Institution
Karolinska Institutet
Education•Stockholm, Sweden•
About: Karolinska Institutet is a education organization based out in Stockholm, Sweden. It is known for research contribution in the topics: Population & Cancer. The organization has 46212 authors who have published 121142 publications receiving 6008130 citations.
Topics: Population, Cancer, Poison control, Cohort study, Health care
Papers published on a yearly basis
Papers
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TL;DR: It is demonstrated that HIF-1α showed hypoxia-dependent translocation from the cytoplasm to the nucleus and that this regulatory mechanism was severely impaired in the presence of proteasome inhibitors, demonstrating that the mechanism of hypoxIA-dependent activation of Hif-1 α is a complex multistep process and that stabilization of HIF -1α protein levels is not sufficient to generate a functional form.
780 citations
779 citations
Karolinska Institutet1, University of Oxford2, University of Toronto3, Centre national de la recherche scientifique4, University of California, Berkeley5, Los Alamos National Laboratory6, Tsinghua University7, University of Science and Technology of China8, Weizmann Institute of Science9, Scripps Research Institute10, Novartis11, Argonne National Laboratory12, Yeshiva University13, Brookhaven National Laboratory14, Rutgers University15, Case Western Reserve University16, University of California, San Francisco17, Columbia University18, Max Delbrück Center for Molecular Medicine19, New York University20
TL;DR: This review presents methods that could be applied at the outset of any project, a prioritized list of alternate strategies and a list of pitfalls that trip many new investigators.
Abstract: In selecting a method to produce a recombinant protein, a researcher is faced with a bewildering array of choices as to where to start. To facilitate decision-making, we describe a consensus 'what to try first' strategy based on our collective analysis of the expression and purification of over 10,000 different proteins. This review presents methods that could be applied at the outset of any project, a prioritized list of alternate strategies and a list of pitfalls that trip many new investigators.
778 citations
Harvard University1, Medical University of Vienna2, Institut Jules Bordet3, University of St. Gallen4, Kantonsspital St. Gallen5, Institut Gustave Roussy6, Memorial Sloan Kettering Cancer Center7, Karolinska Institutet8, University of Bordeaux9, University of North Carolina at Chapel Hill10, Queen Mary University of London11, Charité12, Marmara University13, Mount Sinai Hospital, Toronto14, Ludwig Maximilian University of Munich15, University of Michigan16, National Taiwan University17, University of Ulm18, National Institutes of Health19, Gdańsk Medical University20, Sahlgrenska University Hospital21, Baylor College of Medicine22, University of Toronto23, Netherlands Cancer Institute24, Paracelsus Private Medical University of Salzburg25, Fudan University26, The Royal Marsden NHS Foundation Trust27, Kyoto University28, Institute of Cancer Research29, University of Milan30, McMaster University31
TL;DR: The 15th St. Gallen International Breast Cancer Conference 2017 in Vienna, Austria reviewed substantial new evidence on loco-regional and systemic therapies for early breast cancer, and recommended bisphosphonate use in postmenopausal women to prevent breast cancer recurrence.
777 citations
TL;DR: Overall results indicate equivalence, but there have been few studies of the individual psychiatric and somatic conditions so far, and for the majority, guided ICBT has not been compared against face-to-face treatment.
Abstract: During the last two decades, Internet-delivered cognitive behavior therapy (ICBT) has been tested in hundreds of randomized controlled trials, often with promising results. However, the control gro...
775 citations
Authors
Showing all 46522 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Meir J. Stampfer | 277 | 1414 | 283776 |
| Albert Hofman | 267 | 2530 | 321405 |
| Guido Kroemer | 236 | 1404 | 246571 |
| Eric B. Rimm | 196 | 988 | 147119 |
| Scott M. Grundy | 187 | 841 | 231821 |
| Jing Wang | 184 | 4046 | 202769 |
| Tadamitsu Kishimoto | 181 | 1067 | 130860 |
| John Hardy | 177 | 1178 | 171694 |
| Marc G. Caron | 173 | 674 | 99802 |
| Ramachandran S. Vasan | 172 | 1100 | 138108 |
| Adrian L. Harris | 170 | 1084 | 120365 |
| Douglas F. Easton | 165 | 844 | 113809 |
| Zulfiqar A Bhutta | 165 | 1231 | 169329 |
| Judah Folkman | 165 | 499 | 148611 |
| Ralph A. DeFronzo | 160 | 759 | 132993 |