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Institution

James Cook University

EducationTownsville, Queensland, Australia
About: James Cook University is a education organization based out in Townsville, Queensland, Australia. It is known for research contribution in the topics: Population & Coral reef. The organization has 9101 authors who have published 27750 publications receiving 1032608 citations. The organization is also known as: JCU.
Topics: Population, Coral reef, Reef, Coral, Coral reef fish


Papers
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Journal ArticleDOI
TL;DR: In this paper, an equation for the average daily downward heat flow of a sunlit roof is derived using building simulation, and it is first shown that the thermal mass of the roof does not significantly affect the overall daily heat gain (although it causes a time lag and reduction in peak heat flow).

219 citations

Journal ArticleDOI
TL;DR: The conceptual model proposed here discusses some of the crosslinks between responses at different levels of biological organisation and the central role of oxygen balance and oxidative stress in eliciting these responses with the aim of helping the interpretation of environmental genomic data in the context of organismal function and performance.
Abstract: Recent advances in molecular biology and the use of DNA microarrays for gene expression profiling are providing new insights into the animal stress response, particularly the effects of stress on gene regulation. However, interpretation of the complex transcriptional changes that occur during stress still poses many challenges because the relationship between changes at the transcriptional level and other levels of biological organisation is not well understood. To confront these challenges, a conceptual model linking physiological and transcriptional responses to stress would be helpful. Here, we provide the basis for one such model by synthesising data from organismal, endocrine, cellular, molecular, and genomic studies. We show using available examples from ectothermic vertebrates that reduced oxygen levels and oxidative stress are common to many stress conditions and that the responses to different types of stress, such as environmental, handling and confinement stress, often converge at the challenge of dealing with oxygen imbalance and oxidative stress. As a result, a common set of stress responses exists that is largely independent of the type of stressor applied. These common responses include the repair of DNA and protein damage, cell cycle arrest or apoptosis, changes in cellular metabolism that reflect the transition from a state of cellular growth to one of cellular repair, the release of stress hormones, changes in mitochondrial densities and properties, changes in oxygen transport capacities and changes in cardio-respiratory function. Changes at the transcriptional level recapitulate these common responses, with many stress-responsive genes functioning in cell cycle control, regulation of transcription, protein turnover, metabolism, and cellular repair. These common transcriptional responses to stress appear coordinated by only a limited number of stress-inducible and redox-sensitive transcription factors and signal transduction pathways, such as the immediate early genes c-fos and c-jun, the transcription factors NFκB and HIF-1α, and the JNK and p38 kinase signalling pathways. As an example of environmental stress responses, we present temperature response curves at organismal, cellular and molecular levels. Acclimation and physiological adjustments that can shift the threshold temperatures for the onset of these responses are discussed and include, for example, adjustments of the oxygen delivery system, the heat shock response, cellular repair system, and transcriptome. Ultimately, however, an organism's ability to cope with environmental change is largely determined by its ability to maintain aerobic scope and to prevent loss in performance. These systemic constraints can determine an organism's long-term survival well before cellular and molecular functions are disturbed. The conceptual model we propose here discusses some of the crosslinks between responses at different levels of biological organisation and the central role of oxygen balance and oxidative stress in eliciting these responses with the aim to help the interpretation of environmental genomic data in the context of organismal function and performance.

219 citations

Journal ArticleDOI
TL;DR: Bacterial community profiles of A. millepora at Orpheus Island were consistent in samples collected throughout the year, indicating a stable community despite temporal changes, but DGGE and T-RFLP profiles differed on corals from different reefs.

219 citations

Journal ArticleDOI
TL;DR: Without an integrated approach to mitigating the disease emergence consequences of environmental change, countries’ abilities to achieve SDGs and GHSA targets will be compromised.
Abstract: The United Nations (UN) launched the 2030 Agenda for Sustainable Development to address an ongoing crisis: human pressure leading to unprecedented environmental degradation, climatic change, social inequality, and other negative planet-wide consequences. This crisis stems from a dramatic increase in human appropriation of natural resources to keep pace with rapid population growth, dietary shifts toward higher consumption of animal products, and higher demand for energy (1, 2). There is an increased recognition that Sustainable Development Goals (SDGs) are linked to one another (3, 4), and priorities such as food production, biodiversity conservation, and climate change mitigation cannot be considered in isolation (5⇓⇓–8). Hence, understanding those dynamics is central to achieving the vision of the UN 2030 Agenda. Infectious zoonotic diseases typically emerge as a result of complex interactions between humans and wild and/or domestic animals. Image credit: Pixabay/sasint. But environmental change also has direct human health outcomes via infectious disease emergence, and this link is not customarily integrated into planning for sustainable development. Currently, 65 countries are engaged in the Global Health Security Agenda (GHSA) and are finalizing a strategic plan for the next five years (the GHSA 2024 Roadmap) to better prevent, detect, and respond to infectious disease outbreaks in alignment with SDGs 2 and 3 on food security and human health. Without an integrated approach to mitigating the disease emergence consequences of environmental change, countries’ abilities to achieve SDGs and GHSA targets will be compromised. Emerging infectious diseases (EIDs) such as Ebola, influenza, SARS, MERS, and, most recently, coronavirus (2019-nCoV) cause large-scale mortality and morbidity, disrupt trade and travel networks, and stimulate civil unrest (9). When local emergence leads to regional outbreaks or global pandemics, the economic impacts can be devastating: The SARS outbreak in 2003, the H1N1 pandemic in 2009, and … [↵][1]1To whom correspondence may be addressed. Email: moreno.dimarco{at}uniroma1.it. [1]: #xref-corresp-1-1

219 citations

Journal ArticleDOI
TL;DR: An emerging body of epidemiological and mechanistic evidence is drawn upon to support the hypothesis that shared inflammatory mechanisms may represent a key biological link in this co-morbidity of bipolar depression and diabetes mellitus.

219 citations


Authors

Showing all 9184 results

NameH-indexPapersCitations
Christopher J L Murray209754310329
Hui-Ming Cheng147880111921
Joseph T. Hupp14173182647
Graeme J. Hankey137844143373
Bryan R. Cullen12137150901
Thomas J. Meyer120107868519
William F. Laurance11847056464
Staffan Kjelleberg11442544414
Mike Clarke1131037164328
Gao Qing Lu10854653914
David J. Williams107206062440
Tim J Peters106103747394
Michael E. Goddard10642467681
Ove Hoegh-Guldberg10642563750
John C. Avise10541353088
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202334
2022170
20211,840
20201,737
20191,671
20181,691