scispace - formally typeset
Search or ask a question

Showing papers by "Kadi Sarva Vishwavidyalaya published in 2021"


Journal ArticleDOI
TL;DR: In this article, the most advanced and state-of-art technical and scientific developments about the treatment of dye industry wastewater, which include advanced oxidation process, membrane filtration technique, microbial technologies, bio-electrochemical degradation, photocatalytic degradation, etc.
Abstract: Rapid industrialization has provided comforts to mankind but has also impacted the environment harmfully. There has been severe increase in the pollution due to several industries, in particular due to dye industry, which generate huge quantities of wastewater containing hazardous chemicals. Although tremendous developments have taken place for the treatment and management of such wastewater through chemical or biological processes, there is an emerging shift in the approach, with focus shifting on resource recovery from such wastewater and also their management in sustainable manner. This review article aims to present and discuss the most advanced and state-of-art technical and scientific developments about the treatment of dye industry wastewater, which include advanced oxidation process, membrane filtration technique, microbial technologies, bio-electrochemical degradation, photocatalytic degradation, etc. Among these technologies, microbial degradation seems highly promising for resource recovery and sustainability and has been discussed in detail as a promising approach. This paper also covers the challenges and future perspectives in this field.

277 citations


Journal ArticleDOI
TL;DR: In this paper, the authors present and discuss trends and scientific developments about recovery of value-added products from dye industry effluent with emphasis on nanotechnological approaches and microbial electrochemical technologies (METs).
Abstract: Increased population and industrialization generate a large number of organic pollutants that create problems on the planet earth. The level of freshwater is reducing which has pushed the society to reuse/recycle wastewater. Eco-friendly and economically sound treatment of industrial wastewater has attracted global attention and hence is a thrust area of research. Organic compounds rich wastewater can be used to generate bioenergy and value-added products from the resource recovery point of view. Wastewater treatment(s) can be used to trap energy from industrial effluents in form of biofuel, bioenergy and biogas. Recovered products can be used in various ways such as recovered nutrients for (bio)fertilizer production and algal biomass for bioplastic production. Microbial electrochemical technology is a promising approach for resource recovery. This review article aims to present and discuss trends and scientific developments about recovery of value-added products from dye industry effluent. It also provides state-of-art technical information about technologies for remediation of pollutants from dye industry effluent with emphasis on nanotechnological approaches and microbial electrochemical technologies (METs). It narrates literature on classification and properties of dyes, effects of dye pollutants on environment and human health and factors affecting degradation of dyes. Generation of bioenergy and recovery of valuables from dye industrial wastewater along with challenges and perspectives of this research area have been covered.

75 citations


Journal ArticleDOI
TL;DR: In this paper, the authors have discussed technologies and products obtained through bio-routes together with the integrated system of solid waste management, challenges, innovations and perspectives in this field.

57 citations


Journal ArticleDOI
TL;DR: In this article, a review of emerging strategies and monitoring tools for municipal solid waste management is presented, which comprehensively covers environmental and economic relevance of waste management technologies based on innovations achieved through the integration of approaches.

50 citations


Journal ArticleDOI
TL;DR: In this article, a review of the literature about recent technological advancements in the area of minimizing waste content and electricity generation is presented, which focuses on the enhanced generation of biogas and highlights challenges, knowledge gaps, and future research direction.
Abstract: Rise in industrialization and urbanization has resulted in problems like uprising energy demand, voluminous waste generation, and environmental effects. As a consequence, implementing an efficient solid waste management strategy is gaining momentum. The urgency becomes more evident as out of 17 Sustainable Development Goals majority of goals and their targets have a direct link to solid waste management. Public awareness is essential for proper waste management as well as social and demographic issues. The present review intends to expand the literature about recent technological advancements in the area of minimizing waste content and electricity generation. It also covers the conversion of energy from waste with the help of techniques like incineration, gasification, plasma gasification, co-gasification, composting, vermicomposting, co-composting, anaerobic digestion, and co-digestion. These techniques are utilized to convert municipal solid waste into a suitable source for renewed energy that produces heat and electricity and other byproducts in risk-free and environmentally friendly way(s). More precisely, this paper focuses on the enhanced generation of biogas. This review also highlights challenges, knowledge gaps, and future research direction(s).

