Jewish Hospital

About: Jewish Hospital is a healthcare organization based out in Cincinnati, Ohio, United States. It is known for research contribution in the topics: Antigen & Population. The organization has 3881 authors who have published 3414 publications receiving 123044 citations.

The complexometric titration of micro and ultramicro quantities of calcium in blood serum, urine, and inorganic salt solutions.

Abstract: A method for the microdetermination and ultramicrodetermination of calcium in blood serum, urine, and inorganic salt solutions has been developed. Calcium was titrated with disodium ethylenediaminetetraacetate, and Cal-red as the indicator, using a Gilmont ultramicro-buret of 0.1-ml. capacity. Amounts of 5 to 30 µg. of calcium per sample, of 0.05- to 1-ml. volumes, can be determined with a reproducibility of 1 to 2 per cent. The difference between the values found for serum calcium with the Cal-red and the oxalate method had a standard deviation of ±3.32 per cent. Serum magnesium can be determined as the difference of two simple titrations. Phosphate levels up to 30 mg. per 100 ml. P did not interfere with the determination in serum, even when the calcium level was raised to about 20 mg. per 100 ml. Up to products of 80(Ca X P, expressed in mg. per 100 ml.) there was no interference, in inorganic salt solutions. At higher products drift occurred, but the addition of some citrate to the solutions enabled the attainment of sharp end points at Ca X P products up to approximately 1000. Urinary calcium was determined satisfactorily, without the occurrence of drift, if citrate was added to the solution. Magnesium did not interfere appreciably, giving only 1 per cent higher readings at levels of 20 mg. per 100 ml. The interference of copper and iron was removed by the addition of sodium cyanide.

Technology and cost-effectiveness in knee arthroplasty: computer navigation and robotics.

Abstract: Our aim in this article is to describe the impact that navigation technology has had on the market share of a community hospital and, specifically, to determine whether a high-volume surgeon using these technologies actually costs the hospital more than other surgeons at the same hospital and more than national means. In addition, we develop a comparable cost-effectiveness model for robotic technology in unicompartmental knee arthroplasty to demonstrate the potential cost-effectiveness at the same hospital.

Pregnancy loss, polycystic ovary syndrome, thrombophilia, hypofibrinolysis, enoxaparin, metformin.

Abstract: Thrombophilia, hypofibrinolysis, and polycystic ovary syndrome (PCOS) are associated with recurrent pregnancy loss (RPL) and spontaneous abortion (SAB) alone and concurrently. The efficacy and safety of combined enoxaparin-metformin was prospectively assessed in women with PCOS with one or more previous SAB, thrombophilia, and/or hypofibrinolysis. Twenty-four white women with PCOS were studied; 23 with previous pregnancies, seven with RPL of unknown etiology (>/=three consecutive pregnancy losses 21.1 U/mL) of the PAI-1 gene product, plasminogen activator inhibitor activity (PAI-Fx) (33% vs. 8%, p(f) =. 018), and for high factor VIII (>150%) (22% vs. 0%, p(f) = .037). Of the 24 women, 23 had 65 previous pregnancies without metformin or enoxaparin, with 18 live births, 46 SAB (71%), and one elective abortion. On metforminenoxaparin, the same 23 women had 26 current pregnancies (28 fetuses), with 20 live births, two normal pregnancies 13 weeks or longer, and six SAB (21%), 3.4-fold lower than previous gestations (McNemar's S = 33.6, p <. 0001). There were no adverse maternal or fetal therapy effects. Enoxaparin-metformin reduces pregnancy loss in women with PCOS with one or more previous SAB, who also have thrombophilia and/or hypofibrinolysis.

Abnormal lung growth and the development of pulmonary hypertension in the Fawn-Hooded rat.

Abstract: The Fawn-Hooded rat (FHR) strain develops accelerated and severe pulmonary hypertension when exposed to slight decreases in alveolar P O 2 . We recently observed that adult FHR lungs showed a strik...