Showing papers by "Kadi Sarva Vishwavidyalaya published in 2015"
TL;DR: The effects of methyl jasmonate (MeJA), an elicitor of plant defense mechanisms, on the biosynthesis of diosgenin, a steroidal saponin, were investigated in six fenugreek varieties and may be considered a promising elicitor for diOSgenin production by fenUGreek plants.
Abstract: The effects of methyl jasmonate (MeJA), an elicitor of plant defense mechanisms, on the biosynthesis of diosgenin, a steroidal saponin, were investigated in six fenugreek (Trigonella foenum-graecum) varieties (Gujarat Methi-2, Kasuri-1, Kasuri-2, Pusa Early Branching, Rajasthan Methi and Maharashtra Methi-5). Treatment with 0.01% MeJA increased diosgenin levels, in 12 days old seedlings, from 0.5%-0.9% to 1.1%-1.8%. In addition, MeJA upregulated the expression of two pivotal genes of the mevalonate pathway, the metabolic route leading to diosgenin: 3-hydroxy-3-methylglutaryl-CoA reductase (HMG) and sterol-3-β-glucosyl transferase (STRL). In particular, MeJA increased the expression of HMG and STRL genes by 3.2- and 22.2-fold, respectively, in the Gujarat Methi-2 variety, and by 25.4- and 28.4-fold, respectively, in the Kasuri-2 variety. Therefore, MeJA may be considered a promising elicitor for diosgenin production by fenugreek plants.
45 citations
25 Jun 2015
TL;DR: The present study concludes that AQ is not influenced by gender, stream of education and family factors, rather it was seen to be influenced by the type of schools.
Abstract: The present research was conducted to understand the Adversity Quotient (AQ) of students who are going to enter into higher education. Higher secondary is the stage from where they move from school to higher education. So, the present research was conducted to study the AQ of 11th standard, English medium school students in Gandhinagar city, Gujarat with reference to various variables. The study was conducted on a sample of 461 boys and girls of 11 th standard school students from Gujarat State Board of Education (GSEB) and Central Board of Secondary Education (CBSE) schools. A self-constructed AQ scale was used to collect data from the students. The collected data was analyzed using statistical techniques like mean, SD and C.R values. Result revealed that there was no significant difference in the mean scores of AQ on the basis of gender, stream of education i.e. Commerce, Science and Arts, and various family variables like nature of the family, size of the family, qualification of parents, parents‟ working status and parents‟ occupation. However, a significant difference was found in the mean scores of AQ of students on the basis of board of School i.e. GSEB and CBSE. The present study concludes that AQ is not influenced by gender, stream of education and family factors, rather it was seen to be influenced by the type of schools. Investigator inquired and understood the AQ profile of higher secondary school students as it is the gate way to higher Education. By understanding the AQ levels of students, the faculty and staffs can be better equipped to support students as they navigate the stressors of college life.
26 citations
Journal Article•
TL;DR: In vivo pharmacokinetics study in Swiss albino rats revealed that encapsulation of Curcumin into solid lipid nanoparticles increased oral bioavailability ofCurcumin to 12 folds when compared with marketed formulation of Raw Curcuming (Adcumin®).
Abstract: Objective : Solid lipid nanoparticles (SLNs) of Curcuminoids were formulated and characterized in order to improve poor oral bioavailability of Curcumin. In vivo pharmacokinetics study in rats was conducted to demonstrate improved oral bioavailability. Methods : High pressure homogenization followed by ultrasonication method was adopted to formulate solid lipid nanoparticles of Curcumin. Compritol 888 ATO and Precirol ATO 5 were explored as solid lipids with LIPOID S 75 being used as surfactant. Freeze dried solid lipid nanoparticles were compared with marketed formulation of Curcumin (Adcumin®) in rat plasma using High Pressure Liquid Chromatography (HPLC) method using ultraviolet (UV) detector. Results : Particle size measurements performed on Solid lipid nanoparticles of Curcumin revealed the mean particle size of 200-300 nm for optimized formulations and entrapment efficiency of close to 80%. Sucrose and Dextrose were suitable cryoprotectants to prepare freeze dried solid lipid nanoparticles. Curcumin loaded solid lipid nanoparticles exhibited sustained release pattern during in vitro release kinetics. Conclusion : In vivo pharmacokinetics study in Swiss albino rats revealed that encapsulation of Curcumin into solid lipid nanoparticles increased oral bioavailability of Curcumin to 12 folds when compared with marketed formulation of Raw Curcumin (Adcumin®).