39 citations


Journal ArticleDOI
01 Aug 2021
TL;DR: Light is shed on recent advances of NMs driven biosensing phenomenon, emphasizing the healthcare perspective, to shed light on the most widely used nanomaterials for biosensing.
Abstract: Of late, biosensing is receiving mounting expectations due to a pressing need for swift and accurate stimulus detection. Sensing via biological moieties has outmoded conventional diagnosis vis-a-vis processing time, skilled manpower and detection accuracy. Screening optimal analyte-stimulus interaction remains crux of biosensing, wherein surface engineering remains vital. The nanomaterials have impelled biological sensing accuracy and robustness comprising tunable electrochemical and physico-mechanical responses, thanks to their versatile shape and size dependent physical and chemical attributes. Closer energy levels with quantum mechanical feasibility distinguish nanomaterials from bulk counterparts for an accurate tracking of interacting coordinates. Till date, the most widely used nanomaterials for biosensing include Au nanoparticles, graphene based assemblies, carbon nanotubes and magnetic nanoparticles. Steadfast preparation mechanisms and stout surface engineering are the driving forces for a biosensing suitability of these entities. With such intent, this article sheds light on recent advances of NMs driven biosensing phenomenon, emphasizing the healthcare perspective.

37 citations


Journal ArticleDOI
TL;DR: In this article, the authors discuss the opportunities, benefits, and challenges of blockchain technology and to assist the research community in understanding the same, and also discuss the taxonomy, application/use-cases, consensus mechanisms, prospective research, future directions, and related technologies.

34 citations


Journal ArticleDOI
TL;DR: The potent lipase producing strain of actinomycete was optimized for pH, temperature, inoculum size, carbon and nitrogen sources and Nocardiopsis alba was selected as the best lipase producer.
Abstract: Actinomycete strains from cottonseed soap-stock (a dark gelatinous waste from oil refinery) were obtained. Cultures were analyzed for the enzyme lipase, protease and cellulase production using plate assay(s). Best lipolytic isolates were further quantitatively analyzed for lipase production, using substrate p-nitrophenyl palmitate (p-NPP). Cultures were characterized by morphological and molecular studies. The potent lipase producing strain of actinomycete was optimized for pH, temperature, inoculum size, carbon and nitrogen sources. Further, the lipolytic strain of actinomycete was grown on synthetic media and growth factors were optimized by RSM (Response Surface Methodology) for maximum production of lipase. Total 49 cultures were obtained from enriched soap-stock samples; among them 7 isolates were strains of actinomycete. Potent actinomycete strains were identified as Nocardiopsis alba, Streptomyces leeuwenhoekii, Streptomyces caelestis, Streptomyces werraensis and Streptomyces sclerotialus. Based on quantitative lipase production study, Nocardiopsis alba was selected as the best lipase producer. Optimized results of process parameter studies for lipase production by Nocardiopsis alba were: 5mL inoculum size, temperature 40 ∘ C, shaking at 130 rpm, pH 8.0 and cottonseed oil as the best carbon source. Cottonseed oil, K2HPO4 and cellulose were noted as main factors as optimized by Central Composite Design (CCD), where the culture showed highest (65.78 U/mL/min) lipase production. Findings of the research would offer potential environmental benefits along with socio-economic benefits if implemented suitably.

31 citations


Journal ArticleDOI
20 Nov 2021-Fuel
TL;DR: In this paper, a review paper aims at the health and environmental impacts of waste which rises the need for converting the waste into different types of renewable energy sources, including bio-based fuel from waste with simultaneous management of waste in a sustainable manner.

29 citations


Journal ArticleDOI
01 Dec 2021
TL;DR: In this article, the authors evaluate the repurposing of an anti-HIV drug Darunavir Ethanolate in COVID-19 treatment with in-silico study and discuss the therapeutic progress of DARUNAVIR Etanolate, to prevent SARS-CoV-2 replication.
Abstract: Antivirals already on the market and expertise gained from the SARS and MERS outbreaks are gaining momentum as the most effective way to combat the coronavirus outbreak. SARS-CoV-2 has caused considerable mortality due to respiratory failure, highlighting the immediate need for successful therapies as well as the long-term need for antivirals to combat potential emergent mutants of coronaviruses. There are constant viral mutations are being observed due to which world is experiencing different waves of SARS-CoV-2. If our understanding of the virology and clinical presentation of COVID-19 grows, so does the pool of possible pharmacological targets. In COVID-19, the difficulties of proper analysis of current pre-clinical/clinical data as well as the creation of new evidence concerning drug repurposing will be crucial. The current manuscript aims to evaluate the repurposing of an anti-HIV drug Darunavir Ethanolate in COVID-19 treatment with in silico study and we discuss the therapeutic progress of Darunavir Etanolate, to prevent SARS-CoV-2 replication, which supports its clinical assessment for COVID-19 therapy.

