Jordan University of Science and Technology

About: Jordan University of Science and Technology is a education organization based out in Irbid, Irbid, Jordan. It is known for research contribution in the topics: Population & Medicine. The organization has 7582 authors who have published 13166 publications receiving 298158 citations. The organization is also known as: JUST.

Endurance exercise training promotes angiogenesis in the brain of chronic/progressive mouse model of Parkinson's Disease.

Abstract: Goals and objectives: The main goal of this study is to evaluate the effect of treadmill exercise on the angiogenesis markers in the striatum (ST) of chronic/progressive parkinsonian mice. Materials and Methods: Forty C57BL/6 albino mice were randomly divided into four groups. Sedentary control (SC, n = 10), exercise control (ExC, n = 10), sedentary Parkinson's (SPD, n = 10), and exercised Parkinson's (ExPD, n = 10). Parkinsonism was induced by the injection with 10 doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, (25 mg/kg) and probenecid (250 mg/kg) over 5 weeks, three days and half a part. Following the induction of parkinsonism, ExPD and ExC animal groups were trained on a modified human treadmill at a speed of 18 m/min, 0 ◦ of inclination, 40 min/day, 5 days/week for 4 weeks. The remaining two groups (SPD and SC) were housed in cages for the same period. At the end of the experiment, the angiogenesis markers; Vascular Endothelial Growth Factor (VEGF) and CD34 were examined in the striatum in the four animal groups. Results: PD resulted in a significant decrease in blood vessel density with the comparison between the sedentary control and PD model animals ( p< 0.005). Four weeks of treadmill exercise training significantly increased angiogenesis in the striatum in ExPD groups ( p< 0.05). Exercise also induced an increase in blood vessel density in the striatum of the control animals, but the change was not significant ( P< 0.3). Conclusion: These data suggest that 4 weeks of treadmill exercise promoted angiogenesis in the brain of chronic Parkinsonian mice, which can partially explain the beneficial role exercise in patients with PD. Further studies are required to determine the mechanism of exercise-induced angiogenesis in PD.

Ovarian cyst formation following GnRH agonist administration in IVF cycles: incidence and impact

Abstract: BACKGROUND: The formation of functional ovarian cysts has been recognized as one of the side effects of GnRH agonist administration. The formation of cysts during IVF treatment may be of no clinical significance or may negatively influence its outcome. The objective of this study was to determine the incidence of ovarian cyst formation following GnRH agonist administration and to examine their effect on IVF outcome. METHODS: A prospective study of 1317 IVF patients who developed one or more functional ovarian cysts of 15 mm following GnRH agonist treatment was performed. Transvaginal ultrasonographic-guided cyst aspiration was carried out in 76 randomly allocated patients out of 122 patients who were found to have functional ovarian cysts before starting ovarian stimulation with gonadotropins. RESULTS: The incidence of follicular cyst formation was 9.3%. Cyst cycles in comparison with noncyst cycles had significantly elevated day 3 basal FSH (mean ± SD of 8.3 ± 3.2 versus 5.3 ± 2.6 mIU/ml, P < 0.05) and required more ampoules of gonadotropins (46.3 ± 16.5 versus 35 ± 14.6, P <0.01). Furthermore, they showed a statistically significant decrease in the quality and number of oocytes retrieved, fertilization rate, number and quality of embryos, implantation and pregnancy rates, with a significant increase in cancellation and abortion rates. Patients with bilateral cysts had a significantly lower number of oocytes and embryos retrieved, with a lower proportion of metaphase II oocytes. They also had a higher proportion of poor quality embryos. Cyst aspiration was not associated with a significant difference in the above parameters. CONCLUSIONS: The incidence of cyst formation during GnRH agonist treatment is lower than previously reported. In such cases, the quality of oocytes and embryos were significantly compromised, with a significant increase in the cycle cancellation rate and a decrease in the implantation and pregnancy rates. Neither conservative management nor cyst aspiration improved the IVF outcome.

Enhanced, Delay Dependent, Intelligent Fusion for INS/GPS Navigation System

Abstract: Low-cost navigation systems, deployed for ground vehicles' applications, are designed based on the loosely coupled fusion between the global positioning system (GPS) and the inertial measurement unit (IMU). However, low-cost GPS receivers provide the position and velocity of the vehicle at a lower sampling rate than the IMU-sampled vehicle dynamics. In addition, the GPS measurements might be missed or delayed due to the receiver's inability to lock on the signal or due to obstruction from neighboring vehicles or infrastructures. In this paper, an architecture based on an adaptive neuro-fuzzy inference system is proposed for fusing the GPS/IMU measurements. This integration incorporates the variable delay between the IMU and GPS signals as an additional input to the fusion system. In addition, once the GPS signal becomes available, the measurement is used as a correction reference value to provide an enhancement to the estimation accuracy. The performance of the proposed method is initially demonstrated using a GPS/IMU simulation environment. Subsequently, an experimental test is also conducted to validate the performance of the method.

Phenotypic diversity and revision of the nomenclature for autosomal recessive amelogenesis imperfecta.

Abstract: Purpose The purpose of this study was to characterize the phenotype in 9 families with autosomal recessive amelogenesis imperfecta (ARAI), and to propose a classification system allowing inclusion and delineation of diverse ARAI phenotypes. Study design Nine families with ARAI were evaluated clinically and radiographically. Exfoliated and extracted teeth were examined via light and scanning electron microscopy, with the enamel in one case evaluated by amino acid analysis. Results The 9 families demonstrated diverse ARAI phenotypes including localized hypoplastic, generalized thin hypoplastic, hypocalcified and hypomaturation AI types. Conclusions Some ARAI phenotypes observed in this study and reported in the literature cannot be classified using currently accepted ARAI nomenclature. Therefore, we propose a revised nomenclature permitting both classification of all ARAI clinical forms and inclusion of anticipated molecular-based nomenclature, such as now exists for some X-linked and autosomal dominant AI subtypes.