Institution
Johannes Kepler University of Linz
Education•Linz, Oberösterreich, Austria•
About: Johannes Kepler University of Linz is a education organization based out in Linz, Oberösterreich, Austria. It is known for research contribution in the topics: Computer science & Thin film. The organization has 6605 authors who have published 19243 publications receiving 385667 citations.
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors presented a method for constructing an approximate classical description of a quantum state using very few measurements of the state, called a "classical shadow", which can be used to predict many different properties.
Abstract: Predicting the properties of complex, large-scale quantum systems is essential for developing quantum technologies. We present an efficient method for constructing an approximate classical description of a quantum state using very few measurements of the state. This description, called a ‘classical shadow’, can be used to predict many different properties; order $${\mathrm{log}}\,(M)$$
measurements suffice to accurately predict M different functions of the state with high success probability. The number of measurements is independent of the system size and saturates information-theoretic lower bounds. Moreover, target properties to predict can be selected after the measurements are completed. We support our theoretical findings with extensive numerical experiments. We apply classical shadows to predict quantum fidelities, entanglement entropies, two-point correlation functions, expectation values of local observables and the energy variance of many-body local Hamiltonians. The numerical results highlight the advantages of classical shadows relative to previously known methods. An efficient method has been proposed through which the properties of a complex, large-scale quantum system can be predicted without fully characterizing the quantum state.
347 citations
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TL;DR: The motivation behind this preliminary analysis is attainment of: interoperability between adaptive learning systems; reuse of adaptive learning materials; and, the facilitation of adaptively supported, distributed learning activities.
Abstract: This paper examines the sufficiency of existing eLearning standards for facilitating and supporting the introduction of adaptive techniques in computer-based learning systems. To that end, the main representational and operational requirements of adaptive learning environments are examined and contrasted against current eLearning standards. The motivation behind this preliminary analysis is attainment of: interoperability between adaptive learning systems; reuse of adaptive learning materials; and, the facilitation of adaptively supported, distributed learning activities.
343 citations
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Medical University of Vienna1, University of Barcelona2, University of São Paulo3, University of California, San Francisco4, Uppsala University5, Newcastle University6, University of Zurich7, Washington University in St. Louis8, Icahn School of Medicine at Mount Sinai9, University of Paris10, Indiana University11, University of New South Wales12, University of Edinburgh13, University of Bristol14, University of British Columbia15, University of Toronto16, Mayo Clinic17, University of Kentucky18, Niigata University19, University of Pennsylvania20, University of Oxford21, Ludwig Maximilian University of Munich22, Walton Centre23, Northwestern University24, University of Cambridge25, Harvard University26, Imperial College London27, University of Texas Southwestern Medical Center28, University of Debrecen29, University of Sheffield30, University of Pittsburgh31, University of Geneva32, University of Sydney33, University of Manchester34, Boston University35, Alfred Hospital36, University of Washington37, Netherlands Institute for Neuroscience38, Rush University Medical Center39, Heidelberg University40, Saitama Medical University41, University of Ulm42, Katholieke Universiteit Leuven43, University of Basel44, Johns Hopkins University45, University of California, Los Angeles46, Johannes Kepler University of Linz47, New York University48, University of Ottawa49, Kanazawa University50
Abstract: Pathological accumulation of abnormally phosphorylated tau protein in astrocytes is a frequent, but poorly characterized feature of the aging brain. Its etiology is uncertain, but its presence is sufficiently ubiquitous to merit further characterization and classification, which may stimulate clinicopathological studies and research into its pathobiology. This paper aims to harmonize evaluation and nomenclature of aging-related tau astrogliopathy (ARTAG), a term that refers to a morphological spectrum of astroglial pathology detected by tau immunohistochemistry, especially with phosphorylation-dependent and 4R isoform-specific antibodies. ARTAG occurs mainly, but not exclusively, in individuals over 60 years of age. Tau-immunoreactive astrocytes in ARTAG include thorn-shaped astrocytes at the glia limitans and in white matter, as well as solitary or clustered astrocytes with perinuclear cytoplasmic tau immunoreactivity that extends into the astroglial processes as fine fibrillar or granular immunopositivity, typically in gray matter. Various forms of ARTAG may coexist in the same brain and might reflect different pathogenic processes. Based on morphology and anatomical distribution, ARTAG can be distinguished from primary tauopathies, but may be concurrent with primary tauopathies or other disorders. We recommend four steps for evaluation of ARTAG: (1) identification of five types based on the location of either morphologies of tau astrogliopathy: subpial, subependymal, perivascular, white matter, gray matter; (2) documentation of the regional involvement: medial temporal lobe, lobar (frontal, parietal, occipital, lateral temporal), subcortical, brainstem; (3) documentation of the severity of tau astrogliopathy; and (4) description of subregional involvement. Some types of ARTAG may underlie neurological symptoms; however, the clinical significance of ARTAG is currently uncertain and awaits further studies. The goal of this proposal is to raise awareness of astroglial tau pathology in the aged brain, facilitating communication among neuropathologists and researchers, and informing interpretation of clinical biomarkers and imaging studies that focus on tau-related indicators.