19 citations


Journal ArticleDOI
TL;DR: It can be derived that clove oil loaded microemulsion based gel can be a promising alternative to current antifungal regimens.
Abstract: A widespread of superficial fungal infections deals with concerns related to current therapeutic regimen such as drug resistance and adverse events associated with the same which leads exploration of natural oils as an antifungal agent. The aim of present work is to the development of clove oil loaded microemulsion based gel for treatment of superficial fungal infections. The microemulsion based gel was prepared by phase titration method and optimized using D-optimal design considering globule size, drug permeation and drug retention on skin as critical quality attributes. The MIC and zone of inhibition of clove oil was found to be 2.2 mg/ml and 38 mm respectively. A pale to yellowish transparent microemulsion had a globule size, zeta-potential and PDI of 14.41 nm, 0.73 and 0.0113 respectively indicating a stable microemulsion. A clove oil loaded microemulsion based gel (CLMBG) with a pH of 6.27 and viscosity of 12.87 m.pas/sec exhibited a comparable texture profile to marketed preparation. The drug release of the CLMBG with a drug content of 102.6 ± 4% in acetate buffer pH 5.5 was 98.5 ± 0.35% ensuring complete drug release from the formulation. Ex-vivo drug permeation study and skin irritation study dictated the retention of drug at site of action and the formulation to be non-irritant. The antifungal study proved the formulation to have similar efficacy as the marketed product (clobet gel). The stability study indicated the product to be safe, efficacious and stable formulation. From the above results, it can be derived that clove oil loaded microemulsion based gel can be a promising alternative to current antifungal regimens.

Journal ArticleDOI
TL;DR: In this article, Nocardiopsis alba was isolated from the soap-stock of an oil refinery located in North Gujarat, India and the 3D model was predicted by SWISS Modeling.

Journal ArticleDOI
TL;DR: In this paper, a remedial pathway for the process of dye degradation is proposed where the catalytic activity of Pd is faciled by the transfer of electrons from MCPTH to the metal centre.
Abstract: One-pot synthesis of palladium nanoparticles (PdNPs) has been achieved using calix[4]pyrrole hydrazide (MCPTH) as both reducing as well as capping agent. The synthetic procedure involves the use of environmentally benign water as solvent media. MCPTH-PdNPs have been characterized by using various analytical techniques. Transmission electron microscope analysis visualized the presence of well-dispersed and spherical Pd nanoparticles with an average dimension of 3–4 nm. Powder X-ray diffraction pattern portrayed the presence of face-centered cubic crystal structured PdNPs. A zeta potential value of − 26.2 mV suggests better stability of the nanoparticles. The heterogeneous catalytic activity of MCPTH-PdNPs was studied by probing the reduction of two carcinogenic azo dyes, namely, methylene blue and methyl orange in the presence of sodium borohydride. A remedial pathway for the process of dye degradation is proposed where the catalytic activity of Pd is faciled by the transfer of electrons from MCPTH to the metal centre. The mechanism for dye degradation is further substantiated by Density Functional Theory (DFT) calculations. The results of this work provide not only insight into fabrication of nanoparticles using calixarene platforms but also open new vistas to environmental remediation.

Journal ArticleDOI
12 Jan 2021
TL;DR: In this paper, metal-organic ionic frameworks (MOIFs) were used for the adsorption of toxic organic pollutants and as a self-rota for self-assembly.
Abstract: Herein, we report metal–organic ionic frameworks (MOIFs; an ionic product of an anionic complex and an organic cationic head group) for the adsorption of toxic organic pollutants and as a self-rota...

Journal ArticleDOI
TL;DR: In this article, the structural, adsorption, and electronic properties of one-dimensional (1D) metallic (Pd and Pt) nanowires using density functional theory (DFT) were analyzed.
Abstract: In this work, we report that palladium (Pd) and platinum (Pt) nanowires (NWs) are excellent materials for hydrogen storage by comparing the USDOE (United states department of energy) criteria. Here, we have focused on the structural, adsorption, and electronic properties of one-dimensional (1D) metallic (Pd and Pt) NWs using density functional theory (DFT). The band structure of all the systems shows the metallic nature. The maximum adsorption energies of hydrogen (H2) molecules are −5.06 eV and −4.25 eV for Pd and Pt NWs, respectively. The chemisorbed absorption occurs and therefore, the surface ionic bonding of NWs plays a significant role in the facilitation of H2 adsorption. The hydrogen adsorption based on Pd NW depends on reaction and recovering rates, which is directly related to their surface/volume ratio and brings to hydrogen adsorption. The hydrogen gravimetric storage capacities are found at 9.01 wt. % for Pd MNWs and 5.04 wt. % for Pt NWs, respectively.