14 citations
Posted Content•
TL;DR: In this paper, the influence of consumer perception towards green advertising on green purchase intention was examined and the results demonstrated that within consumer perception, environmental knowledge, company image, improved product features, and ethical impact have significant positive influences on green purchasing intention while scepticism towards green claims and credibility have insignificant effect on green consumption.
Abstract: With the increase in the level of consumer awareness towards green products, “Green Marketing” has started gaining importance since 1970s but getting further momentum since last two decades. Many companies have added and/or modified their products and process in order to position themselves as Green. Marketers have directed their focus on advertising as the best communication tool for addressing their environmental concern and changing consumer perception by building green image. Hence, the effect of consumer perception on green purchase behaviour has a major role on companies‟ strategic orientation. Numbers of researches have been carried out to study the influence of perception towards green advertising on purchase intention that suggests the aspect of advertising to bank upon. The aim of this paper is to examine the influence of consumer perception towards green advertising on green purchase intention. In this study, perception of consumers towards green advertisements and purchase intention was measured using relevant variables identified from literature on Likert scale and using factor analysis the data was reduced and correlated. Multiple regression analysis was used to study the influence of perception on purchase intention. The results demonstrated that within consumer perception; environmental knowledge, company image, improved product features, and ethical impact have significant positive influences on green purchase intention while scepticism towards green claims and credibility have insignificant effect on green purchase intention. The outcome identified aspects of green advertising that marketers may use while designing advertising strategies.
13 citations
TL;DR: D-optimal design was used to optimize the amount of components in liquid self nanoemulsifying drug delivery system and the optimized S-SNEDDS was found to be stable and its shelf life was finding to be 2.2 years.
Abstract: The solid-self nanoemulsifying drug delivery system (S-SNEDDS) of Amiodarone hydrochloride (AH) was prepared and evaluated. AH exhibits poor aqueous solubility (0.3-0.5 mg/ml) and therefore variable oral bioavailability. Capmul MCM, Cremophor RH-40 and Propylene glycol were identified as oil, surfactant and co-surfactant for preparing L-SNEDDS. D-optimal design was used to optimize the amount of components in liquid self nanoemulsifying drug delivery system (L-SNEDDS). Optimized AH-L-SNEDDS having 15.8 nm globule size and 99.5 %transmittance was then adsorbed on Neusilin US2 to form solid self nanoemulsifying drug delivery system (AH-SSNEDDS). AH loaded L-SNEDDS and S-SNEDDS were characterized for various physicochemical properties and solid state properties. In vitro dissolution, ex vivo drug release study and In vivo study were performed for pure AH, AH-LSNEDDS and AH-S-SNEDDS. Both AH loaded L-SNEDDS and S-SNEDDS showed more than 95% drug release in 20 min during drug release studies. In vivo study revealed that release of AH from S-SNEDDS was 2.26 times and LSNEDDS was 1.83 times higher than that from suspension when given to rabbits (p < 0.01). The optimized S-SNEDDS was found to be stable and its shelf life was found to be 2.2 years. S-SNEDDS could serve as a potential drug delivery system for AH.
12 citations
Journal Article•
TL;DR: In this article, a selective and robust method for determination of Cape in dried blood spots (DBS) by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was described.
Abstract: Objective: Capecitabine (Cape), the first oral prodrug which belongs to the group of fluoro pyrimidines is the most frequently prescribed anticancer drug for the treatment of metastatic breast and colorectal cancers. The article describes a selective and robust method for determination of Cape in dried blood spots (DBS) by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Methods: Cape fortified DBS was punched and extracted with ethyl acetate using capecitabine-d11 as the internal standard (IS). Chromatographic separation of Cape and IS from endogenous matrix was performed on Phenomenex Gemini C18 (150 × 4.6 mm, 5mm) column under isocratic condition using acetonitrile: 2 mmol ammonium formate (pH 3.0, adjusted with 0.1 % formic acid) (80:20, v/v ) as the mobile phase. Detection and quantification were carried on a triple quadrupole mass spectrometer, using electro spray ionization technique in the positive ionization mode. Results: The method was established over a concentration range of 10-10000 ng/ml. Accuracy, precision, selectivity, recovery, matrix effect and stability of the analyte were also estimated and the results were within the acceptance criteria. Further, precise results were obtained using an optimum spot volume of 10 µl with good spot homogeneity. Blood samples with hematocrit values varying from 24 % to 45 % gave acceptable results with good accuracy and precision. Conclusion: The efficiency of dried blood spot sample preparation, short analysis time and high selectivity permits estimation of Cape in a small blood volume. The validation results suggest that the method is precise, accurate, and reproducible and can be useful in therapeutic drug monitoring of Cape.
