Jordan University of Science and Technology

About: Jordan University of Science and Technology is a education organization based out in Irbid, Irbid, Jordan. It is known for research contribution in the topics: Population & Health care. The organization has 7582 authors who have published 13166 publications receiving 298158 citations. The organization is also known as: JUST.

An acellular biologic scaffold treatment for volumetric muscle loss: results of a 13-patient cohort study.

Abstract: Volumetric muscle loss (VML) is a severe and debilitating clinical problem. Current standard of care includes physical therapy or orthotics, which do not correct underlying strength deficits, and surgical tendon transfers or muscle transfers, which involve donor site morbidity and fall short of restoring function. The results of a 13-patient cohort study are described herein and involve a regenerative medicine approach for VML treatment. Acellular bioscaffolds composed of mammalian extracellular matrix (ECM) were implanted and combined with aggressive and early physical therapy following treatment. Immunolabeling of ultrasound-guided biopsies, and magnetic resonance imaging and computed tomography imaging were performed to analyse the presence of stem/progenitor cells and formation of new skeletal muscle. Force production, range-of-motion and functional task performance were analysed by physical therapists. Electrodiagnostic evaluation was used to analyse presence of innervated skeletal muscle. This study is registered with ClinicalTrials.gov, numbers NCT01292876. In vivo remodelling of ECM bioscaffolds was associated with mobilisation of perivascular stem cells; formation of new, vascularised, innervated islands of skeletal muscle within the implantation site; increased force production; and improved functional task performance when compared with pre-operative performance. Compared with pre-operative performance, by 6 months after ECM implantation, patients showed an average improvement of 37.3% (P<0.05) in strength and 27.1% improvement in range-of-motion tasks (P<0.05). Implantation of acellular bioscaffolds derived from ECM can improve strength and function, and promotes site-appropriate remodelling of VML defects. These findings provide early evidence of bioscaffolding as a viable treatment of VML.

Treatment of mandibular odontogenic keratocysts.

Abstract: Objective. The purpose of this study was to report our experience with surgical treatment of 31 mandibular odontogenic keratocysts, with special reference to their recurrence, and to review the literature on this subject. Study design. A retrospective analysis was conducted of all odontogenic cysts treated in the Department of Oral Surgery and Oral Medicine at Jordan University of Science and Technology between 1989 and 1995. Of a total of 227 odontogenic cysts, 31 odontogenic keratocysts were histopathologically diagnosed preoperatively. They were surgically treated through an intraoral approach by resection without continuity defects. The lower border of the mandible and/or the posterior border of the ramus was left intact. In cases where teeth were in continuity with the lesion, they were extracted. In cases where cortical perforation occurred, any associated overlying mucoperiosteum was excised. All patients were reviewed annually for a follow-up period of 2 to 8 years. Results. All odontogenic keratocysts were found in the mandible. Of these, 23 were in the ramus and angular region (74.2%) and 8 were located in the body of the mandible. No recurrences of the operated odontogenic keratocysts were observed during the follow-up period. Conclusion. Our findings indicate that removal of odontogenic keratocysts by resection without continuity defects is a satisfactory method of treatment.

Complexity reduction of the NLMS algorithm via selective coefficient update

Abstract: This article proposes an algorithm for partial update of the coefficients of the normalized least mean square (NLMS) finite impulse response (FIR) adaptive filter. It is shown that while the proposed algorithm reduces the complexity of the adaptive filter, it maintains the closest performance to the full update NLMS filter for a given number of updates. Analysis of the MSE convergence and steady-state performance for independent and identically distributed (i.i.d.) signals is provided for the extreme case of one update/iteration.