Book ChapterDOI
01 Jan 2021
TL;DR: This research aims to study various consensus mechanisms in blockchain technology with their strengths and challenges, and discusses factors affecting the consensus mechanism and provides suggestions for drafting an effective consensus mechanism.
Abstract: Blockchain technology is a cryptographic technique that enables users to maintain their data in a decentral way with a non-editable form without an arbitrator. Originally motivated from the underlying platform of bitcoin cryptocurrency, researchers found blockchain to be very useful in many application domains, including smart contracts, insurance, banking, finance, and many other sectors. As multiple stakeholders try to add a block (containing the data or transactions) into the chain, there is a need for a mechanism to come to an agreement on which stakeholder’s block should be added. Such a mechanism is known as consensus mechanism which is a primary factor of significance because it decides the correctness of data to be added as well as trustworthiness of the node which is attempting to add the block. An efficient consensus mechanism achieves security, higher precision, and better performance. In this research, we aim to study various consensus mechanisms in blockchain technology with their strengths and challenges. We discuss factors affecting the consensus mechanism and provide our suggestions for drafting an effective consensus mechanism.

Journal ArticleDOI
TL;DR: Two new homologous series of Schiff base derivatives with lateral methyl substitution having central cinnamates VIn and benzoates VIIn moiety were prepared in this paper.
Abstract: Two new homologous series of Schiff’s base derivatives with lateral methyl substitution having central cinnamates VIn and benzoates VIIn moiety were prepared. All the compounds were characterised w...

Journal ArticleDOI
TL;DR: Alteration in the pattern of epigenetic marking leads to cancer, neurological disorders, inflammatory problems etc.
Abstract: Alteration in the pattern of epigenetic marking leads to cancer, neurological disorders, inflammatory problems etc. These changes are due to aberration in histone modification enzymes that function as readers, writers and erasers. Bromodomains (BDs) and BET proteins that recognize acetylation of chromatin regulate gene expression. To block the function of any of these BrDs and/or BET protein can be a controlling agent in disorders such as cancer. BrDs and BET proteins are now emerging as targets for new therapeutic development. Traditional drugs like enzyme inhibitors and protein–protein inhibitors have many limitations. Recently Proteolysis-Targeting Chimeras (PROTACs) have become an advanced tool in therapeutic intervention as they remove disease causing proteins. This review provides an overview of the development and mechanisms of PROTACs for BRD and BET protein regulation in cancer and advanced possibilities of genetic technologies in therapeutics.

Journal ArticleDOI
TL;DR: In this article, the authors have introduced pressure acoustic transient model of vibro cleaning application by means of COMSOL multiphysics software, which is of the multi physics coupling simulation software.

Journal ArticleDOI
TL;DR: In this article, the recovery of metals from electronic waste was investigated by using fungal strain Aspergillus fumigatus A2DS, isolated from the mining industry wastewater.

Journal ArticleDOI
TL;DR: In this article, the synthesis of Zinc Oxide nanoparticles (ZnO NPs) using the sol-gel method at discrete calcination temperatures (500 °C, 700‌C, 900‌°C).

Journal ArticleDOI
TL;DR: In this paper, the authors used density functional theory (DFT) for the dissociation of noxious gas molecules such as carbon and nitrogen-based molecules (CO, CO2, N2, NH3, NO, and NO2) on a pentagonal two-dimensional beryllium diphosphide (BeP2).

