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Institution

Jawaharlal Nehru University

EducationNew Delhi, India
About: Jawaharlal Nehru University is a education organization based out in New Delhi, India. It is known for research contribution in the topics: Population & Candida albicans. The organization has 6082 authors who have published 13455 publications receiving 245407 citations. The organization is also known as: JNU.


Papers
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Journal ArticleDOI
12 Jan 2012-PLOS ONE
TL;DR: It was found that an appropriate molar ratio of protein to SDS readily induced amyloid formation in all proteins at a pH below two units of their respective isoelectric points (pI), and electrostatic interactions play a leading role in the induction of amyloids.
Abstract: Sodium dodecyl sulphate (SDS), an anionic surfactant that mimics some characteristics of biological membrane has also been found to induce aggregation in proteins. The present study was carried out on 25 diverse proteins using circular dichroism, fluorescence spectroscopy, dye binding assay and electron microscopy. It was found that an appropriate molar ratio of protein to SDS readily induced amyloid formation in all proteins at a pH below two units of their respective isoelectric points (pI) while no aggregation was observed at a pH above two units of pI. We also observed that electrostatic interactions play a leading role in the induction of amyloid. This study can be used to design or hypothesize a molecule or drug, which may counter act the factor responsible for amyloid formation.

117 citations

Journal ArticleDOI
TL;DR: In this paper, the authors discuss the challenges of forecasting flood forecasting in hydrology and its critical contribution in reducing the cost of reducing the reduction in reduc... and the importance of hydrology due to its critical contributions in reducing costs.
Abstract: Flood forecasting (FF) is one the most challenging and difficult problems in hydrology. However, it is also one of the most important problems in hydrology due to its critical contribution in reduc...

117 citations

Journal ArticleDOI
TL;DR: The authors examined the pattern of regional inequalities in India during 1970-92 and found that interstate inequality is rising in India in almost every sphere of economic activity, particularly in the unorganised industry.
Abstract: In this article we examine the pattern of regional inequalities in India during 1970–92. Trend analysis shows that inter‐state inequality is rising in India in almost every sphere of economic activity, particularly in the unorganised industry.

117 citations

Journal ArticleDOI
TL;DR: It is reported here that cholesterol depletion from macrophage plasma membranes using methyl-beta-cyclodextrin (MbetaCD) results in a significant reduction in the extent of leishmanial infection, and the reduction of the ability of the parasite to infect host macrophages can be reversed upon replenishment of cell membrane cholesterol.

117 citations


Authors

Showing all 6255 results

NameH-indexPapersCitations
Ashok Kumar1515654164086
Rajesh Kumar1494439140830
Sanjay Gupta9990235039
Rakesh Kumar91195939017
Praveen Kumar88133935718
Rajendra Prasad8694529526
Mukesh K. Jain8553927485
Shiv Kumar Sarin8474028368
Gaurav Sharma82124431482
Santosh Kumar80119629391
Dinesh Mohan7928335775
Govindjee7642621800
Dipak K. Das7532717708
Amit Verma7049716162
Manoj Kumar6540816838
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202385
2022314
20211,314
20201,240
20191,066
20181,012