9 citations
Posted Content•
TL;DR: In this paper, a study has revealed that overall impact of merger and acquisition is positive on the Indian banking sector and that mergers between the two banks is beneficial for Indian banks.
Abstract: Banking is one of the important sector of Indian economy. This paper is prepare to check that whether is any improvement in financial & stock return in banks in post-merger period. For this purpose, six banks have been selected whose merger is done in duration of 2006-2008. Study is carried out by comparing various financial parameters. Study has revealed that overall impact of merger and acquisition is positive on the Indian banking sector. Merger between the two banks is beneficial for Indian banks.
7 citations
TL;DR: A simple, precise, and rapid stable isotope dilution liquid chromatography-tandem mass spectrometry method has been developed and validated for the quantification of rilpivirine, a non-nucleoside reverse transcriptase inhibitor in human plasma.
Abstract: A simple, precise, and rapid stable isotope dilution liquid chromatography-tandem mass spectrometry method has been developed and validated for the quantification of rilpivirine, a non-nucleoside reverse transcriptase inhibitor in human plasma. Rilpivirine and its deuterated analogue, rilpivirine-d6, used as an internal standard (IS) were quantitatively extracted by liquid-liquid extraction with methyl-tert-butyl ether and diethyl ether solvent mixture from 50 μL plasma. The chromatography was achieved on Gemini C18 (150 × 4.6 mm, 5 µm) analytical column in a run time of 2.2 min. The precursor product ion transitions for rilpivirine (m/z 367.1 128.0) and IS (m/z 373.2 134.2) were monitored on a triple quadrupole mass spectrometer in the positive ionization mode. The linearity of the method was established in the concentration range of 0.5–200 ng/mL. The mean extraction recovery for rilpivirine (94.9%) and IS (99.9%) from spiked plasma samples was consistent and reproducible. The IS-normalized matrix factors for rilpivirine ranged from 0.98 to 1.02 across three quality controls. Bench top, freeze-thaw, wet extract, and long-term stability of rilpivirine was examined in spiked plasma samples. The application of the method was demonstrated by a bioequivalence study with 25 mg rilpivirine tablet formulation in 40 healthy subjects. The assay reproducibility was shown by reanalysis of 200 study samples and the % change in the concentration of repeat values from the original values was within ±15%. Copyright © 2014 John Wiley & Sons, Ltd.
6 citations
Posted Content•
TL;DR: In this paper, a comparison between pre and post-merger financial performance in terms of net profit margin, return on net worth and return on long-term fund is done by applying Mean score and paired sample t-test.
Abstract: Banking Industry plays an important role in the economic development of India. For strengthening structure of banks, merger is adopted. This study is undertaken with an objective to check improvement in financial performance of banks after merger. This study is undertaken on selected 4 banks where 2 banks are private sector banks and 2 public sector banks. For this study, data of 10 years, i.e. 5 years before merger and 5 years after merger are considered. A comparison between pre and post-merger financial performance in terms of net profit margin, return on net worth, return on long-term fund and return on assets is done. This Study is undertaken by applying Mean score and paired sample t-test. For IDBI Bank, merger has improved financial performance where as for other banks merger remain somewhat beneficial as par as financial performance is concern. Overall impact of merger and acquisition is positive on Indian banking sector. It can be concluded that merger between the two banks is beneficial for Indian banks. Merger does not resulted in improvement of financial performance of any bank. This study is useful to investors and depositors to take their investment decisions.
5 citations
16 Apr 2015
TL;DR: This paper analyzes the present GUI Grid - Alchemi with its components and challenges and proposes a toolkit-Scady which solves the challenges of AlChemi and provides higher performance.
Abstract: Grid computing has resulted in faster execution of applications. Day by day the requirement for execution speed of applications is increasing. To achieve this, suitable middleware is needed and to be configured requirement specific. An application can be executed faster only when there is no node failure or network failure. Moreover, at run time, if a node fails, there should be some alternative arrangement to reconfigure other node to complete the task which was supposed to be done by the failed node. Thus, a middleware is needed that can be configured according to the requirements of the application. Such a middleware would help in increasing the performance of the application. In most of the middleware available presently, dynamic configuration is not facilitated. This has become one of the reasons for the failure of adoption or implementation of Grid in many organizations. This paper analyzes the present GUI Grid - Alchemi with its components and challenges. It also proposes a toolkit-Scady which solves the challenges of Alchemi and provides higher performance. Two experiments are done and their result analysis shows the performance of the proposed toolkit.
