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June

About: June is a based out in . It is known for research contribution in the topics: Layer (electronics) & Signal. The organization has 1671 authors who have published 968 publications receiving 21781 citations. The organization is also known as: Jun & 6. month.


Papers
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Journal ArticleDOI
16 Jan 2008-Boreas
TL;DR: In this paper, a proposal for a common chronostratigraphical classification of the Quaternary in Norden (and partly continental NW Europe) is made, based on the sequence of glacials/interglacials.
Abstract: Principles and terminology for classification of the Quaternary are discussed, including lithostratigraphy, biostratigraphy. morphostratigraphy, climatostratigraphy and chronostratigraphy. The main conclusion is a proposal for a common chronostratigraphical classification of the Quaternary in Norden (and partly continental NW Europe). The Quaternary is subdivided into the Pleistocene and the Holocene Series. The Pleistocene is further subdivided into several provisional stages (Weichselian, Eemian, etc.), based on the sequence of glacials/interglacials. but with the boundaries preferably defined by stratotypes. The Late Weichselian and the Flandrian (Holocene) are subdivided into chronozoncs (Bolling, Older Dryas, Allerod, Younger Dryas, Preboreal, Boreal, Atlantic, Subboreal, Subatlantic) with the boundaries dcfined in conventional radiocarbon years.

1,103 citations

Journal ArticleDOI
TL;DR: In this paper, the authors outline the climate forcings and setup of the Met Office Hadley Centre ESM, HadGEM2-ES for the CMIP5 set of centennial experiments.
Abstract: . The scientific understanding of the Earth's climate system, including the central question of how the climate system is likely to respond to human-induced perturbations, is comprehensively captured in GCMs and Earth System Models (ESM). Diagnosing the simulated climate response, and comparing responses across different models, is crucially dependent on transparent assumptions of how the GCM/ESM has been driven – especially because the implementation can involve subjective decisions and may differ between modelling groups performing the same experiment. This paper outlines the climate forcings and setup of the Met Office Hadley Centre ESM, HadGEM2-ES for the CMIP5 set of centennial experiments. We document the prescribed greenhouse gas concentrations, aerosol precursors, stratospheric and tropospheric ozone assumptions, as well as implementation of land-use change and natural forcings for the HadGEM2-ES historical and future experiments following the Representative Concentration Pathways. In addition, we provide details of how HadGEM2-ES ensemble members were initialised from the control run and how the palaeoclimate and AMIP experiments, as well as the "emission-driven" RCP experiments were performed.

843 citations

Journal ArticleDOI
TL;DR: Findings demonstrate diabetes increases the risk of developing destructive periodontal disease about threefold and in a manner which cannot be explained on the basis of age, sex, and hygiene or other dental measures.
Abstract: The relationship between diabetes mellitus and oral health status was determined in Pima Indians from the Gila River Indian Community in Arizona. This tribe of native Americans has the world's highest reported incidence and prevalence of non-insulin-dependent (type 2) diabetes mellitus. The probing attachment level, alveolar bone loss, age, sex, Calculus Index, Plaque Index, Gingival Index, fluorosis, and DMFT as well as the diabetic status was assessed in 1,342 Pima Indians who were at least partially dentate. The prevalence and severity of destructive periodontal disease was determined by measuring probing attachment loss and radiographically apparent interproximal crestal alveolar bone loss, two independent but correlated indicators of periodontal destruction. Only diabetic status, age, and the presence of subgingival calculus were significantly associated with both increased prevalence and greater severity of destructive periodontal disease in this population. Diabetic status was significantly and strongly related to both the prevalence and severity of disease after adjusting for the effects of demographic variables and several indices of oral health including the Plaque Index. Subjects with type 2 diabetes have an increased risk of destructive periodontitis with an odds ratio of 2.81 (95% confidence interval 1.91 to 4.13) when attachment loss is used to measure the disease. The odds ratio for diabetic subjects was 3.43 (95% confidence interval 2.28 to 5.16) where bone loss was used to measure periodontal destruction. These findings demonstrate tht diabetes increases the risk of developing destructive periodontal disease about threefold. Furthermore, diabetes increases the risk of developing periodontal disease in a manner which cannot be explained on the basis of age, sex, and hygiene or other dental measures.(ABSTRACT TRUNCATED AT 250 WORDS)

657 citations

Journal ArticleDOI
Wildek Penfield1
TL;DR: My own approach to the study of epilepsy, and through it to the functional anatomy of the human brain, was a long journey---blind in the beginning but somewhat inevitable; I shall dcscrihe my journey as a Pilgrim's Progress and hope you will forgive me if it seems no more than a wandering tale of personal adventure in the outset.
Abstract: My own approach to the study of epilepsy, and through it to the functional anatomy of the human brain, was a long journey---blind in the beginning but somewhat inevitable. I shall dcscrihe my journey as a Pilgrim’s Progress and hope you will forgive me if it seems no more than a wandering tale of personal adventure in the outset. We are told that Martin Luther was willing to ‘‘bet’’ (drum wohlte ich schier wettcn) that St. Valentine was thought to bc the patron saint of the falling disease simply because, to the German ear, St. Valcntine sounded like “der Fallenden Sucht”]. Luther himself, it is clear, had a fatal wcakncss for “heresies”. His heresics changed the history of Christendom. Rut in this case I remain unconvinced and orthodox. I prefer to believe in St. Valentine. God knows the vast army of innocent Inen and women and childrcn who suffer from cpilepsy in its many form4 has always had need of a powerful patron saint. Many cpileptics in that army arc my friends. I owe them a wonderful debt of gratitude. For this reason I have comc to Copenhagen--to pay tribute to St. Valcntine before this distinguished Society that honours him. Sir Charles Sherrington was Professor of Physiology a t Oxford whcn I was a medical student. He was always the student of function in the nervous system, always speculating on the “how” of integration. In his laboratory, questions were put to the experimental “preparation” for authoritative answer. Later, during my hospital service in Boston, 1 watched Harvey Cushing in his surgical clinic a t the Peter Bent Brigham Hospital. He was then demonstrating that neurosurgery could be made a rcspcctablc specialty with a low’ mortality rate. But, a t that time, it was almost exclusively the surgery of tuinours and of pain. For me, the great

469 citations

Patent
03 Jun 1994
TL;DR: In this paper, a method for inducing a population of T cells to proliferate by activating the population of cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the accessory molecule is described.
Abstract: Methods for inducing a population of T cells to proliferate by activating the population of T cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the accessory molecule are described. T cell proliferation occurs in the absence of exogenous growth factors or accessory cells. T cell activation is accomplished by stimulating the T cell receptor (TCR)/CD3 complex or the CD2 surface protein. To induce proliferation of an activated population T cells, an accessory molecule on the surface of the T cells, such as CD28, is stimulated with a ligand which binds the accessory molecule. The T cell population expanded by the method of the invention can be genetically transduced and used for immunotherapy or can be used in methods of diagnosis.

465 citations


Authors

Showing all 1671 results

NameH-indexPapersCitations
Craig B. Thompson195557173172
Carl H. June15683598904
Mark A. Rubin14569995640
Anthony Atala125123560790
Samuel Z. Goldhaber12478469216
Chong-Yu Xu11393757061
Peter D. Sly10383744815
Kyle S. Dawson10328958608
Peter C.B. Phillips9973573883
Michael H. Weisman9246039567
Vernon L. Smith9148236165
Helmut Schwarz88130037801
Alan J. Wein87116447916
Andrew C. Novick8653930822
Georg Bartsch8450523329
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202117
202011
201914
201818
201711
201621