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Institution

Kadi Sarva Vishwavidyalaya

EducationGandhinagar, Gujarat, India
About: Kadi Sarva Vishwavidyalaya is a(n) education organization based out in Gandhinagar, Gujarat, India. It is known for research contribution in the topic(s): Matrix (chemical analysis) & Liquid chromatography–mass spectrometry. The organization has 131 authors who have published 158 publication(s) receiving 1343 citation(s).
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Journal ArticleDOI
TL;DR: Results indicated that the isolate isolated from petroleum-polluted soil has potential to be used for ex-situ and in-Situ bioremediation of hydrocarbon pollutants and could have promising applications in petrochemical industry.
Abstract: The aim of this work was to study the potential of an indigenous strain of Pseudomonas aeruginosa NCIM 5514, isolated from petroleum-polluted soil, for the biodegradation of crude petroleum oil. The isolate completely decolorized 2,6-dichlorophenol indophenol in 120h when grown at (37±1°C), indicating its hydrocarbon utilizing nature. Ex situ biodegradation study was performed to find out quantitative utilization and biodegradation of paraffin(s) present in crude oil. When the culture was grown in Bushnell-Hass medium containing crude oil (3%,v/v) at 37°C, 180rpm for 60days, the viscosity of the oil was reduced from 1883cp to 1002cp. Gravimetric and gas chromatographic analysis showed 61.03% and 60.63% of biodegradation of C8-C36+ hydrocarbons, respectively. These results indicated that the isolate has potential to be used for ex-situ and in-situ bioremediation of hydrocarbon pollutants and could have promising applications in petrochemical industry.

143 citations


Journal ArticleDOI
TL;DR: The present research work was undertaken with a mandate to study carbon spectrum utilization and structural characterization of biosurfactant produced by indigenous Pseudomonas aeruginosa NCIM 5514, which showed unique properties to utilize a large number of carbon sources effectively for production of biosURfactant, although glucose was the best carbon substrate.
Abstract: The present research work was undertaken with a mandate to study carbon spectrum utilization and structural characterization of biosurfactant produced by indigenous Pseudomonas aeruginosa NCIM 5514, which showed unique properties to utilize a large number of carbon sources effectively for production of biosurfactant, although glucose was the best carbon substrate. In Bushnell-Hass medium supplemented with glucose (1%, w/v), 3.178±0.071g/l biosurfactant was produced by this isolate in 96h. The biosurfactant produced showed surface tension and emulsification activity values from 29.14±0.05 to 62.29±0.13mN/m and 88.50±1.96 to 15.40±0.91%, respectively. Toluene showed highest emulsification activity followed by kerosene. However, kerosene exhibited emulsion stability for 30days. Biosurfactant was characterized as a mixture of di-rhamnolipid (Rha-Rha-C10-C14:1) and mono-rhamnolipid (Rha-C8-C10) by FTIR, ESI-MS and LC-MS techniques. High biosurfactant yield opens up doors for the isolate to find utility in various industries.

88 citations


Journal ArticleDOI
TL;DR: It was concluded that CP loaded gel could be a promising formulation for effective treatment of vitiligo.
Abstract: The aim of the present investigation was to evaluate microemulsion as a vehicle for dermal drug delivery and to develop microemulsion based gel (MBC) of clobetasol propionate (CP) for the effective treatment of vitiligo. D-Optimal mixture experimental design was adopted to optimize the amount of oil (X(1)), S(mix) (mixture of surfactant and cosurfactant) (X(2)) and water (X(3)) in the microemulsion. The formulations were assessed for globule size (nm) (Y(1)) and solubility of CP in microemulsion (mg/ml) (Y(2)). The microemulsion containing 3% oil, 45% S(mix) and 50% water was selected as the optimized batch (ME). The globule size and solubility of CP in ME were 18.26 nm and 36.42 mg/ml respectively. Transmission electron microscopy showed that ME globules were spherical in shape. Carbopol 934P was used to convert microemulsion containing drug into gel form without affecting its structure. Ex-vivo permeation studies showed that cumulative amount of CP permeated (Q(n)) from ME, MBC and market formulation (MFCP) at 8h after application were 53.6±2.18, 28.43±0.67 and 37.73±0.77 μg cm(-2) respectively. MBC showed greater retention of CP in to skin layers than ME and MFCP. Skin irritation studies showed MBC to be significantly less irritating than MFCP. Photomicrographs and scanning electron micrographs of skin sections treated with MBC showed significant changes in the skin structure, which was attributed to the interaction of microemulsion components with skin resulting in permeation enhancement and retention of CP into skin layers. It was concluded that CP loaded gel could be a promising formulation for effective treatment of vitiligo.

76 citations


Journal ArticleDOI
TL;DR: Scientific and technical information about dyes & dye intermediates and biodegradation of azo dye is provided and role of genetically modified organisms (GMOs) in process of dye degradation and perspectives in this field of research are compiled.
Abstract: Industrialization increases use of dyes due to its high demand in paper, cosmetic, textile, leather and food industries This in turn would increase wastewater generation from dye industrial activities Various dyes and its structural compounds present in dye industrial wastewater have harmful effects on plants, animals and humans Synthetic dyes are more resistant than natural dyes to physical and chemical methods for remediation which makes them more difficult to get decolorize Microbial degradation has been researched and reviewed largely for quicker dye degradation Genetically engineered microorganisms (GEMs) play important role in achieving complete dye degradation This paper provides scientific and technical information about dyes & dye intermediates and biodegradation of azo dye It also compiles information about factors affecting dye(s) biodegradation, role of genetically modified organisms (GMOs) in process of dye(s) degradation and perspectives in this field of research

73 citations


Journal ArticleDOI
Abstract: Rapid industrialization has provided comforts to mankind but has also impacted the environment harmfully. There has been severe increase in the pollution due to several industries, in particular due to dye industry, which generate huge quantities of wastewater containing hazardous chemicals. Although tremendous developments have taken place for the treatment and management of such wastewater through chemical or biological processes, there is an emerging shift in the approach, with focus shifting on resource recovery from such wastewater and also their management in sustainable manner. This review article aims to present and discuss the most advanced and state-of-art technical and scientific developments about the treatment of dye industry wastewater, which include advanced oxidation process, membrane filtration technique, microbial technologies, bio-electrochemical degradation, photocatalytic degradation, etc. Among these technologies, microbial degradation seems highly promising for resource recovery and sustainability and has been discussed in detail as a promising approach. This paper also covers the challenges and future perspectives in this field.

45 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20222
202144
202017
20198
20187
20179