5 citations
TL;DR: A selective and rapid high-performance liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of raltegravir using ralTeg Gravir-d3 as an internal standard (IS).
Posted Content•
TL;DR: In this article, the authors examined the factors that consumers perceive as important attributes to a green home while making a purchase and identified the dimensions that green marketers may focus upon while marketing green homes compared to conventional homes.
Abstract: There is a gradual and steady growth observed among consumers all over the world regarding protection of environment and depletion of natural resources, which have led to changes in consumption pattern among them. This has led to the addition of green marketing notion as a third dimension in the relationship between man and environment. It includes development of sustainable and socially responsible products and services for consumers without compromising the conventional benefits. Hence, nowadays-green marketing is widely adopted by the marketers around the world with a hope to capitalize on this by developing strategies that allow consumers to integrate green products into their lifestyles. This paper examines the factors that consumers perceive as important attributes to a green home while making a purchase. The results identify the dimensions that green marketers may focus upon while marketing green homes compared to conventional homes.
Posted Content•
TL;DR: In this article, the authors examined the causal linkages among equity markets to better understand how shocks in one market are transmitted to other markets by applying various analytical tools such as correlation, unit root test (ADF test), and granger causality test were applied in study to find co movement and dependency of Indian market over selected markets.
Abstract: The Bombay stock exchange, Hong Kong Stock Exchange, Tokyo Stock Exchange & Shanghai Stock Exchange are among the oldest exchanges in Asia. The Study was carried out with objective to examine the causal linkages among equity markets to better understand how shocks in one market are transmitted to other markets. The study was done by taking data from 1/3/2000 to till 4/6/2011. The study was done by taking stock price data of BSE, HANGSENG, TSE & SSE. Various analytical tools such as correlation, unit root test (ADF test) and granger causality test were applied in study to find co movement & dependency of Indian market over selected markets. The correlation of daily prices gives an outcome that BSE is highly correlated with Hangseng & SSE. The granger causality test reveals an outcome that BSE is not granger cause by any of the selected market. Over all it can conclude that the selected markets are not much depending on each other.
TL;DR: This paper delves into the optimization of queries by recommending indices which reduces cost of the queries and improves performance ofThe queries.
Abstract: ETL (Extraction-Transformation-Loading) process is responsible for extracting data from several sources, cleansing, transforming, integrating and loading into a data warehouse Extraction process accesses large amount of data by executing several complex queries in source databases These queries are repetitive and executed at regular interval to refresh the data warehouse Extraction of data from source must be completed in a certain time window; hence it is necessary to optimize its execution time In this paper, we delve into the optimization of queries by recommending indices which reduces cost of the queries and improves performance of the queries
Posted Content•
TL;DR: In this paper, the attitude of teachers of higher education towards Internet learning with related to e-learning was studied and different statistical tools like descriptive statistics, reliability test, one way ANNOVA, Chi-square analysis, factor analysis and independent t-test were used.
Abstract: E-learning is an extremely adaptable technology that can be used to cover different delivery modes-self-paced, interactive or live learning can match the varied training needs. The main objective of this study is to study the attitude of teachers of higher education towards Internet learning with related to e-learning. We used descriptive research design in this study. Personal Interview was conducted through questionnaire. Non-probability sampling method is used because it is relied on the personal judgment of the researcher. We used different statistical tools like descriptive statistics, reliability test, one way ANNOVA, Chi-square analysis, factor analysis and independent t-test. This study found that Internet and electronic resources cannot replace physical resources. Basic problem of internet learning is to be most important factors that affect to the internet learning. Time spends on Internet learning and experience in education sector of the respondent is independent to each other.
TL;DR: The ability of ensemble techniques to improve the accuracy of basic J48 algorithm and Naïve Bayes algorithm is focused on.
Abstract: This Classification using ensemble generally combines multiple classifiers that results in the improvement in the accuracy of the classification. Experimenting with the same dataset using the single classifier provides lesser accuracy than ensemble techniques. Many researches have been carried out using the technique of combining the predictions of multiple classifiers to generate a single classifier. The produced classifiers provide more accurate results than any individual classifier. This paper focuses on the ability of ensemble techniques to improve the accuracy of basic J48 algorithm. Ensemble techniques like Bagging and Boosting improved the efficiency of the J48 classifier. Experiments have been carried out on many datasets taken from UCI repository to investigate the effects of ensemble techniques on J48 and Naïve Bayes algorithm. WEKA tool is used to measure the effectiveness of a classifier model.