Jewish Hospital

About: Jewish Hospital is a healthcare organization based out in Cincinnati, Ohio, United States. It is known for research contribution in the topics: Antigen & Population. The organization has 3881 authors who have published 3414 publications receiving 123044 citations.

Sebaceous cell carcinoma of the parotid region: A review of the literature and a case report

Abstract: The literature concerned with sebaceous elements found within salivary glands can be traced from 1931, when benign sebaceous glands were first described in the submaxillary and the parotid glands, through the 1950's and 1960's, when sebaceous gland adenomas were reported, to 1964 when a report of the first sebaceous cell carcinoma arising in a mixed tumor was published. A case of sebaceous cell carcinoma which arose in the region of the parotid, unrelated to skin appendages or to another tumor, is presented. The carcinoma first was irradiated in an attempt to reduce its size but with little effect on the tumor; it then was removed surgically in August 1965. There has been no evidence of recurrence to date.

A Controlled Double-Blind Study of High-Dose Dihydroergotoxine Mesylate (HydergineR) in Mild Dementia

Abstract: In a double-blind study of 41 outpatients aged 55 to 80 years with mild memory impairment, the efficacy of dihydroergotoxine mesylate (DEM, Hydergine) at 6 mg per day, administered orally, was tested during a twelve-week period. Specific etiologies for the amnesic syndrome were ruled out by history, physical examination, and laboratory tests. Subjects with a Hamilton Depression Scale rating above 18, ie, possible pseudodementia, were excluded. Physician rating of memory, employing the Inventory of Psychic and Somatic Complaints in the Elderly (IPSC-E), indicated statistically significant improvement of memory function in DEM treated subjects (N = 22) v those on placebo (N = 19), (F = 3.34; df = 1,39; P less than .04). In contrast, structured testing of recent memory using digit symbol substitution and Zahlenverbindungs test (ZVT) showed improvement in both groups (P less than .001) with no significant intergroup differences (P less than .10). Out results indicate that in cases of mild, though subjectively distressing impairment, DEM at higher dosages may help to enhance short-term memory function.

Adolescent oligomenorrhea (age 14-19) tracks into the third decade of life (age 20-28) and predicts increased cardiovascular risk factors and metabolic syndrome.

Abstract: Objective Assess whether adolescent oligomenorrhea (age 14–19) tracks into young adulthood (age 20–28) and predicts increased cardiometabolic risk factors, metabolic syndrome (MetS), and impaired fasting glucose-type II diabetes mellitus (IFG + T2DM). Materials and methods Prospective study of menstrual cyclicity and its metabolic effects in 865 black and white schoolgirls from age 9 to 19, and 605 of these 865 girls from age 20 to 28. Main findings Patterns of menstrual delays (oligomenorrhea) during ages 14–19 and ages 20–28 were closely related (p Principal conclusions Menstrual patterns track from adolescence to young adulthood, and oligomenorrhea predicts MetS and IFG + T2DM. Patterns of menses delays in adolescence should be considered as a significant risk factor for future development of young adult IFG + T2DM, MetS, oligomenorrhea, and polycystic ovary syndrome.