343 citations
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TL;DR: The circumstances under which space-filling superiority holds are reviewed, some new arguments are provided and some motives to go beyond space- filling are clarified.
Abstract: When setting up a computer experiment, it has become a standard practice to select the inputs spread out uniformly across the available space. These so-called space-filling designs are now ubiquitous in corresponding publications and conferences. The statistical folklore is that such designs have superior properties when it comes to prediction and estimation of emulator functions. In this paper we want to review the circumstances under which this superiority holds, provide some new arguments and clarify the motives to go beyond space-filling. An overview over the state of the art of space-filling is introducing and complementing these results.
342 citations
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Hebrew University of Jerusalem1, Fundamental Research on Matter Institute for Atomic and Molecular Physics2, Fritz Haber Institute of the Max Planck Society3, University of Manchester4, Johannes Kepler University of Linz5, École Polytechnique Fédérale de Lausanne6, University of Chicago7, Max Planck Society8
TL;DR: A review of the experimental and theoretical advances made in the last several decades in understanding the structure, dynamics, and transport of the proton and hydroxide ions in different aqueous environments, ranging from water clusters to the bulk liquid and its interfaces with hydrophobic surfaces is provided.
Abstract: Understanding the structure and dynamics of water's constituent ions, proton and hydroxide, has been a subject of numerous experimental and theoretical studies over the last century. Besides their obvious importance in acid-base chemistry, these ions play an important role in numerous applications ranging from enzyme catalysis to environmental chemistry. Despite a long history of research, many fundamental issues regarding their properties continue to be an active area of research. Here, we provide a review of the experimental and theoretical advances made in the last several decades in understanding the structure, dynamics, and transport of the proton and hydroxide ions in different aqueous environments, ranging from water clusters to the bulk liquid and its interfaces with hydrophobic surfaces. The propensity of these ions to accumulate at hydrophobic surfaces has been a subject of intense debate, and we highlight the open issues and challenges in this area. Biological applications reviewed include proton transport along the hydration layer of various membranes and through channel proteins, problems that are at the core of cellular bioenergetics.
342 citations
Authors
Showing all 6718 results
Name | H-index | Papers | Citations |
---|---|---|---|
Wolfgang Wagner | 156 | 2342 | 123391 |
A. Paul Alivisatos | 146 | 470 | 101741 |
Klaus-Robert Müller | 129 | 764 | 79391 |
Christoph J. Brabec | 120 | 896 | 68188 |
Andreas Heinz | 108 | 1078 | 45002 |
Niyazi Serdar Sariciftci | 99 | 591 | 54055 |
Lars Samuelson | 96 | 850 | 36931 |
Peter J. Oefner | 90 | 348 | 30729 |
Dmitri V. Talapin | 90 | 303 | 39572 |
Tomás Torres | 88 | 625 | 28223 |
Ramesh Raskar | 86 | 670 | 30675 |
Siegfried Bauer | 84 | 422 | 26759 |
Alexander Eychmüller | 82 | 444 | 23688 |
Friedrich Schneider | 82 | 554 | 27383 |
Maksym V. Kovalenko | 81 | 360 | 34805 |