MP enhance this production, and the possible action of exoproteinase from S. Aureus on the immune response during infection is discussed.
TL;DR: In this paper, the solvent-dependent absorption bands at low energy assigned to W→bpy transitions were characterized by u.v. and visible, i.r. spectrometry, t.s. and d.t. analysis.
Abstract: (bpyH)3(H3O)[W(CN)8]·H2O reacts at high temperature to give the ionic species [W(bpy)(CN)6]2−. Tetraphenylphosphonium and tetraphenylarsonium salts were isolated as solids whereas the acid and its alkali metal salts were investigated in solution. The new complexes were characterized by u.v. and visible, i.r. and e.s.r. spectrometry, t.g. and d.t. analysis. The intensively coloured salts exhibit solvent—dependent absorption bands at low energy assigned to W→bpy transitions.
TL;DR: In this article, the reliability of self-ratings based on the Borg's scale in the assessment of hand-arm vibrations of short duration was investigated and it was shown that the reliability coefficients are statistically significant (p ⩽ 0.05) and high: 0.986 for experienced subjects and 0.841 for inexperienced subjects.
TL;DR: In this paper, an analysis of the orientation spatiale of 118 galaxies avec mp≤14,0 dans le superamas de Persee montre que les axes de rotation des galaxies ont tendance a etre alignes avec le plan du superamas.
Abstract: L'analyse de l'orientation spatiale de 118 galaxies avec mp≤14,0 dans le superamas de Persee montre que les axes de rotation des galaxies ont tendance a etre alignes avec le plan du superamas
TL;DR: A model is proposed that provides an explanation in terms of evolutionary ecology for why males copulate with unisexuals, and assumes that, before copulation, a male attempts to identify a female as conspecific or not but that the correctness of the identification depends on the length of time spent on the identification process.
Abstract: Unisexual poeciliid fishes live as sexual parasites in breeding complexes with related bisexual species. Males of the host species copulate with unisexual females as well as with con-specifics, thus maintaining the unisexuals. Copulation with a unisexual offers no selective benefit for a male. A model is proposed that provides an explanation in terms of evolutionary ecology for why males copulate with unisexuals. It assumes that, before copulation, a male attempts to identify a female as conspecific or not but that the correctness of the identification depends on the length of time spent on the identification process. Some cost is involved in the passage of time, so an optimal time spent on identification must exist. Because subordinate males risk being driven away by dominant males, the optimal time is longer for males at the top of the dominance hierarchy than for males at the bottom. Such an optimal strategy gives a male the greatest possible average net benefit from a mating attempt, given his social status; this is a "best of a bad job" strategy.
TL;DR: In this paper, acid and catalytic properties of H,NaZSM-5 (Si/Al = 47) zeolites of various exchange degrees (0−98%) were studied.
TL;DR: The genetical effects of kinship and the ecological effects of age structure were shown to affect the interactions of Tribolium larvae reared in groups, reducing the similarity between individuals, either genetically or demographically, changed the pattern of larval interactions.
Abstract: The larvae of flour beetles Tribolium castaneum and T. confusum were reared in two kinds of groups: full siblings and unrelated individuats. These kin and nonkin groups were reared in open cultures, in which emigration was permitted (both species) and in closed cultures, in which emigration was prohibited (only T. confusum). We measured larval development time and survivorship, weight of pupae, and time of larval emigration from open cultures. The effects of age structure were investigated by establishing open cultures of larvae of uniform age (larvae hatched from eggs laid within 72 h) and cultures of larvae of variable age (eggs laid within 240 h). In closed cultures of siblings, T. confusum larvae pupated on an average 2.2 days earlier than larvae reared in nonsibling groups. In T. castaneum, more small and medium size and fewer large size larvae emigrated from groups of siblings compared to groups of nonsiblings. Males that emigrated and pupated remained with their sibs for a shorter time than did similar males raised with unrelated larvae. In T. castaneum, age structure variation reduced the sibs tendency to migrate, but did not influence interactions among unrelated larvae. The genetical effects of kinship and the ecological effects of age structure were shown to affect the interactions of Tribolium larvae reared in groups. Reducing the similarity between individuals, either genetically or demographically (using mixed broods or mixed age cohorts), changed the pattern of larval interactions. Upon occasion, the effects of kin interactions may well be the mechanical consequences of the coexistence of similar individuals rather than the effects of altruistic behavior.
TL;DR: Severe depletion of plasma level of proteinase inhibitors, and especially of α2-macroglobulin / α2M/, has a bad prognostic significance, however, the acute phase response usually facilitates replenishment ofproteinase inhibitors due to their enhanced liver synthesis.
Abstract: A dynamic equilibrium between the blood or tissue proteinases and their inhibitors is drastically disturbed during acute inflammation elicited by various noxious stimuli /Fritz, 1980; Koj 1985b; Fritz et al., 1986/. A massive release of proteolytic enzymes from injured cells and from infiltrating leucocytes and macrophages must be promptly neutralized by a range of antiproteases present in body fluids /Fig.1/. Since the reaction between proteinases and inhibitors is in most cases irreversible and resulting complexes are quickly removed the enhanced proteolytic activity could seriously deplete the body reserves of these antiproteases. As demonstrated by the elegant studies of Ohlsson / 1974 / and Fritz and co-workers /198O, 1986/ such situations occur in certain cases of acute pancreatitis and septic shock or endotoxaemia. Severe depletion of plasma level of proteinase inhibitors, and especially of α2-macroglobulin / α2M/, has a bad prognostic significance. However, the acute phase response usually facilitates replenishment of proteinase inhibitors due to their enhanced liver synthesis.
TL;DR: In this paper, seven local biostratigraphic zones have been distinguished in the Albian and Cenomanian sediments of the Pieniny Klippen Belt: Hedbergella assemblage (Assemblage Zone, AZ), R. ticinensis- P. buxtorfi- R. appenninica (CRZ).
TL;DR: On caracterise les varietes des algebres de Heyting avec la theorie decidable de leurs membres finis d'augmentation de l’homme d’un système généralement difficile.
Abstract: The aim of this paper is to characterize varieties of Heyting algebras with decidable theory of their finite members. Actually we prove that such varieties are exactly the varieties generated by linearly ordered algebras. It contrasts to the result of Burris [2] saying that in the case of whole varieties, only trivial variety and the variety of Boolean algebras have decidable first order theories.
TL;DR: In this paper, a procedure for the characterization of iron catalysts is proposed for ammonia synthesis in unreduced form, in which the content of major and minor cations, including Fe2+, and the total amount of iron are established.
TL;DR: In this article, the concentrations of Bronsted and Lewis acid sites were determined in NaHZSM-5 zeolites of various Si/AI ratios and in Na HZSM11.
TL;DR: In this article, a study was conducted to determine whether mental fatigue connected with high and low stimulation at work can affect the subjects' perception of pain, and the results showed that mental fatigue due to a high level of stimulation caused an increase in pain ratings, while the mental fatigue caused by low stimulation level caused a decrease in pain rating.
Abstract: The object of this study was to determine whether mental fatigue connected with high and low stimulation at work can affect the subjects' perception of pain. Two groups of female visual display unit operators were studied: the first group performed tasks involving high levels of stimulation, while the second group performed tasks involving low levels of stimulation. The results show that mental fatigue due to a high level of stimulation causes an increase in pain ratings, while the mental fatigue due to low stimulation level causes a decrease in pain ratings.