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Institution

Jewish Hospital

HealthcareCincinnati, Ohio, United States
About: Jewish Hospital is a healthcare organization based out in Cincinnati, Ohio, United States. It is known for research contribution in the topics: Antigen & Population. The organization has 3881 authors who have published 3414 publications receiving 123044 citations.


Papers
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Proceedings ArticleDOI
01 Jan 2008
TL;DR: LDCT images and desired maps of regions (lung and the other chest tissues) are described by a joint Markov-Gibbs random field model (MGRF) of independent image signals and interdependent region labels but focus on most accurate model identification.
Abstract: New techniques for more accurate unsupervised segmentation of lung tissues from Low Dose Computed Tomography (LDCT) are proposed. In this paper we describe LDCT images and desired maps of regions (lung and the other chest tissues) by a joint Markov-Gibbs random field model (MGRF) of independent image signals and interdependent region labels but focus on most accurate model identification. To better specify region borders, each empirical distribution of signals is precisely approximated by a Linear Combination of Discrete Gaussians (LCDG) with positive and negative components. We modify a conventional Expectation-Maximization (EM) algorithm to deal with the LCDG and develop a sequential EM-based technique to get an initial LCDG-approximation for the modified EM algorithm. The initial segmentation based on the LCDG-models is then iteratively refined using a MGRF model with analytically estimated potentials. Experiments on real data sets confirm high accuracy of the proposed approach.

29 citations

Journal ArticleDOI
TL;DR: The area of the striatum was not increased in rats treated with typical antipsychotic agents, but the clozapine-associated area reduction may parallel the clinical studies.

29 citations

Journal ArticleDOI
TL;DR: Analysis of untransformed data under a conditional likelihood provides evidence for Mendelian transmission of a major gene with commingling of two distributions and demonstration of familiality warrants continued investigation of the index as an indicator of liability for schizophrenia.
Abstract: The genetic analysis of schizophrenia would be facilitated by identification of a heritable correlate of liability Deviance on an index of Minnesota Multiphasic Personality Inventory (MMPI) signs is associated with the disease phenotype; the familial aggregation and mode of transmission of this continuous psychometric indicator have yet to be established In this paper, we examine the indicator through commingling analysis and segregation analysis with both the mixed and unified models on 65 nuclear families containing 211 normal individuals Evidence for a high degree of familiality is found Analysis of untransformed data under a conditional likelihood provides evidence for Mendelian transmission of a major gene with commingling of two distributions The frequency of the "high index score" allele is 015, with the gene accounting for 31% of the total population variance; such a locus would be relevant to the study of psychopathology as 28% of the population would carry at least one deviant allele When power-transformed scores are used to eliminate skewness, there is evidence for one distribution and it is not possible to distinguish single gene from multifactorial (polygenic or cultural) inheritance While our findings regarding mode of transmission must be interpreted cautiously and confirmation of a single locus requires further study, demonstration of familiality warrants continued investigation of the index as an indicator of liability for schizophrenia

29 citations

Journal ArticleDOI
TL;DR: In subjects with coagulation disorders and oste onecrosis of the hip, provided that anticoagulant therapy is started before irreversible segmental collapse of the head of the femur, osteonecrosis may be arrested or, speculatively, sometimes reversed.
Abstract: Osteonecrosis develops as the end-result of reduced blood flow to the femoral head. We postulate that venous thrombosis leads to increased intraosseus venous pressure, reduced arterial flow and hypoxic bone death. Hypofibrinolysis (reduced ability to lyse thrombi) and thrombophilia (increased tendency to form thrombi) appear to play an important role in osteonecrosis. If coagulation disorders cause osteonecrosis, then anticoagulation might ameliorate osteonecrosis. In subjects with coagulation disorders and osteonecrosis of the hip, provided that anticoagulant therapy is started before irreversible segmental collapse of the head of the femur, osteonecrosis may be arrested or, speculatively, sometimes reversed. This has the potential of preventing femoral head collapse which usually leads to total hip replacement.

29 citations

Journal ArticleDOI
TL;DR: It is revealed that many nurses need to update their knowledge of those practices found to encourage successful breastfeeding, and only seven of 16 questions were answered correctly by more than 50 percent of the nurses surveyed.
Abstract: Most obstetrical nurses subscribe to the "breast is best" theory. This project examined the current knowledge base of a sample of nurses and their practices relating to breastfeeding in three clinical settings. These study findings reveal that many nurses need to update their knowledge of those practices found to encourage successful breastfeeding. Only seven of 16 questions were answered correctly by more than 50 percent of the nurses surveyed. Areas of adequate knowledge included positioning, breastfeeding frequency, infant suckling patterns, and the importance of night feedings. Areas of inadequate knowledge included timing of the baby at the breast, milk production, use of glucose water, and the use of nipple shields.

28 citations


Authors

Showing all 3894 results

NameH-indexPapersCitations
John C. Morris1831441168413
David L. Kaplan1771944146082
Robert H. Purcell13966670366
Nancy J. Cox135778109195
Jennifer S. Haas12884071315
David A. Cheresh12533762252
John W. Kappler12246457541
Philippa Marrack12041654345
Arthur Weiss11738045703
Thomas J. Kipps11474863240
Michael Pollak11466357793
Peter M. Henson11236954246
Roberto Bolli11152844010
William D. Foulkes10868245013
David A. Lynch10871459678
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20232
202217
202148
202038
201944
201828