Journal ArticleDOI
TL;DR: The HPLC method showed a successful application for determination of Formoterol Fumarate and Budesonide in Inhalation suspension pharmaceutical formulation.
Abstract: Formoterol Fumarate and Budesonide inhalation suspension is prescribed for treatment of Asthmatic patient. Formoterol Fumarate is anti-asthmatic drug (Bronchodilator) and Budesonide is Anti Inflammatory Drug (Glucocortico steroid) drug. A bronchodilator is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lungs while Anti Inflammatory drug is used for the treatment of inflammation occurred on respiratory tract. The present study aimed to Validate HPLC method for combined determination of Assay of Formoterol Fumarate and Budesonide Analytes. This study covers Precision, Limit of Detection, Limit of Quantification, Linearity, Accuracy, Robustness, Ruggedness, Solution stability and Specificity. The chromatographic method uses a reversed phase column Hypersil ODS 125mm ×4.0mm x 5μm). The mobile phase was prepared by mixing Acetonitrile: Phosphate buffer (35:65, %v/v) at flow rate 1.0ml/min with Ultraviolet and Diode array detector at wavelength 215nm, column oven adjusted to 40°C and with injection volume 50μL. The method Found Precise, Accurate, Linear, Rugged, Robust and Sensitive. The method showed a successful application for determination of Formoterol Fumarate and Budesonide in Inhalation suspension pharmaceutical formulation.

Book ChapterDOI
01 Jan 2021
TL;DR: This chapter focuses on the distinctiveStructural similarity with metal coordination complexes alongside modifiable pore sizes and splendid functionalization extents are the major distinctions propelling MOFs’ utility-based advancement in drug delivery.
Abstract: Never-ending desire to have better health care has enabled several ways out for improving the biodistribution and aqueous solubility of conventional drugs Consequently, rigorous investigations have been and are being conducted to ensure site-specific drug delivery with minimal structural degradation till a drug reaches its targeted location Designing self-adjusting and response tunable drug delivery systems capable of tolerating physiological fluctuations has been the prime focus of present-day health-care research In this context, metal-organic frameworks (MOFs) have emerged as significant advancements, characterized by their high pore volumes, large surface areas, multiple topologies, and dynamic surface chemistry The chief attributes of MOFs making them astute drug carriers include their exceptionally high porosity extents (up to 90% of free volume) and functionalization abilities Apart from this, inherent structural stability through self-assembly enabled linkage of connector and an organic linker, through a strong covalent bond, imparts them porous crystalline morphology for transporting significant drug payloads Structural similarity with metal coordination complexes alongside modifiable pore sizes and splendid functionalization extents are the major distinctions propelling MOFs’ utility-based advancement in drug delivery Nevertheless, optimizations ensuring safe drug delivery, along with lowest side effects and sustained release profile, have moderate the commercial acceptance of MOFs With such insights, this chapter focuses on the distinctive structural aspects of MOFs pertaining to their drug delivery advances

Journal ArticleDOI
TL;DR: In this paper, two homologous series of λ-shape to T-shape mesogenic azo diesters were synthesized, and their thermotropic properties were studied by differential scanning calorimetry and a hot-stage polarizing optical microscope.

Journal ArticleDOI
TL;DR: In this paper, bovine serum albumin nanoparticles (BSA-NPs) were found within 50 to 75nm range confirmed by dynamic light scattering and scanning electron microscope.


Journal ArticleDOI
TL;DR: In this paper, the effect of position isomer in newly synthesized two liquid crystalline series having nitro and chloro groups at terminal and lateral position, with imine and cinnamoyloxy linkages was studied.

Journal ArticleDOI
TL;DR: In this article, the Finite Volume numerical scheme has been used to solve one-dimensional unsteady state and two-dimensional steady-state heat flow problems with the initial condition and Dirichlet boundary condition.

Journal ArticleDOI
TL;DR: Graphene dependent attenuators and single and multi-frequency constructible antennas are designed employing the tunability of graphene in this article, where the authors claim that printed graphene has the potential to be a competent alternative for RFID applications.
Abstract: Many researchers claim that graphene, a specially studied carbon allotrope, has a single layer of atoms organized in a two-dimensional honeycomb lattice. Because of its exceptional electronic and mechanical properties, it has a significant job to perform in redefining future technologies. Although graphene has made a major breakthrough to be considered for a wide area of applications, most of the interesting properties of graphene are still at the early stage of research. Graphene dependent attenuators and single and multi-frequency constructible antennas are designed employing the tunability of graphene. As the name indicates, the form of RF technology that uses electromagnetic fields for automatic identification purposes of tags attached to objects is termed as radio frequency identification (RFID). For years, the use of pricy raw materials and intricate fabrication processes in metal coating and metal based conductive inks in printed electronics kept the involved cost very high. So, it is inevitable to replace the existing fabrication process with cheaper materials and simpler techniques. Researchers assert that printed graphene has the potential to be a competent alternative for RFID applications.